White esophageal lesions in a patient with scleroderma: epidermoid metaplasia
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Keywords:
Scleroderma (fungus)
Metaplasia
White (mutation)
Objective Currently, little material is available for esophagus reconstruction and the survival rate within perioperative period is low in animal experiments in the literature. This study assesses the feasibility of esophagus reconstruction with biological artificial esophagus in dogs. Methods The biological artificial esophagus and 30 Chinese mongrels were used as experimental materials. Part of the thoracic esophagus of dogs were resected, then 8 cm length biological artificial esophagus were implanted to reconstruct the esophagus. The surviving and eating, as well as healing process were observed. Results Among the 30 dogs, 28 dogs were survived after perioperative period,the survival rate was 93.3%. The anastomotic leakage was found in 2 dogs(6.67%). Nineteen dogs were survived for one year, and the survival rate was 79.2%(19/24, 6 dogs were killed according to the experimental protocol). The average time of exfoliation of biological artificial esophagus was 28.8 days. The dysphagia was occurred 23 to 45 days, and 2 months after operation, however, it can be remitted by itself after 4 months. The histology showed that the regenerated esophagus was consisted of fibrous and connective tissue, and the luminal surface of regenerated esophagus was coverd with squamous epithelium within 3-6 months. Conclusions The “new esophagus” was regenerated after the operation of esophagus reconstruction, and the biological artificial esophagus would exfoliate. While the regenerated esophagus mould, the stenosis was relieved by itself. To solve the exfoliation of artificial esophagus and stenosis after operation is the key for the biological artificial esophagus to be used in clinics.
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To compare the diagnosis and therapeutic between chest computed tomography three-dimensional reconstruction and esophagus barium swallow in esophagus foreign body.retrospective analyze one hundred and thirty six patients who suffered from esophagus foreign body in our hospital, 97 cases using esophagus barium swallow, 17 cases using chest computed tomography three-dimensional reconstruction, 15 cases using both.The patients who showed positive of esophagus foreign body in esophagus barium swallow or chest computed tomography three-dimensional reconstruction, 91.8% (89/97) cases or 88.2% (15/17) cases found esophagus foreign bodies finally. All cases successfully took out the esophagus foreign bodies only through one operation which used chest computed tomography three-dimensional reconstruction as primary examination, while only 91.0% for those used esophagus barium swallow as primary examination.Both chest computed tomography three-dimensional reconstruction and esophagus barium swallow showed high diagnostic efficiency on esophagus foreign body. Chest computed tomography three-dimensional reconstruction had advantages in patients with one of following conditions: (1) esophagus foreign body located in the middle of the esophagus, especially complicated with esophagus perforation; (2) with fever, high white blood count, presence of abscess surrounding the esophagus was suspected; (3) with dyspnea; (4) with a history of esophagus foreign body longer than 5 days; (5) younger than 6 years old.
Perforation
Barium sulfate
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Objective To discuss the X-ray features of esophagus small cell carcinoma.Methods30 cases with fully clinical and X-ray examination data,which were confirmed byoperation and pathology,were studied retrospectively.ResultsOf 30 patients,27 were maleand 3 were female.The age ranged from 36～66 years old.The average age was 55. In X-ray plain film,the lesions of 23 cases located in the middlepiece of esophagus,and 7 in the lowersegment of esophagus.The cancer cell of 11 cases erosioed muscular layer of esophagus,and19 erosioed adventitia of esophagus.In the following-up of 20 patients, 16 died in 1year.ConclusionEsophagus small cell carcinoma usullary occur in the middlepiece or lowersegment of esophagus, of which clinical manifestations and X-ray signs are similar to the othertypes of esophagus carcinoma. Esophagus small cell carcinoma is of high malignant, shortcourse of disease, growth quickly and easy to transfer. Early diagnosis, performing operation,systematic chemical therapy and radiation therapy are helpful to good prognosis.
Adventitia
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Granular cell
Epidermoid carcinoma
Granular Cell Tumor
Esophageal disease
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Introduction
An operation will be presented which enables the entire esophagus to be replaced, from the pharynx to the cardia of the stomach. The procedure has been used successfully in the treatment of benign and malignant obstructions of the esophagus. Gastrointestinal continuity is restored physiologically. The patient in whom the entire esophagus has been resected or by-passed by a reversed gastric tube can eat all foods in a normal manner. The operation will be described and three case reports presented which illustrate its use in the treatment of benign and malignant esophageal obstructions. I have performed this operation in 10 consecutive patients, 2 of whom will be presented. The first case demonstrates the successful treatment of carcinoma of the upper thoracic esophagus. The second report describes the restoration of gastrointestinal continuity in a patient with a lye stricture of the esophagus. I described the reversed gastric tube operation in 1955,Cite
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Objective: To study the expressions of CyclinD1, TGF-β1 and GST-π in squamous cell carcinoma of esophagus, and their effects on the growth of human squamous cell carcinoma of esophagus. Methods: Eighty-one specimens of human squamous cell carcinoma of esophagus and 43 normal esophagus as control were assessed by immunohistochemical method (SP method). Result: The positive expression rate of CyclinD1, TGF-β1 and GST-π in squamous cell carcinoma of esophagus was higher than that in normal esophagus. The positive expression rate of CyclinD1, TGF-β1 and GST-π were higher by lymphatic metastasis grades than no lymphatic metastasis grades. Conclusion: CyclinD1, TGF-β1 and GST-π have more significant differences in squamous cell carcinoma of esophagus than normal esophagus.They play an important role in development of squamous cell carcinoma of esophagus. They would be helpful in diagnosis of squamous cell carcinoma of esophagus, especially GST-π may act as an early maker.
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Basic investigation on the intraluminal pressure of the esophagus and its clinical applications are carried out, and also cinefluoroscopy of the esophagus and pH. changes of content of the esophagus are investigated.1) Method: The intraluminal pressure is measured by means of Opentip Method and a) the resting pressures, b) pressures during primary and secondary peristalsis are recorded.Investigations on c) the intraluminal temperature, d) pH., e) E. M. G. f) pneumography are also employed.2) Results: The patterns of the pressure curve during deglutition in different parts on the lumen of the esophagus are obtained. There are many characteristics of the patterns of the curve in various pathological states such as achalasia, diffuse spasm or cancer of the esophagus.3) Conclusion: Measurement of the intraluminal pressure of the esophagus is as valuable method as roentgenology and esophagoscopy for observation of the dynamic action of the esophagus and for diagnosis of diseases of the esophagus.
Peristalsis
Lumen (anatomy)
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