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    Detecting oxygen changes in the lungs
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    Abstract:
    Lung airway basal stem cells directly sense changes in oxygenation, driving lung regeneration
    Keywords:
    Basal (medicine)
    This review discusses the origin of the regeneration blastema, and particularly the importance of the skin, the skeleton, and other tissues in the process of regeneration. Also considered are reactions of regenerates to irradiation, including the effect of partial irradiation and the regression of regenerates. Especial attention is given to regeneration under abnormal conditions and to abnormal regeneration. The final section is concerned with the problem of stimulation of regeneration and the possibilities of regeneration in mammals.
    Blastema
    Skeleton (computer programming)
    Citations (14)
    This paper is concerned with methods of regeneration: morphallaxis, epimorphosis, and regeneration by induction. The last method was demonstrated by investigations to study the restoration of lost regenerative power of the cranial bones in adult dogs and in some other cases. During regeneration by induction an inducing agent, reactive or competent material, and the right conditions for induction must be present. It is emphasized that the method and mechanism of regeneration are one and the same thing. The methods of regeneration specified above differ not only in their formal and secondary features, but also in the essence of their fundamental processes: true reorganization, growth, and induction. Each method of regeneration can be found not only in the pure form, but also in combinations of varying degree and type. Besides regeneration, hypertrophy is also very important for the restoration of parenchymatous internal organs in mammals, but it is not identical with regenerations.
    Compensatory hypertrophy
    Citations (1)
    The changes in autogenous lung oxygenation and artificial lung during cardiopulmonary bypass (CPB) were compared. The results of our investigation showed that autogenous lung oxygenation is less injurious to the lung than bubble oxygenation and is more physiological. We think that during autogenous lung bypass and open heart surgery, the lung is functioning physiologically and is supplied with normal amount of oxygen, while using bubble oxygenation for CPB the native lung is the only nonperfused organ and lung function being insulted by pulmonary ischemia which is one of the most important reason for pulmonary injury after CPB.
    Artificial lung
    Citations (0)
    Nerve regeneration is a process of self-recovery after nerve injury. Nerve regeneration is more difficult in the central nervous system (CNS) than in the peripheral nervous system (PNS). So far, there are few cases of CNS cure. The difficulty of CNS regeneration brings great loss to patients and society. In recent years, scientific research has found that damage to the CNS is caused by mechanisms that hinder its regeneration. This review has provided a comprehensive summary of recent studies on the inhibitory mechanism of glial scar, which are the main factors affecting axonal regeneration in the CNS, and deeply discussed the mechanism of a series of factors related to glial scar, such as CSPGs, Nogo family proteins, NgR1, LINGO-1 and p75, on the production of glial scar. After this, the idea of their ability to study the regeneration of the CNS after injury was analyzed, and the new technology of anti-inhibition of CNS regeneration therapy was looked forward.
    Glial scar
    Peripheral Nervous System
    Citations (0)