Subthreshold micropulse laser treating residual macular subretinal fluid after rhegmatogenous retinal detachment surgery: A case report
0
Citation
9
Reference
10
Related Paper
Abstract:
We report the effect of micropulse laser (MPL) treating a case of residual subretinal fluid (SRF) after rhegmatogenous retinal detachment (RRD) surgery. A 38-year-old male patient presenting with residual SRF 6 months following RRD surgery. Initial central macular thickness (CMT) was 243 μm. A 3 × 3 MPL macular grid was performed with moderate reduction of SRF (CMT = 191 μm). Five months following second MPL session, we noted a complete resolution of SRF (CMT = 98 μm) and fundus autofluorescence did not show any laser scare. Micropulse laser might represent a new non-invasive efficient treatment for residual SRF after RDD surgery. MPL effect seemed to be delayed and close follow-up was necessary.Keywords:
Subthreshold conduction
Genentech is partnering with the German cancer company Affimed to develop immunotherapies for multiple kinds of solid and blood cancers. Affimed is developing therapies that engage natural killer cells of the innate immune system to help direct them to attack cancer cells. Genentech will pay Affimed $96 million up front and up to $5 billion more in potential payments.
Cite
Citations (0)
Retinal Tear
Cite
Citations (1)
Cite
Citations (0)
Purpose: To determine the effects of performing pneumoretinopexy in patients without the conventional indication of pneumoretinopexy but with rhegmatogenous retinal detachment by multiple retinal tears separated over 1 hour in distance. Methods: Three patients with rhegmatogenous retinal detachment by multiple retinal tears separated over 1 hour in distance from November 2003 to December 2003 were the subject of this study. Treatment records of the patients were examined retrospectively. In one case, when performing pneumoretinopexy, 0.5 cc of vitreous was aspirated followed by an injection of 0.8 cc gas. In the other two cases, after injecting 0.5 cc of SF6 gas, one retinal tear was adhered in the proper position. Then, sequential retinal adhesion was attempted by changing the position. Results: In all three cases, anatomical retinal adhesion was maintained, and visual acuity functionality was improved. Conclusions: Both sequential retinal adhesion by changing the position and performing pneumoretinopexy after vitreous aspiration are successful method of retinal adhesion. Therefore, pneumoretinopexy can be used as an effective medical treatment in patients with rhegmatogenous retinal detachment by multiple retinal tears separated over 1 hour in distance.
Retinal Tear
Cite
Citations (3)
Objective: To investigate the change of intraocular pressure and axial length on choriodal detachment associated with retinal detachment by different operations before and after operation and analyses clinical significance. Methods: 30 patients (30 eyes) with choriodal detachment associated with retinal detachment and whose retina were successful replaced in the first operation were col-lected from January, 2006 to December, 2006 in our hospital. IOP and axial length were measured with Goldmann tonometer and A scan at the moment of diagnosis,1 day preoperatively with the treatment of glucocorticoid and 1 week, 1,3,6 months postoperatively. To sum-marize the change rule of IOP and axial length on choriodal detachment associated with retinal detachment eyes whose retinas were suc-cessfully replaced, and to analyze the relation between the IOP, axial length and the course of disease. Results: 1. At the moment of diag-nosis, the mean IOP of all patient’s health eyes was 13.80±2.63 mmHg, and the eyes with disease was 5.00±3.47mmHg,there was sta-tistically significant(P0.01) between them. After glucocorticoid treatment for 7~10days, means IOP of the disease eyes rose to 7.83±2.93 mmHg, higher than before with statistically significant (P0.01). At 1 week and 1,3,6 months postoperatively, the mean IOP of all patients′ disease eyes was much higher than the IOP at 1 day preoperatively(P0.01); the IOP at 1 month postoperatively was lower than the IOP at 1 week postoperatively(P0.05); among 1,3 and 6 months, there were not statistically significant(P0.05).2. At the mo-ment of diagnosis, the mean axial length of all patient’s health eyes was 27.36±2.41mm mmHg, and the eyes with disease was 25.26±2.29 mm. After 7~10 days′ glucocorticoid treatment, the mean axial length of disease eyes was 25.26±2.02 mm, there was not statisti-cally significant (P0.01) relative to before. In the operation of scleral encircling and buckling group, the mean axial length of disease eyes at 1 week,1 month,3 months and 6 months postoperatively were much longer than 1 day preoperatively(P0.01), but it got shorter from 1 week postoperatively(29.46±2.12 mm) to 6 months postoperatively (28.29±2.63 mm), there was statistically significant(P0.01). In the operation of vitrectomy and scleral encircling and buckling group, the mean axial length of disease eyes at 1 week、1 month、3 months and 6 months after the operation of silicone oil removal were much longer than 1 day before operation of retinal replacement(P0.01). there was not statistically significant(P0.05) from 1 week (27.74±2.07 mm) after silicone oil removal to 6 months (27.72±2.17 mm) after silicone oil removal. 3. There was linear correlativity between the IOP difference between two eyes in patients with choriodal detachment associated with retinal detachment and the disease course before treatment. Conclusions: 1. To choroidal de-tachment associated with retinal detachment, the IOP of disease eyes get low, axial length becomes shorter .2. IOP would decrease along with the course of diseases before treatment. 3. Using glucocorticoid before surgery could improve state of illness increased IOP 4. After successful operation of scleral encircling and buckling, the IOP and axial length increase, and axial length shorten during the following 6 months, IOP decrease during the following 1 month, IOP gets steady after 1 month of the operation. After operation of silicone oil re-moval, IOP and axial length are increased than operation of vitrectomy and scleral encircling and buckling. Axial length has little change from 1 week to 6 months after the operation of silicone oil removal, IOP decrease a little during the first 1 month after the operation of silicone oil removal, and gets steady along with the time.
Vogt–Koyanagi–Harada disease
Cite
Citations (0)
Objective: The aim of this study was to report and compare the anatomic and functional results of primary vitrectomy with and without 360° encircling scleral buckle (SB) for the treatment of rhegmatogenous retinal detachment (RRD) due to inferior retinal break(s). Background: A variety of options, including SB, pars plana vitrectomy (PPV) with or without SB, and pneumatic retinopexy have been described as methods to repair RRDs. The use of additional SB with vitrectomy for RRD associated with inferior breaks has been a recent controversy after the introduction of transconjunctival cannula systems. Patients and methods: A retrospective, interventional, comparative case study was performed. In this study, we reviewed 105 consecutive patients who underwent vitrectomy for primary RRD with inferior retinal break(s) at the vitreoretinal center, performed by a single surgeon. Ninety four patients (94 eyes) were followed up for at least 4 months after silicon oil removal (SOR), and were analyzed. They were divided into two groups: group I included 50 patients who underwent PPV alone + silicon oil (SO); and group II included 44 patients who underwent PPV with 360° SB + SO. The essential parameters were single-operation success rate (SOSR) before SOR, incidence of retinal redetachment after SOR, and final visual acuity. Results: SOSR was obtained in 89 eyes (47 [94%] in group I and 42 [95.5%] in group II). From overall 59 phakic retinal detachments (RDs), SOSR was obtained in 56 eyes (30 in group I [93.8%] and 26 in group II [96.3%]) while from overall 35 aphakic or pseudophakic RDs, SOSR was obtained in 33 eyes (17 in group I [94.4%] and 16 in group II [94.1%]). Retinal redetachments after SOR occurred in three patients in group I and two patients in group II. Visual acuity improvement was greater in group I than in group II before SOR. Conclusion: Both surgical procedures had similar reattachment rates. The addition of 360° SB to PPV + SO might not have additional benefits in patients with RD due to inferior retinal break. Keywords: pars plana vitrectomy, scleral buckle, rhegmatogenous retinal detachment
Scleral buckle
Buckle
Cite
Citations (7)
Irregularities in retinal shape have been shown to correlate with axial length, a major risk factor for retinal detachment. To further investigate this association, a comparison was performed of the swept-source optical coherence tomography (SS OCT) peripheral retinal shape of eyes that had either a posterior vitreous detachment (PVD) or vitrectomy for retinal detachment. The objective was to identify a biomarker that can be tested as a predictor for retinal detachment. Eyes with a PVD (N = 88), treated retinal detachment (N = 67), or retinal tear (N = 53) were recruited between July 2020 and January 2022 from hospital retinal clinics in South Australia. The mid-peripheral retina was imaged in four quadrants with SS OCT. The features explored were patient age, eye axial length, and retinal shape irregularity quantified in the frequency domain. A discriminant analysis classifier to identify retinal detachment eyes was trained with two-thirds and tested with one-third of the sample. Retinal detachment eyes had greater irregularity than PVD eyes. A classifier trained using shape features from the superior and temporal retina had a specificity of 84% and a sensitivity of 48%. Models incorporating axial length were less successful, suggesting peripheral retinal irregularity is a better biomarker for retinal detachment than axial length. Mid-peripheral retinal irregularity can identify eyes that have experienced a retinal detachment.
Posterior vitreous detachment
Retinal Tear
Retinoschisis
Cite
Citations (1)
AIM: To comprehensively analyze the risk factors of rhegmatogenous retinal detachment (RRD) associated with choroidal detachment (CD). METHODS: A total of 265 eyes of 265 consecutive cases of RRD were retrospectively analyzed. All patients had systemic and ophthalmologic examination. CD was diagnosed by indirect ophthalmoscopy, B-scan ultrasonography, and ultrasound biomicroscope (UBM). Each parameter was compared between patients of RRD and rhegmatogenous retinal detachment associated with choroidal detachment (RRDCD). Logistic regression analysis was used to determine the independent risk factors of CD. RESULTS: There were 52 eyes (19.62%) with CD. Pseudophakia was more commonly seen in RRDCD (21.15% vs 6.10%, P=0.002). Intraocular pressure (IOP) was lower (8.60±3.62 vs 12.96±3.55, P<0.001), best-corrected visual acuity was worse [3.00 (2.00 to 3.00) vs 1.92 (1.22 to 3.00), P=0.001], and refractive error was more myopic [-4 (-9 to -2) vs -2 (-6 to 0), P=0.007] in RRDCD. Eyes with RRDCD had larger extent of retinal detachment (P=0.007). In RRDCD, 34.62% of eyes presented with multiple holes (P=0.044) and 25.00% with macular holes (P=0.012), compared with 20.66% and 14.08% in RRD. High myopia (P=0.039), low IOP (P=0.017), and larger extent of retinal detachment (P<0.001) were significant and independent risk factors for developing CD. CONCLUSION: For CD in RRD, related factors include BCVA, IOP, lens status, refractive error, extent of retinal detachment, number of holes, and macular hole. Larger extent of retinal detachment, high myopia, and low IOP are significant and independent risk factors.
Pseudophakia
Cite
Citations (27)
To investigate the outcome after combined phaco-vitrectomy in rhegmatogenous retinal detachment (RRD) repair.In this retrospective study, we included all patients who underwent pars plana vitrectomy (PPV) for RRD between January 2013 and December 2017. The main outcome measure was the retinal re-detachment rate after combined phaco-vitrectomy.Overall, 1017 eyes with RRD were included. All eyes received PPV, while in 516 eyes additional phacoemulsification was performed. A retinal re-detachment occurred in 103 patients (10.1%). No significant difference in the rate of re-detachment was found if additional phacoemulsification was performed (p=0.641). Subgroup calculations showed a significant higher rate of re-detachment in patients with a PVR (p=0.0003) and in patients where silicone oil was used as primary tamponade (p=0.0001) as well as in macula off RRDs (p=0.034).Additional phacoemulsification during vitrectomy for RRD is not associated with higher rate of retinal re-detachment.
Cite
Citations (21)
The nationally-recognized Susquehanna
Chorale will delight audiences of all
ages with a diverse mix of classic and
contemporary pieces. The ChoraleAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂA¢AÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂs
performances have been described
as AÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂA¢AÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂemotionally unfiltered, honest
music making, successful in their
aim to make the audience feel,
to be moved, to be part of the
performance - and all this while
working at an extremely high
musical level.AÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂA¢AÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂAÂA Experience choral
singing that will take you to new
heights!
Cite
Citations (0)