Clinical Characteristics and Coronary Angiographic Findings in Patients with Coronary Heart Disease and Type 2 Diabetes Mellitus
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Objectives To study clinical and coronary angiographic findings in patients with both coronary heart diseases (CHD) and type 2 diabetes mellitus (T2DM). Methods 215 patients with CHD confirmed by coronary angiography were involved in this study. The patients were divided into two groups: 74 CHD patients with T2DM ( mean age 64.7 ±8.2 years, male/female 47/27), and 141 CHD patients without T2DM (mean age 66.2 ± 9.2 years,male/female 100/41 ). The clinical features and the data from selective coronary angiographies were compared between type 2 diabetic and non - diabetic CHD patients. Results Compared to non -diabetic CHD patients, the patients with both CHD and T2DM suffered more from acute myocardial infarction, silent ischemia and severe arrhythmias (P ＜ 0. 01, P ＜ 0. 05 ) ,and had higher serum triglycerides and apo - lipoprotein B, along with increased serum uric acid (P ＜ 0. 01, P ＜0. 05), increased left ventricular end diastolic diameter (P ＜ 0. 01 ), and decreased left ventricular ejection fraction ( P ＜ 0. 001 ). Compared to non - diabetic CHD patients, the patients with both CHD and T2DM suffered more from triple vessel disease ( P ＜ 0. 01 ) ,severe coronary artery stenosis, complete occlusions and diffuse lesions ( P ＜ 0. 001 ). Conclusions Severe clinical manifestation, left ventricular dysfunction,diffuse or complicated lesions of coronary arteries were more common in patients with both CHD and T2DM, it suggests that the type 2 diabetic CHD patients have poor prognosis.Cite
Objective:To expore and analyze the clinical characteristics of coronary heart diseases(CHD)combined with type 2 diabetes mellitus(DM).Methods:100 cases of CHD combined with type 2 DM was selected as observation group and 100 cases of CHD as control group.The clinical symptoms,the coronary lesions,the levels of blood sugar and blood lipid were compared between two groups.Results:Compared with group with CHD,①The clinical symptoms was atypical,showing silent heart ischemia and heart dysfunction in obserevation group;②the levels of TG and LDL-C was markedly increased and the level of HDL-C decreased in obserevation group;③most cases showed obstructive and diffusive lesions in multiple branches in obserevation group.Conclusion:The CHD combined with type 2 DM is apt to heart failure.The severity of coronary lesions increased with the level of blood lipid.
Blood sugar
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Objective To investigate the clinical and coronary angiographic features in patients with type 2 diabetes mellitus(CD) combined with coronary heart disease. Methods A total of 143 patients confirmed by coronary angiography were divided into two groups according to they were combined with type 2 DM or not.Of them 75 were type 2 DM without coronary heart disease and 68 only with coronary heart disease.The clinical features including height,weight,BMI,blood pressure,plasma lipids were investigated,and the coronary features were obtained by coronary angiography. Results Higher triglyceride and lower high-density lipoprotein cholesterol and abnormal blood pressure were found in the group of type 2 DM plus coronary heart disease compared with control group,and showed significant difference between both groups (P0.05).The result of coronary angiography showed that patients with type 2 DM combined with coronary heart disease suffered from severe coronary lesions and severe stenosis of coronary artery. Conclusion Blood lipid disorder is mainly found in patients with type 2 DM combined with coronary heart disease and plays an important role in the severity of coronary artery lesions.Severe coronary lesions are found in type 2 diabetes mellitus combined with coronary heart disease.
Coronary atherosclerosis
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Objective: To investigate the clinical and coronary angiographical characteristics in coronary heart disease(CHD) with type 2 diabetes mellitus(T2DM). Method: The clinical features and the date from selective coronary angiographies were compared between the CHD patients with and without T2DM. Result: The major risk of atherosclerosis(hyperlipidemia,hypertension,smoking) and myocardial infarction were similar in two groups.To the proportion of damaged vascular,the three branch damages and polysegment damages,the diabetes group has a statistical significance than nondiabetes group. Conclusion: The CHD patients with T2DM have much great extent of coronary artery involvement and more diffusing vascular.
Hyperlipidemia
Coronary atherosclerosis
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Objective To investigate the characteristics of clinical and coronary artery lesions in type 2 diabetes mellitus(DM) patients with coronary heart disease(CHD).Methods To analyse the clinical expression and coronary angiographic results of 229 DM patients with CHD and 793 non-diabetic patients with CHD.Results DM patients had much more cardiovascular risk factors,including hypertension,high triglyceride,smoking in women and silent ischemia than those in non-diabetic CHD patients.In the pathological changes of coronary artery,the rates of branches coronary artery lesions,the diffuse vascular lesions,small vessel lesions,single lesions in DM group were all markedly different from those in controls( P 0.01).Conclusion The clinical and angiographical characteristics are significantly different in the two groups.The characteristics of coronary angiogram in DM patients with CHD have more multivessel lesions and higher rate of type C lesions,the coronary disease has much small vessels and complex lesions.
Coronary atherosclerosis
Coronary arteries
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Objective To observe the angiography characters of patients with coronary heart disease(CHD) accompanied with type 2 diabetic. Methods Angiogrphy data of 107 CHD patients accompanied with type 2 diabetes and 677 CHD patients without diabetes were statistically analyzed.Results The angiography characters between the two groups are significantly different. Multiple branches involvement, left main coronary artery lesions, numbers of coronary arteries involved and diffusive lesions in diabetic patients are significantly higher than those in the another group. Though the closure artery number is a little bit higher in diabeties patients than in those without diabetes, but it does not reach statistical significance. Conclusion The involvements of coronary arteries in coronary heart disease with diabetes are more severe than in coronary heart disease without diabetes.
Coronary arteries
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Objective To investigate the risk factors and characteristics of coronary artery lesion in patients with coronary heart disease with diabetes mellitus Ⅱ.Methods 596 patients with coronary heart disease(CHD) included them with diabetes mellitus(DM group,n=130) and them without diabetes mellitus(No-DM group,n=466).The data of coronary arteriography and the related risk factors including FPG,TC,TG,smoking,HDL-C,LDL-C and UA were compared between two groups.Results TG and HDL-C were significantly higher in CHD with DM group than those in CHD without DM group(P0.05).The data of coronary arteriography showed more severe and more-vessel lesions in the CHD with DM group than those in CHD without DM group(P0.05).Conclusion The severity of coronary artery lesion related with the amount of risk factors in CHD with DM.
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Objective:To research the relationship between coronary artery lesions and lipid metabolic disorder of coronary heart disease(CHD) with diabetes mellitus(DM).Methods Results Conclution Methods:we have Observed the characteristics of coronary angiography and blood lipids level in CHD with and without type 2 DM patients,the analysis was done by combining the results with the clinical aspects.Results: The blood cholesterol(TC) level and LDL-C are remarkably higher,three branches lesions and diffused lesions of coronary artery increased significantly in CHD with type 2 DM patients than CHD without DM patients(P0.05).Conclusions: The CHD can be prevented and delayed if type 2 DM are treated effectively and the risk factors of CHD such as hyperglucamia hypertension hyperlipdemia and overweight are controlled nicely.
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Objective To summarize the clinical and angiographic characteristics of patients with coronary heart disease (CHD)complicated with type 2 diabetes.Methods 106 patients with CHD complicated with type 2 diabetes and 450 patients not complicated with type 2 diabetes were studied by case-control methods, whose risk factors, blood lipids and coronary angiogram were analyzed.Results Compared with patients with CHD not complicated with type 2 diabetes, more female patients were found in patients complicated with type 2 diabetes, the prevalence of hypertension and dyslipidemia was significantly higher. Blood triglyceride concentrations was raised, while blood high density lipoprorein-cholesterol concentrations was decreased. More multi-vessel diseases[72.64%v.s 56%,P=0.002] were found in patients with CHD complicated with diabetes, whose Gensini scoring was significantly increased(59.3±35.85 v.s 49.37±37.54,P=0.014).Conclusion The CHD patients complicated with type 2 diabetes are more female,and easily clustering risk factors, whose coronary lesion is more severe.
Dyslipidemia
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Objective: To study the angiographic characteristics of type 2 diabetic patients with coronary heart disease(CHD).Methods: Angiographic data of 78 CHD patients with type 2 diabetes and 136 CHD patients without diabetes were statistically analyzed.Results: Numbers of coronary arteries involved,multiple branches involvement and diffusive lesions in diabetic patients with CHD are significantly higher than those in the another group.Conclusion: The involvement of coronary arteries in CHD with diabetes are more severe than in CHD without diabetes.
Coronary arteries
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Objective To study the clinical manifestations and coronary artery disease features in coronary heart disease(CHD) patients with type 2 diabetes mellitus(DM).Methods 148 patients with coronary heart disease diagnosed by coronary angiography were involved in the present study,in which 70 patients with DM as the observation group and 78 patients without DM as the control group.The clinical characters and coronary angiographic features were analyzed.Results Age,sex,hypertension,hyperlipidemia and smoking history had no significant difference between two groups(P0.05).The TG,LDL-L levels in the observation group were significantly higher than the control group,and the HDL-L level is significantly lower(P0.05),the coronary artery lesions of observation group is dominated by multi-vessel disease and diffuse lesions,the stenosis is severe(P0.05).Conclusion Dyslipidemia is more pronounced in patients with coronary heart disease and type 2 diabetes mellitus,the characteristics of coronary artery lesions is multi-vessel,widespread and diffused.
Dyslipidemia
Hyperlipidemia
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