‘Light treatment’? The burden of treatment in ultraviolet B phototherapy
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Ultraviolet b
Narrow-band ultraviolet B (NB-UVB) therapy has been used successfully for the treatment of inflammatory and pigmentary skin disorders including atopic dermatitis, psoriasis, mycosis fungoides, polymorphous light eruption, and vitiligo.This is a retrospective review of the treatment outcomes of 117 consecutive patients with vitiligo, pruritus, and other inflammatory dermatoses, excluding those with psoriasis and CTCL, who were treated with NB-UVB between 1998 and 2001 at our institution.Approximately 80% of all patients showed improvement in their condition. NB-UVB phototherapy was well tolerated, with no serious adverse effects. In patients with vitiligo, 6.4% had an abnormal thyroid-stimulating hormone level and 6.5% had anemia.NB-UVB may be considered as a viable therapeutic option in the treatment of vitiligo, pruritus, and other inflammatory dermatoses. Long-term adverse effects and cost-benefit analysis of NB-UVB therapy compared to other treatment modalities remain to be determined.
Vitiligo
Ultraviolet therapy
Ultraviolet b
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The sudden eruption of bullae within psoriatic plaques is an uncommon adverse effect of narrow-band UVB phototherapy (TL-01 radiation). We report the case of a 49-year-old man who developed a bullous eruption after several NB-UVB treatments and will review important aspects of this unusual phototherapy complication.
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Background: Psorasis is a complex, chronic multifactorial inflammatory skin disease characterised by well demarcated, erythematous, scaly plaques on the extensor surface's of the body and scalp. The purpose of the study to compare the efficacy and safety of systemic PUVA and UVB phototherapy in the management of chronic plaque psoriasis.
Materials and methods: This comparative study was conducted at the Department of Dermatology and Venereology, Bangabandhu Memorial Hospital, USTC, Chattogram during the period of February 2018 to January 2019. Total 50 patients were selected in two groups, systemic PUVA (Psoralen and Ultraviolet A) (n=25) and UVB (Ultraviolet B) (n=25). Involvement of body surface by plaque psoriasis, erythema, scaling and induration were recorded in a 3 point scale before treatment and 14 days interval after giving PUVA or UVB and finally at 8th week.
Results: Significant reduction of psoriasis at 1st follow up in systemic PUVA and UVB were 29.85 ± 8.95 and 31.93 ± 11.55 respectively and at 2nd follow up were 85.86 ± 7.33 and 28.48 ± 39.32 respectively. Significantly higher improvements was observed in systemic PUVA group than UVB group both at 1st and 2nd follow up.
Conclusion: Therapeutic values of systemic PUVA is better than UVB phototherapy in the management of Chronic plaque psoriasis.
IAHS Medical Journal Vol 4(2), June 2021; 47-50
Venereology
Erythema
PUVA therapy
Ultraviolet b
Body surface area
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摘要： 【摘要】 我国窄谱中波紫外线应用于白癜风治疗已有十余年，目前，其临床治疗参数尚缺乏统一标准，不规范的治疗不仅不能使患者从中获益，还易引起红斑、水疱、光老化等不良反应。基于世界白癜风工作组光疗委员会制定的窄谱中波紫外线治疗白癜风的专家共识，结合相关文献及临床治疗经验，本文从治疗频率、初始治疗剂量、连续治疗或中断治疗后剂量调整、平台期及疗程选择、可接受的最大光疗总次数等方面讨论窄谱中波紫外线治疗参数的选择，提高窄谱中波紫外线治疗白癜风的疗效。
Vitiligo
Ultraviolet b
Narrowband
Ultraviolet B radiation
Ultraviolet
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PUVA therapy
Granuloma Annulare
Ultraviolet b
Vitiligo
Ultraviolet therapy
Phototype
Phototoxicity
Methoxsalen
Ultraviolet a
Erythema
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Vitiligo
Ultraviolet b
Dermatopathology
Ultraviolet a
PUVA therapy
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Phototherapy methods commonly used in the treatment of vitiligo include narrow-band ultraviolet B (NB-UVB). A 23-years old male was diagnosed with vitiligo in the dermatology polyclinic and was followed up in the phototherapy unit with NB-UVB treatment of 3 sessions per week; in the 42nd session psoriasis plaques were seen to have developed. We suggest that this rare but important association should be considered as a side effect of narrow-band phototherapy.
Vitiligo
Ultraviolet b
Ultraviolet therapy
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Depigmentation
Vitiligo
Hypopigmentation
Ultraviolet b
Erythema
PUVA therapy
Methoxsalen
Calcipotriol
Ultraviolet therapy
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Ultraviolet (UV) radiation has been applied to treat many chronic skin diseases. Based on the wavelength, UV radiation consists of three types, namely ultraviolet C (UVC), ultraviolet B (UVB), and ultraviolet A (UVA). The types of UV that are widely used in dermatology are narrowband ultraviolet B (NB-UVB), broadband ultraviolet B (BB-UVB), UVA1, and psoralen combined with UVA (PUVA). The interaction between UV and the skin determines the effectiveness of phototherapy. The biological effects of UV are used in the management of inflammatory skin diseases, malignancies, and various rare dermatoses. Apart from these benefits, UV increases the risk of photoaging and skin cancer. Therefore, further researches are necessary to enhance the effectiveness and safety of phototherapy. This literature review discusses the role of phototherapy in various dermatoses other than psoriasis and vitiligo.
Vitiligo
Photoaging
Ultraviolet b
Ultraviolet B radiation
Ultraviolet a
Ultraviolet
Ultraviolet light
Ultraviolet therapy
PUVA therapy
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