Appendiceal tumours and pseudomyxoma peritonei: Literature review with PSOGI/EURACAN clinical practice guidelines for diagnosis and treatment
Kim GovaertsRobin J. LurvinkIgnace H. J. T. de HinghKurt Van der SpeetenLaurent VilleneuveShigeki KusamuraVahan KépénékianMarcello DeracoOlivier GléhenB. MoranPedro Barrios-SánchezJoel BaumgartnerAlmog Ben‐YaacovRossella BertulliPeter CashinTom CecilSanjeev DayalMichele De SimoneJason M. FosterDiane GoèréKuno LehmannYan LiBrian W. LoggieFaheez MohamedDavid L. MorrisAviram NissanPompiliu PisoMarc PocardBeate RauMarc A. ReymondLucas SidérisJohn SpiliotisPaul H. SugarbakerVictor J. VerwaalMalcom S. WilsonYutaka YonemuraYang Yu
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Seperti pada dewasa, teknik regional anestesi pada pediatrik kini makin popular digunakan oleh ahli anestesikarena keuntungannya. Namun demikian selalu ada risiko dan kemungkinan timbulnya komplikasi dari setiap tindakan yang dilakukan, termasuk tindakan anestesi regional pada pediatrik. Insidensi komplikasi anestesi regional pada pediatrik tidak banyak, dan kalaupun terjadi komplikasi adalah minor. Komplikasi bisa diakibatkan dari identifikasi ruang saraf, alat, obat, teknis tindakan anestesi regionalnya dan komplikasi lainnya.Walaupun tidak banyak kejadian komplikasi regional anestesi yang dilaporkan pada pediatrik, dan bukanlah komplikasi yang fatal, teknik regional anestesi pada pediatrik harus dilakukan dengan lebih hatihati, pertimbangan risiko dan keuntungannya untuk menghindari terjadinya komplikasi, terlebih karena kebanyakan komplikasi dapat dihindari dengan mempelajari teknik yang benar, menggunakan peralatan yang sesuai, dan sangat menerapkan prinsip keamanan pada pasien dengan baik.
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Genentech is partnering with the German cancer company Affimed to develop immunotherapies for multiple kinds of solid and blood cancers. Affimed is developing therapies that engage natural killer cells of the innate immune system to help direct them to attack cancer cells. Genentech will pay Affimed $96 million up front and up to $5 billion more in potential payments.
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No AccessJournal of UrologyClinical Urology: Case Report1 Sep 1995Mucinous Cystadenocarcinoma of the Vermiform Appendix Presenting as a Renal Tumor J. Javier Gomez-Roman, J. Fernando Val-Bernal, and Fidel Fernandez J. Javier Gomez-RomanJ. Javier Gomez-Roman More articles by this author , J. Fernando Val-BernalJ. Fernando Val-Bernal More articles by this author , and Fidel FernandezFidel Fernandez More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66994-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail References 1 : 71,000 Human appendix specimens. A final report, summarizing 40 years' study. Amer. J. Proctol.1963; 14: 265. Google Scholar 2 : Adenocarcinoma of the vermiform appendix presenting as a uterine tumor. Gynec. Oncol.1982; 13: 265. Google Scholar 3 : Mucinous tumors of the appendix associated with mucinous tumors of the ovary and pseudomyxoma peritonei. A clinicopathological analysis of 22 cases supporting an origin in the appendix. Amer. J. Surg. Path.1991; 15: 415. Google Scholar 4 : Primary mucinous adenocarcinoma of the appendix with bilateral Krukenberg tumors of the ovary and primary adenocarcinoma of the endometrium. Gynec. Oncol.1984; 19: 358. Google Scholar 5 : Pseudomyxoma peritonei. A clinicopathologic study of 19 cases with emphasis on site of origin and nature of associated ovarian tumors. Amer. J. Surg. Path.1994; 18: 591. Google Scholar 6 : Epithelial neoplasia of the appendix.. In: Pathology of the Colon, Small Intestine, and Anus. Edited by . New York: Churchill Livingstone1983: 223. chapt. 9. Google Scholar 7 : A 25-year review of adenocarcinoma of the appendix. A frequently perforating carcinoma. Dis. Colon Rect.1988; 31: 145. Google Scholar 8 : Peritoneal carcinomatosis from appendiceal cancer: results in 69 patients treated by cytoreductive surgery and intraperitoneal chemotherapy. Dis. Colon Rect.1993; 36: 323. Google Scholar 9 : Kidney. In: Urologic Pathology. Philadelphia: J. B. Lippincott Co.1986: 134. chapt. 1. Google Scholar 10 : Solitary renal metastasis from osteogenic sarcoma. J. Roy. Coll. Surg. Edinburgh1990; 35: 314. Google Scholar 11 : Symptomatic renal metastasis from testicular cancer. Cancer1993; 71: 3979. Google Scholar 12 : CT analysis of metastatic neoplasms of the kidney. Comparison with primary renal cell carcinoma. Acta Rad.1992; 33: 39. Google Scholar 13 : Intraluminal renal metastases from colon cancer simulating a fungus ball. Urol. Rad.1992; 13: 226. Google Scholar 14 : Multiple synchronous primary intra-abdominal neoplasms. J. Natl. Med. Ass.1989; 81: 1177. Google Scholar 15 : Mucocele of the appendix. Sonographic, computed tomographic and radiologic characteristics. Radiologe1990; 30: 15. Google Scholar 16 : Renal manifestations of extrarenal neoplasms. Hum. Path.1980; 11: 7. Google Scholar 17 : Renal tumors in the adult patient.. In: . Philadelphia: J. B. Lippincott Co1994: 1540. chapt. 49. Google Scholar Department of Anatomical Pathology, Marques de Valdecilla University Hospital and Medical Faculty, University of Cantabria, Santander, Spain© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 154Issue 3September 1995Page: 1122-1124 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information J. Javier Gomez-Roman More articles by this author J. Fernando Val-Bernal More articles by this author Fidel Fernandez More articles by this author Expand All Advertisement PDF downloadLoading ...
Vermiform
Pseudomyxoma Peritonei
Mucinous cystadenoma
Mucinous cystadenocarcinoma
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In the past, mucinous appendiceal neoplasms (MAN) greater than 2 cm in diameter were treated by a right colon resection. New data shows that treatment options are to be determined by the histopathologic grade of the appendiceal tumor and the condition of the wall of the appendix (intact vs. breached). A 39-year-old woman had an incidental diagnosis of a low-grade appendiceal mucinous neoplasm (LAMN) at the time of a hysterectomy. The appendiceal tumor had small quantities of mucus surrounding an enlarged appendix. No tumor cells were seen in the mucus by histologic study. The patient was placed in follow-up. Eighteen years later she required treatment for advanced pseudomyxoma peritonei. When 5 different histopathologic types of MAN are considered with an intact vs. perforated wall of the appendix, four different treatment options develop. With LAMN and well or moderately differentiated mucinous appendiceal adenocarcinoma (MACA), the patient does not require operative intervention if the wall of the appendix is intact. If mucus or mucus plus tumor cells are identified outside the appendix an intervention is indicated. In patients, as the one presented, in whom only small amounts of mucus are outside the appendix, surveillance may be recommended. In patients with a diagnosed low-grade MAN, dissemination to regional lymph nodes is rare. Dissemination to the peritoneal space places the patient at risk to develop pseudomyxoma peritonei. As this case report illustrates, if surveillance is recommended, long-term follow-up is required.
Pseudomyxoma Peritonei
Mucinous Tumor
Cystadenoma
Mucinous cystadenoma
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The paper describes a recent case of carcinoid of the appendix in a 15 year old patient, operated for appendicitis. The diagnosis was found incidentally by histologic examination. Following a review of the literature the Authors discuss the epidemiology and clinical aspects of the appendiceal carcinoid, the most common tumour of the appendix.
Presentation (obstetrics)
Carcinoid tumors
Carcinoid tumour
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