The Effect of Select Systemic Antihypertensives on the Development of Choroidal Neovascularization in Age-Related Macular Degeneration
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<i>Aim:</i> Evaluation of safety and efficacy of intravitreal ranibizumab in the treatment of choroidal neovascularization (CNV) secondary to causes other than age-related macular degeneration (AMD) or pathological myopia (PM). <i>Methods:</i> Retrospective and multicentric analysis of 21 eyes with CNV. Nine eyes had angioid streaks, 5 inflammatory chorioretinal diseases, 3 central serous chorioretinopathy and 4 idiopathic CNV. Follow-ups lasted ≧3 months. Best-corrected visual acuity (BCVA), ocular coherence tomography (OCT) and fundus examination were assessed monthly. <i>Results:</i> Sixteen eyes (76%) completed 180 days of follow-up. Overall BCVA increased by +9.8 letters with treatment (p = 0.015). Visual acuity improvements ≧15 letters occurred in 43%. A significant reduction in OCT central thickness was observed. No cases of severe visual acuity loss, systemic or ocular side effects were registered. <i>Conclusion:</i> Short-term results of intravitreal ranibizumab for CNV unrelated to AMD or PM are encouraging. This treatment may constitute the only option for some of these patients.
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Age-related macular degeneration is a common blinding eye disease. Because of its pathogenesis of the unknown, there is no precise therapy. At present, more than on the treatment of choroidal neovascularization or dissipated and the suppression start. Photodynamic therapy, laser surgery and treatment for some patients, have a certain effect, the treatment of traditional Chinese medicine has its unique effect, in recent years, anti-vascular endothelial growth factor (anti-VEGF) agents also enable the development of AMD The treatment of a new dawn. This article on age-related macular degeneration treatment for Overview reviewed.
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Combination therapies for choroidal neovascularization secondary to age-related macular degeneration
年龄相关性黄斑变性引起的脉络膜新生血管是中老年人群中心视力丧失的常见原因之一,其治疗已成为眼底病领域研究的热点.目前对脉络膜新生血管的治疗方法有多种,然而现有的任一种单一疗法都难以显著提高视力且复发率较高,不能满足患者需要.近年来,随着对脉络膜新生血管发病机制的深入研究,治疗手段逐渐趋于具不同治疗机制的方法联合应用,以求获得最大疗效并 最大可能减少治疗相关的并发症。
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