Effectiveness and safety of acupuncture for postoperative ileus following gastrointestinal surgery: A systematic review and meta-analysis
13
Citation
56
Reference
10
Related Paper
Citation Trend
Abstract:
Background Postoperative ileus (POI) is an important complication of gastrointestinal (GI) surgery. Acupuncture has been increasingly used in treating POI. This study aimed to assess the effectiveness and safety of acupuncture for POI following GI surgery. Methods Seven databases (PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure, Wan fang Data, VIP Database for Chinese Technical Periodicals, and Chinese Biomedical Literature Database) and related resources were searched from inception to May 30, 2021. Randomized controlled trials (RCTs) reporting the acupuncture for POI in GI were included. The quality of RCTs was assessed by the Cochrane Collaboration Risk of Bias tool, and the certainty of the evidence was evaluated by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. A meta-analysis was performed by using RevMan 5.4 software. Results Eighteen RCTs involving 1413 participants were included. The meta-analysis showed that acupuncture could reduce the time to first flatus (TFF) (standardized mean difference [SMD] = −1.14, 95% confidence interval [CI]: −1.54 to −0.73, P < 0.00001), time to first defecation (TFD) (SMD = −1.31, 95% CI: −1.88 to −0.74, P < 0.00001), time to bowel sounds recovery (TBSR) (SMD = −1.57, 95% CI: −2.14 to −1.01, P < 0.00001), and length of hospital stay (LOS) (mean difference [MD] = −1.68, 95% CI: −2.55 to −0.80, P = 0.0002) compared with usual care. A subgroup analysis found that acupuncture at distal acupoints once daily after surgery had superior effects on reducing TFF and TFD. A sensitivity analysis supported the validity of the finding. Acupuncture also manifested an effect of reducing TFF, TFD and TBSR compared with sham acupuncture but the result was not stable. Relatively few trials have reported whether adverse events have occurred. Conclusions Acupuncture showed a certain effect in reducing POI following GI surgery with very low-to-moderate quality of evidence. The overall safety of acupuncture should be further validated. More high-quality, large-scale, and multicenter original trials are needed in the future.Keywords:
Subgroup analysis
Ileus
Subgroup analysis
Cite
Citations (73)
[목적] 이 메타분석 연구의 목적은 웨이트트레이닝이 골퍼의 골프 수행능력과 주요 체력요인에 대한 효과를 평가 하는 것이었다. [방법] 결과 도출을 위해 Pubmed, Cochrane Library, RISS를 이용하여 검색을 진행하였다. 연구의 질 평가를 위해 Cochrane ROB (risk of bia)을 사용하였다. 효과크기는 표준화된 평균차(standardized mean difference; SMD) 및 95% CI를 선택하고, 랜덤효과모형(random-effect model)을 이용하였다, 선정된 연구의 통계적 이질성은 Cochrane의 Q 테스트와 I2 통계량을 통하여 평가 되었다. [결과] 연구 결과 웨이트트레이닝은 클럽헤드스피드(ES=0.53, 95%CI 0.14-0.92, p=0.008), 비거리(ES=0.62, 95%CI 0.25-0.99, p=0.001), 볼 스피드(ES=0.62, 95% CI 0.21-1.03, p=0.003) 와 근파워(ES=2.55, 95% CI 1.19-3.91, p=0.0002), 근력(ES=0.60, 95% CI 0.24-0.96, p=0.0009)을 향상시키는 것으로 나 타났다. [결론] 결론적으로 웨이트트레이닝은 골프 선수 및 아마추어 골퍼의 골프 수행력과 체력요인을 향상 시키 는데 효과적인 중재방법임을 확인할 수 있었다. 이러한 결과는 골퍼의 골프 수행 능력 향상을 위한 훈련프로그램 에 웨이트트레이닝이 포함되어야 할 것을 시사한다.
Mean difference
Cite
Citations (0)
Ear acupuncture might be the form of acupuncture best suited to improving acute pain management in the emergency department (ED). The primary aim of this review was to assess the analgesic efficacy of ear acupuncture in the ED. Secondary outcomes included measures of patient satisfaction, adverse effects, cost, administration techniques, and reduction of medication usage.
Cite
Citations (116)
Objective: The primary purpose of our study is to systemically evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) on recovery of dysphagia after stroke. Search Methods: We searched randomized controlled trials (RCTs) and non-RCTs published by PubMed, the Cochrane Library, ScienceDirect, MEDLINE, and Web of Science from inception until April 24, 2021. Language is limited to English. After screening and extracting the data, and evaluating the quality of the selected literature, we carried out the meta-analysis with software RevMan 5.3 and summarized available evidence from non-RCTs. Results: Among 205 potentially relevant articles, 189 participants (from 10 RCTs) were recruited in the meta-analysis, and six non-RCTs were qualitatively described. The random-effects model analysis revealed a pooled effect size of SMD = 0.65 (95% CI = 0.04-1.26, p = 0.04), which indicated that rTMS therapy has a better effect than conventional therapy. However, the subgroup analysis showed that there was no significant difference between low-frequency and high-frequency groups. Even more surprisingly, there were no statistically significant differences between the two groups and the conventional training group in the subgroup analysis, but the combined effect was positive. Conclusion: Our study suggests that rTMS might be effective in treating patients with dysphagia after stroke.
Subgroup analysis
Stroke
Web of science
Cite
Citations (14)
Copper dyshomeostasis can lead to many diseases, including cardiovascular disease. However, there are conflicting reports on the relationship between serum copper and heart failure (HF). To explore the relationship between serum copper levels and HF by performing a meta-analysis.The PubMed and ScienceDirect databases until June 2019 were searched for reports on the association between serum copper levels and HF.A total of thirteen studies including 1504 subjects were chosen for the meta-analysis. The pooled analysis indicated that patients with HF had higher serum copper than the control subjects [standardized mean difference (SMD), 0.982; 95% confidence interval (CI), (0.679, 1.285)]. Subgroup analysis stratified by different geographic locations found that HF patients had higher copper than the control subjects in Asia and Europe [Asia: SMD, 0.948 and 95% CI, (0.569, 1.327); Europe: SMD, 1.275 and 95% CI, (0.633, 1.917)], but not in America [America: SMD, 0.637 and 95% CI, (-0.109, 1.383)]. Additionally, subgroup analysis revealed that patients with ischemic cardiomyopathy (ICM) [SMD, 1.171; 95% CI, (0.717, 1.624)], idiopathic dilated cardiomyopathy (IDCM) [SMD, 0.569; 95% CI, (0.097, 1.042)] and other types of HF [SMD, 1.152; 95% CI, (0.594, 1.710)] all had higher copper levels than controls. Further subgroup analysis stratified by Newcastle-Ottawa Scale (NOS) scores also found higher serum copper in patients with HF than controls within each subgroup.Our meta-analysis identified a significant association between high serum copper and HF.
Subgroup analysis
Dilated Cardiomyopathy
Cite
Citations (43)
Background and Objectives: Copper dyshomeostasis can lead to many diseases, including cardiovascular disease. However, there are conflicting reports on the relationship between serum copper levels and heart failure (HF). To explore the relationship between serum copper levels and HF by performing a meta-analysis. Methods and Study Design: The PubMed and ScienceDirect databases until June 2019 were searched for reports on the association between serum copper levels and HF. Results: A total of thirteen studies including 1504 subjects were chosen for the meta-analysis. The pooled analysis indicated that patients with HF had higher copper levels than the control subjects [standardized mean difference (SMD), 0.982; 95% confidence interval (CI), (0.679, 1.285)]. Subgroup analysis stratified by different geographic locations found that HF patients had higher copper levels than the control subjects in Asia and Europe [Asia: SMD, 0.948 and 95% CI, (0.569, 1.327); Europe: SMD, 1.275 and 95% CI, (0.633, 1.917)], but not in America [America: SMD, 0.637 and 95% CI, (-0.109, 1.383)]. Additionally, subgroup analysis revealed that patients with ischemic cardiomyopathy (ICM) [SMD, 1.171; 95% CI, (0.717, 1.624)], idiopathic dilated cardiomyopathy (IDCM) [SMD, 0.569; 95% CI, (0.097, 1.042)] and other types of HF [SMD, 1.152; 95% CI, (0.594, 1.710)] all had higher copper levels than controls. Further subgroup analysis stratified by Newcastle-Ottawa Scale (NOS) scores also found higher serum copper levels in patients with HF than controls within each subgroup. Conclusions: Our meta-analysis identified a significant association between high copper levels and HF.
Subgroup analysis
Dilated Cardiomyopathy
Pooled analysis
Cite
Citations (0)
본 메타분석 연구의 목적은 고지훈련이 지구력 스포츠 선수의 유산소성 능력에 미치는 효과를 평가하는 것이었다. 본 연구의 결과 도출을 위해 Pubmed, Cochrane Library, Web of Science의 Data Base를 활용하여 문헌검색을 수행하 였다. Cochrane ROB (risk of bia)을 사용하여 연구의 질을 평가하였다. 또한, 표준화된 평균차 standardized mean difference; SMD) 및 95% CI, 랜덤효과모형(random-effect model)을 이용하여 효과크기를 계산하였다, Cochrane 의 Q 테스트와 I2 통계량을 통하여 연구의 이질성을 평가하였다. 연구 결과 고지훈련은 지구력 스포츠 종목 선수의 최대산 소섭취량에 중간정도의 효과크기를 보이는 것으로 나타났다(SMD -.35, 95% CI –.61~-.08, p=0.01). 또한, 고지훈련 은 지구력 스포츠 종목 선수의 헤모글로빈 함량에 중간정도의 효과크기를 보이는 것으로 나타났다(SMD -.39, 95% CI –.73~-.05, p=0.02). 결론적으로 고지훈련이 지구력 스포츠 종목 선수들의 최대산소섭취량과 헤모글로빈 함량에 유의한 개선이 나타났다. 이러한 결과는 지구력 스포츠 선수의 유산소성 능력 향상을 위한 훈련프로그램에 고지훈련이 효과가 있음을 시사한다.
Mean difference
Aerobic capacity
Aerobic Exercise
Web of science
Cite
Citations (0)
Objective
To systematically assess the efficacy and safety of Kanglaite combined with chemotherapy on advanced non-small cell lung cancer compared with chemotherapy alone.
Methods
We searched systematically literatures from Medline, Embase, Cochrane Library, Web of Science, CBM, CNKI, VIP, and WanFang.Papers were screened according to the inclusion and exclusion criteria, and then the data were extracted.Meta analysis was conducted using Stata 12.0 software.
Results
A total of 17 randomized controlled trials and a total of 1 151 patients were included in this study.Meta analysis showed that the short-term effect of experimental group was generally higher than that of control group (RR=1.51, 95%CI: 1.30-1.76, P<0.001). Subgroup analysis showed that Kanglaite combined with GP or PVM could significantly improve the short-time effect (P=0.026, 0.027 respectively). The improvement of KPS grade of experimental group was generally higher than that of control group (RR=1.51, 95%CI: 1.37-1.66, P<0.001). Subgroup analysis showed that Kanglaite combined with NP or CAP could significantly improve KPS grade (all P=0.000). The morbidity of nausea and vomiting of experimental group was generally lower than that of control group (RR=0.53, 95%CI: 0.44-0.64, P<0.001). Subgroup analysis showed that Kanglaite combined with GP or NP could significantly decrease the morbidity of nausea and vomiting (P=0.010, 0.004 respectively).
Conclusions
For patients with advanced non-small cell lung cancer, Kanglaite combined with chemotherapy can improve the short-time effect, the quality of life, and decrease the occurrence of adverse reaction.
Key words:
Non-small cell lung cancer; Kanglaite combined with chemotherapy; Chemotherapy; Meta analysis
Subgroup analysis
Cite
Citations (1)
Stroke
Subgroup analysis
Cite
Citations (8)
To compare the incidence of postoperative ileus following laparoscopic and open radical resection for colorectal cancer using meta-analysis.The Cochrane library, Pubmed, Ovid databases were searched as of October 2011. Two reviewers extracted the data and assessed the methodological quality independently. The homogeneity of studies was evaluated and the meta-analysis was conducted by the Cochrane Collaboration RevMan 5.0 software.Seven studies including 3630 cases were analyzed. A total of 1814 patients received laparoscopic surgery, of whom 58 developed postoperative ileus. There were 1816 cases undergoing open surgery, of whom 105 developed early postoperative ileus. The pooled relative risk was 0.55 with a 95% confidence interval of 0.41-0.76. The difference was statistically significant(P<0.01).Compared with open surgery, laparoscopic colorectal resection can reduce the incidence of postoperative ileus.
Ileus
Colorectal Surgery
Open surgery
Cite
Citations (2)