[Association between hypertriglyceridemic waist?to?height ratio phenotype and chronic kidney disease in a community population in South China: a cross-sectional study].
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To investigate the relationship between hypertriglyceridemic waist to height ratio phenotype (HWHtR) and chronic kidney disease (CKD) in a community population in South China.A cross sectional study was conducted among 2142 residents in Zhuhai (Guangdong Province, China) from June to October of 2012. The HWHtR phenotype was defined as a waist to height ratio(WHtR) ≥0.55 and triglyceride level ≥2.0 mmol/L, based on which the participants were divided into HWHtR group and nonHWHtR group. CKD was defined as an eGFR<60 mL/min per 1.73 m2 or an ACR ≥30 mg/g. A logistic regression model was established to investigate the relationship between chronic kidney disease and HWHtR phenotype.Compared with the nonHWHtR group, the HWHtR group had a higher prevalence of chronic kidney disease (11.1% vs 33%, P<0.001). Analysis using the logistic regression model showed that HWHtR was significantly associated with CKD in the unadjusted analyses (OR=3.23, 95% CI: 2.32-4.48, P<0.001). After adjustment for age, sex, history of hypertension, history of diabetes, systolic blood pressure, diastolic blood pressure, drinking, physical exercise, education and current smoking, HWHtR was significantly associated with CKD (OR=2.36, 95% CI: 1.52-3.67, P<0.001); the association of HWHtR and CKD was still significant after further adjustment for BMI (OR=2.12, 95%CI: 1.34-3.35, P<0.001).Our finding suggests that HWHtR is associated with CKD in this community population.Keywords:
Cross-sectional study
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Purpose: Obesity and overweight are associated with variety of conditions detrimental to health, wellbeing and longevity. Waist circumference and waist to hip ratio are indicators of risk of central adiposity while body mass index is an indicator of overall risk of obesity. Body mass index has been traditionally used as a standard for determining overweight and obesity. This study was designed to determine the relationship between waist circumference, waist to hip ratio and body mass index among female undergraduates of a Nigerian University. Also prevalence of obesity based on waist circumference, waist to hip ratio and body mass index was explored. Methods: Three hundred and sixty four apparently healthy subjects were recruited for the study using a cross-sectional simple random sampling technique. Waist circumference, waist to hip ratio and body mass index were determined using standard methods. Descriptive statistics were used to summarize the physical characteristics of the participants. Pearson correlation coefficient was used to analyze the relationship between waist circumference, waist to hip and body mass index. Results: The mean age, waist circumference, waist to hip ratio and body mass index of the participants were 22.5 (±2.20) years, 79.36 (±10.4) cm, 0.81 (±0.06), and 22.48 (±4.50) kg/m2 respectively. The prevalence of obesity based on body mass index, waist circumference and waist to hip ratio was found to be 6.3%, 17.6% and 25.5% respectively. Significant relationship was found between waist circumference and body mass index (r = 0.81; p< 0.001), and between waist to hip ratio and body mass index (r = 0.25; p< 0.001). Conclusions: Body mass index was related to waist circumference, as well as to waist to hip ratio. The prevalence of obesity based on waist to hip ratio was highest among female undergraduates in a Nigerian university. Awareness on the importance of waist to hip ratio as indicator of risk of obesity should be created among female undergraduates in Nigerian Universities and by extension among the women population in general.
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The aim of the study was to assess the relationship between age and obesity, to assess waist circumference and obesity. This type of quantitative research uses a cross-sectional design. The sample is 161 respondents. Data was collected using a questionnaire and measuring body mass index. Data were analyzed using the Pearson correlation test and linear regression analysis. The results showed that there were 144 respondents (89.4%) in the 18 - 25 year age category, 13 respondents (8.1%) for Body Mass Index for the first obesity category, 12 respondents (7.5%) for obesity II. There is a relationship between age and waist circumference with a p-value of 0.0001, there is a relationship between age and body mass index with a p-value of 0.0001. There is a relationship between age and body weight with a p-value of 0.001. Age is a risk factor for waist circumference, BMI, weight and hearing. As you get older, your waist circumference increases, your BMI increases, your weight increases and your age decreases your hearing ability. An obesity risk factor is age
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Objective: This study was carried out on different populations of genetic and physical conditions to confer the relationship between genetic polymorphisms and the body mass index(BMI) and waist circumference(WC).And on this basis,this study observes the impact of the changes of FTO gene polymorphism of people with different levels of physical activity on the body mass index(BMI) and waist circumference(WC),so as to understand the interaction of genetic and environmental effects on physical condition,and provide theoretical guidance of developing physical health research.Method: The FTO variant rs1121980 was genotyped in 20,774 participants(39~79 y of age) from the Han population in Northern China,an ethnically homogeneous population based cohort physical activity(PA) was assessed with a validated self reported questionnaire.The interaction between rs1121980 and PA on body mass index(BMI) and waist circumference(WC) was examined by including the interaction term in mixed effect models.Result: It confirmed that the risk(T) allele of rs1121980 was significantly associated with BMI and WC.The PA level attenuated the effect of rs1121980 on body mass index(BMI) and waist circumference(WC);Conclusion: the results showed that PA attenuates the effect of the FTO rs1121980 genotype on body mass index(BMI) and waist circumference(WC).This observation has important public health implications because it shown that a genetic susceptibility to obesity induced by FTO variation can be overcome,at least to some extent,by adopting a physically active lifestyle.
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Risk of cardiovascular diseases increases in Asian adults within the normal limits of body mass index and waist circumference.To determine a point of body mass index and waist circumference above which the chances of having cardiovascular risk factors increased.Data on anthropometric indices, blood pressure and biochemical measures were collected in a cross-sectional study of 3447 participants (1781 males and 1666 females) with normal body mass index (19 to <25 kg/m for both sexes) and normal waist circumference (<102 cm for men and <88 cm for women). Metabolic abnormalities were defined on the basis of the standard published criteria.Individuals at the highest category of body mass index (24 to <25 kg/m) had significantly higher odds for having metabolic risk factors (odds ratios ranging from 1.3 to 1.6 for men and 1.36 to 2.0 for women for different risk factors) compared with those at first category (19 to <20 kg/m). Furthermore, individuals at the top category of waist circumference (95 to <102 cm for men and 85-88 cm for women) had significantly higher chances of having metabolic abnormalities (odds ratios ranging from 2.6 to 4.5 for men and 2.1 to 2.6 for women for different risk factors) compared with those in the first category (62 to <70 cm for men and 60 to <65 cm for women) in both sexes.We concluded that the cut-off points of body mass index and waist circumference suggested by the World Health Organization are inappropriate for the Tehranian urban population.
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This article outlines the clinical values and limitations of body mass index and waist circumference for nutritional assessment among obese individuals and emphasizes the importance of combining these two parameters for diagnosis of obesity.
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Objective: It has been reported in coronary heart disease (CHD) patients that mortality is inversely associated with body mass index (BMI), and directly associated with waist circumference (WC). The purpose of this study was to examine the association of the general obesity parameter (BMI) and the adipose tissue discriminator (WC) with cardiovascular risk in patients with CHD established by coronary angiography. Design and method: To the PROGNOSIS (Prognostic Value of Ambulatory Blood Pressure Monitoring in Patients with Coronary Artery Disease Confirmed by Angiography) study there were included 1345 subjects with CHD. A multivariate COX proportional regression model adjusted for potential confounders was used to assess the relative risk of total and CV mortality according to the parameters of general obesity (BMI) and adipose tissue distribution (WC). The mean age of subjects was 63.2 ± 9.2 years, and 57% were men. Results: There was direct relationship between WC and both total mortality (HR 1.03 (CI 1.01–1.10), p < 0.01) and CV mortality (HR 1.03 (CI 1.01–1.07), p < 0.03), but an inverse relationship between BMI and both total mortality (HR 0.91 (CI 0.86–0.98), p < 0.03) and CV mortality (HR 0.97 (CI 0.87–0.99), p < 0.05). After combining WC with BMI, the group of subjects with BMI <25 kg/m2 and WC >=104 cm had the highest rates of both total and CV mortality of all CHD patients. Conclusions: Assessment based on a combination of WC and BMI is superior to assessment based on a separate estimation of these parameters in both total and CV mortality risk evaluation.
Obesity paradox
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Objective:This study was carried out on groups of different physical condition,exploring the relationship between changes of gene polymorphism and BMI(body mass index)and WC(waist circumference).And on the basis it explores the effect of different levels of physical activity on BMI and the crowd WC.Method:The Han population in northern China in the subjects(age 39~79 years) were assessed for physical activity(PA),and the subjects(subjects are from the same ethnic group)height,weight,waist circumference and other indices were measured.Effects of physical activity on body mass index and waist circumference(WC) were analyzed.Conclusion:The physical activity significantly reduced the effects on BMI and WC.The effect of BMI and WC of the inactive group is greater than the active group.The findings have great in promoting significance public health,which shows that the increase in body mass index and waist circumference can be controlled lifestyle physical activity.
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Abstract Body mass index (BMI) is typically used to define overweight and obesity. However, without waist circumference information, BMI may misclassify as overweight or obese. Therefore, we proposed a new index based on BMI. We developed a New Body Mass Index (NBMI) by adding waist circumference (WC) to BMI, which combined BMI and WC. That is, it also combined weight-for-height and waist-to-height ratios. The formula is: NBMI = BMI × WC (m) = WT (kg) / HT (m 2 ) × WC (m) = WT (kg) / HT (m) × WC (m) / HT (m) = weight-for-height × waist-to-height. Firstly, individuals with the same height and weight have the same BMI, but their waist circumferences could vary considerably, and NBMI could distinguish body differences among people's waist sizes. Secondly, NBMI could better identify central obesity than BMI. Thirdly, NBMI could not only measure body mass but also classify health and obesity degrees according to a wide range of scores. Firstly, NBMI incorporating WC could better reflect the body difference in waist size than BMI. Secondly, NBMI is more convenient for identifying central obesity. Thirdly, NBMI could better classify different weight types by expanding the score range.
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In today’s world limited data are available on adolescent obesity regarding the better predictor among various parameters of anthropometric parameters. The aim of this study was to investigate whether there is a correlation between the obesity and anthropometric parameters such as Body mass index, waist circumference, waist to height ratio and to find out which one is the better predictor of obesity among these parameters. A status study was designed under purposive sampling included 162 school going adolescents in urban areas of the Delhi, India in the year 2013-2014.In this study, the prevalence of obesity and overweight was found between 3.70% and 19.75% respectively. According to waist to height ratio analysis 36.42% and waist circumference 22.83% male adolescents were found obese. Body Mass index, Waist to height ratio and Waist circumference were significantly correlated with each other. It was concluded that waist to height ratio is a better predictor for the obesity than Body mass index and Waist circumference. Keywords : Body mass index, Waist height ratio, Obesity, Adolescents.
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