Infantile hydrocephalus: A retrospective cohort of 467 patients from a single center
Yohan CaudronKévin BeccariaMarie BourgeoisSandro BenichiLelio GuidaSyril JamesGiovanna PaternosterThomas Blauwblomme
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Our purpose is to study the aetiologies of congenital cataracts, and to establish an approach to decision making of etiological diagnosis.We included 85 children in a cross sectional study. The mean age was 4.5 years. These patients underwent a complete ophthalmologic and paediatric examination, and etiological investigation.An aetiology of congenital cataracts was found in 62.5% of cases. Hereditary was the most common cause, it constituted 42.3% of etiologies. Among these cases 77.7% were autosomal recessive. 16.4% of congenital cataracts were associated with general diseases or dysmorphology syndromes. Metabolic diseases and intrauterine infections were found in 7 % and 4.7% of cases respectively.Heredity remains the most common etiology of congenital cataracts.
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102 children with uveitis were followed up in both an ophthalmological clinic and in private practice. These cases were studied, using the same criteria for the anatomical and etiological classification. For each etiology arguments for certitude and probability were cautiously defined. The etiology could be ascertained in about 36.5% of the cases. Arguments for a presumptive etiology were found in about 23.1% more cases. The first cause was toxoplasmosis; the second cause was streptococcic hypersensitivity. An etiology was rarely found for intermediate uveitis.
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Aim: To investigate whether severe acute respiratory syndrome coronavirus is involved in the etiology of acute pancreatitis.
Material and Methods: This study was conducted in Çiğli Educational Hospital, Bakırçay Univesity. The study included 2060 patients with AP admitted to hospital between March, 2020 and August, 2023. The patients were assigned into 2 groups based on presence of COVID-19 infection. Ethiological factors for AP were determined in all patients.
Results: Gallstone was the etiological factor in 614 patients (32.9%) who were COVID (-) but it was the etiological reason in only 19 patients (19%) in COVID (+) group. No etiology was identified in 217 (11.6%) of COVID (-) patients who were diagnosed as idiopathic pancreatitis. Idiopathic pancreatitis was diagnosed in 107 cases (54%) in COVID (+) group. There was significant difference presence of the diagnosis, which was made according to etiological factor, between groups.
Conclusion: There was no definitive etiological link between COVID-19 and AP; however, the fact that same team diagnosed such a different idiopathic AP in the same hospital with same diagnostic facilities implies an etiological role for SARS-CoV-2 virus in AP.
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To evaluate whether radiological findings and healing time in children with pneumonia are correlated to etiologic agent.A total of 346 children with radiologically verified acute pneumonia, and with accomplished serological tests for bacteria and viruses, were included in the study. Five etiological groups were analysed: children with bacterial etiology only, with viral etiology only, with mixed bacterial and viral etiology, with Mycoplasma only, and children with no etiology.The chest films of each etiological group were analysed and the findings were correlated to the children's age. The radiological findings did not differ between the etiological groups. Radiological findings correlated significantly with the patient's age. The radiological healing frequency at check-up X-ray was found to be significantly lower in children with mixed bacterial and viral etiology compared to children in each of the other groups and to the material as a whole.Conclusions about the etiology could not be drawn from the chest X-ray findings.
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Etiology and pathogenesis of MCA/MR in 1,023 patients (618 male; 405 female) with mental retardation were studied. Of 1,023 patients, there were 563 cases (317 male; 246 female) with MCA (55%). Among the MCA patients, there were 303 (156 male; 147 female) whose primary etiology was clarified (53.8%). Among the 260 patients with MCA/MR of unknown etiology, there were 23 with recognizable syndromes of unknown etiology and 7 previously reported by us as possibly having a new malformation syndrome. We had 569 patients with mental retardation of unknown etiology including 236 (41.5%) who were involved with MCA.
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The purpose of this study was to investigate the clinical characteristics of children with mental retardation (MR) of unknown etiology for early recognition and intervention. In this study, we defined children with MR of unknown etiology as those without clear etiologies for MR despite extensive evaluation and were not associated with pathological behavioral problems such as pervasive developmental disorders and attention-deficit/hyperactivity disorder. The clinical characteristics of children with MR of unknown etiology were as follows. 1) MR of unknown etiology was 48.8% of all MR. 2) MR of unknown etiology was more common in males. 3) Delayed language development was a leading factor that made the parents of children with MR of unknown etiology seek help from physicians. However, most of the children with MR of unknown etiology showed a relatively uniform delay in several areas of development. 4) Most children with MR of unknown etiology were delayed walkers. 5) Most children with MR of unknown etiology were mild cases.
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One hundred cases of urticaria were studied to find out the etiology and to detect any co-relation between etiology and clinical manifestation. In 59% cases an etiological factor could be detected and the diagnosis was more certain in acute cases. In more than two-third of cases of chronic utricaria, the etiology could not be detected. Type and distribution of the lesions did not suggest any particular etiology except in the cases of physical and cholinergic urticaria.
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