Game of Tissues: How the Epidermis Thrones C. elegans Shape
15
Citation
116
Reference
10
Related Paper
Citation Trend
Abstract:
The versatility of epithelial cell structure is universally exploited by organisms in multiple contexts. Epithelial cells can establish diverse polarized axes within their tridimensional structure which enables them to flexibly communicate with their neighbors in a 360° range. Hence, these cells are central to multicellularity, and participate in diverse biological processes such as organismal development, growth or immune response and their misfunction ultimately impacts disease. During the development of an organism, the first task epidermal cells must complete is the formation of a continuous sheet, which initiates its own morphogenic process. In this review, we will focus on the C. elegans embryonic epithelial morphogenesis. We will describe how its formation, maturation, and spatial arrangements set the final shape of the nematode C. elegans. Special importance will be given to the tissue-tissue interactions, regulatory tissue-tissue feedback mechanisms and the players orchestrating the process.Keywords:
Multicellular organism
Epidermis (zoology)
Embryonic Induction
Multicellular organism
Model Organism
Biological organism
Cite
Citations (1)
Multicellular organism
Cell type
Model Organism
Cite
Citations (2)
Recent findings prove that anti-aging processes in cells can successfully counteract cellular deterioration. Some researchers agree with the view that the aging of the multicellular organism is rather a function of breakdown in integrative mechanisms than of fatal changes in individual cells. Why, in this case, does an organism composed of potentially ageless cells age? The answer may be found by taking into account the influence of all external factors that induce organisms to function in one physiological regimen or another. The paper shows that the effectiveness of the control systems to self-maintenance may depend not only on organism's structural or functional features but also indirectly on the external conditions in which it exists. It describes some facts that agree with the approach proposed.
Multicellular organism
Model Organism
Cite
Citations (0)
Multicellular morphogenesis is the main content of myxobacterial social behavior. The morphogenesis contains aggregation of cells under nutrient deprivation, autolysis, development of fruiting bodies and formation of myxospores. There is a complicated system of signals and regulation during morphogenesis, which is much more similar to eukaryotes. Myxobacterium is an important model for studying cellular differentiation and development in prokaryotes and biological evolution.
Myxobacteria
Multicellular organism
Autolysis (biology)
Cite
Citations (1)
This chapter follows up in more detail the topic of symbiosis introduced in Chapter 5. Contrary to the common assumption that an organism can be defined by the common genome sequence to be found in all its cells, there is great genomic diversity in multicellular organisms. This is due to various forms of natural or artificial chimerism and genetic mosiacism, and also to the interdependence of the multicellular organism traditionally understood and its multitudes of microbial symbionts.
Multicellular organism
Model Organism
Cite
Citations (3)
The biological success of the multicellular body plan lies in its capacity for tissue differentiation and specialisation of function. Differentiated organs and tissues, in fulfilling their specialised activities on behalf of the whole organism, cannot act autonomously. The functions are co-ordinated (Part V) to provide an integrated response to the needs of the organism. A further feature of the differentiated organism is the presence of a transport system which carries metabolic substrates to the cells of the organism and likewise distributes metabolic products. In animals the transport function is carried out primarily by the blood system and in higher plants by xylem and phloem.
Multicellular organism
Body plan
Cite
Citations (0)
Cite
Citations (1)
Biology lacks a central organism concept that unambiguously marks the distinction between organism and non-organism because the most important questions about organisms do not depend on this concept. I argue that the two main ways to discover useful biological generalizations about multicellular organization—the study of homology within multicellular lineages and of convergent evolution across lineages in which multicellularity has been independently established—do not require what would have to be a stipulative sharpening of an organism concept.
Multicellular organism
Biological organism
Convergent evolution
Model Organism
Homology
Cite
Citations (39)
Multicellular morphogenesis is the main content of myxobacterial social behavior. The morphogenesis contains aggregation of cells under nutrient deprivation, autolysis, development of fruiting bodies and formation of myxospores. There is a complicated system of signals and regulation during morphogenesis, which is much more similar to eukaryotes . Myxobacterium is an important model for studying cellular differentiation and development in prokaryotes and biological evolution.
Myxobacteria
Multicellular organism
Autolysis (biology)
Cite
Citations (0)