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    The local and peritoneal recurrence play a vital role in the natural history of the evolution of gastrointestinal and ovarian neoplasms. Different methods of applying intraperitoneal chemotherapy were used perioperatively to consolidate or control peritoneal carcinomatosis.
    Intraperitoneal Chemotherapy
    Port (circuit theory)
    Cisplatin (100 mg) was given by intraperitoneal infusion to 23 patients with peritoneal carcinomatosis. Eighteen patients had gastric cancer, and five had colorectal cancer. The effects of this therapy were as follows. 1) In gastric cancer patients, the mean survival period was 11.0 months. The cumulative survival rate was superior at the level of statistical significance in comparison with controls. 2) The side effects of this agent given intraperitoneally were mild. In particular, nausea was slightly less than with intravesicular or intraarterial infusion.
    Citations (4)
    The management of peritoneal carcinomatosis from colon cancer remains a controversial issue. Peritoneal carcinomatosis is associated with worse survival and has led to an aggressive treatment that combines surgery and intraperitoneal chemotherapy (IPC). This review will describe the rationale behind this treatment and the current controversy surrounding it.
    Intraperitoneal Chemotherapy