Association between oral health status and chronic obstructive pulmonary disease in Korean adults
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Objective: To explore the clinical features of chronic obstructive pulmonary disease(COPD) complicated by spontaneous pneumothorax. Methods:We analyzed retrospectively the data of 87 patients with COPD complicated by spontaneous pneumothorax who were treated in our hospital during last 8 years. Results:Among those patients,the diagnosis of 45 cases(51.72%) was definite by typical manifestation at admission,28 cases(32.18%) were supported by chest X-ray or CT examination because the atypical manifestation,14 severe cases(16.09%) were mistake and omission for the auxiliary examination delayed,8 cases died(9.19%). Conclusion:The main causes of misdiagnosis and miss-diagnosis were atypical clinical manifestation,complicated by COPD,auxiliary examination delayed because of patient's severe condition.The erroneous and delayed treatments may result in high rate of death.
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Chronic obstructive pulmonary disease (COPD) had been considered the only major disease that is continuing to increase in prevalence. There were a few studies about the change of the prevalence of COPD, which showed the prevalence of COPD did not increase. In this review, we report on the trends in the prevalence of COPD in Korea using the data from Korea National Health and Nutrition Examination Survey (KNHANES). The prevalence of COPD in 2015 was 13.4% (male, 21.6%; female, 5.8%). The prevalence of COPD did not change much, which ranged from 13.1% to 14.6% during the period from 2010 to 2015. Among the subjects found to have COPD by spirometry, only 2.8% had been diagnosed as COPD by physicians during the period from 2011 and 2015. In conclusion, the prevalence of COPD did not change significantly during the period from 2010 to 2015. And most COPD patients still had not been diagnosed by physicians and consequently had not been treated appropriately. Keywords: Pulmonary Disease; Chronic Obstructive; Korea; Prevalence; Trends
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Introduction: Chronic obstructive pulmonary disease (COPD) is a systemic disease with multiple extra pulmonary manifestations including impeded skeletal muscle function, leading to decreased muscular strength. Peak expiratory flow rate (PEFR), pulmonary function test monitoring provide a daily objective measure of lung function. A great emphasis has been placed on health related quality of life (airway questionnaire 20) of COPD. Objective: To evaluate the effect of supervised versus home based physiotherapy intervention in stable COPD patients. Methodology: Convenient sampling was used, data were collected from chest medicine department in Shree Krishna Hospital as per the inclusion and exclusion criteria fulfilled with written consent was taken. Patient were divided in to 2 groups, supervised group and home based group (40 in each group). Baseline data were taken from each patients (symptom limited walk test, quadriceps muscle strength, peak expiratory flow rate, pulmonary function test, airway questionnaire 20). Follow up assessment was taken at the end of 4th week. Result: 80 patients were enrolled to receive home based group (n=40) or supervised group (n=40), independent T –Test and paired T-Test and BI –variant analysis done. All parameter significantly improve in supervised group (mean difference [95%CI],p<0.001),FEV1/FVC ratio ( means different [95%CI,p=0.001] than the home based exercise group. Conclusion: Study concluded that supervised physiotherapy group had statistical significant changes seen in pulmonary function, quality of life as well muscle strength and symptom limited walk test than the home base physiotherapy group in stable COPD patients.
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Chronic obstructive pulmonary disease (COPD) is a complex condition, influenced by environmental and/or genetic risk factors. It is important to identify these factors, and develop new therapies for the management of COPD. This review identifies these factors and highlights the role they will play in future treatment options of COPD. (Med J Indones 2001; 10: 178-81)
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Chronic obstructive pulmonary disease (COPD) is associated with frequent hospitalizations, higher mortality, and healthcare costs. Low-income COPD patients have higher rates of emergency department visits and hospitalization due to COPD exacerbation. However, other causes of admissions and their economic burden have not been well-elucidated.We analyzed the Korean National Health and Nutrition Examination Survey (KNHANES) dataset for 2007-2015. The diagnosis and staging of COPD were based on the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines.Among the 97,622 participants in KNHANES for 2007-2015, we selected 33,963 participants (4,430 with and 29,533 without COPD) aged ≥40 years, who underwent spirometry, and provided the admission history for the previous year. Participants with COPD had a higher admission rate than those without COPD (12.8% vs. 10.4%, P<0.001). The admission rate increased as the stage of COPD advanced from GOLD 1 to GOLD 4 for total causes (11.5%, 13.6%, 15.1%, and 25.0%, respectively, P<0.001) and respiratory illnesses (0.5%, 1.3%, 4.6%, and 12.5%, respectively, P<0.001). The proportion of the lowest quartile household income increased in the late stages of COPD (GOLD 1-4; 35.2%, 32.1%, 44.9%, and 70.8%, respectively, P<0.01).The hospitalization rate increased in advanced COPD, while GOLD stages 3 and 4 were associated with deterioration in economic status.
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慢性阻塞性肺疾病(COPD)的发病机制复杂,炎症起中心环节的作用.趋化因子是一类炎症细胞因子,因其具有趋化和激活白细胞的作用,在机体的炎症反应中起着重要的作用.其中趋化因子FKN属于CX3C亚族,有膜结合形式和可溶性游离形式,参与细胞生长调节、血细胞生成、血管生成、细胞间的黏附、免疫炎症等多种生物学功能.现就趋化因子FKN与慢性阻塞性肺病的关系作一简要概述。
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