Virushepatitis – wann daran denken?
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Abstract Chronic viral hepatitis can remain unrecognized but may nevertheless lead to liver cirrhosis and hepatocellular carcinoma. Thus, patients with elevated liver enzymes as well as risk groups need to be screened and treated for viral hepatitis. These groups include, in particular, migrants from countries with high HBV or HCV prevalence, persons with previous or current intravenous drug use, and homosexual men. For HBV- or HCV-associated diseases, such as panarteriitis nodosa, cryoglobulinemic vasculitis or B-cell lymphoma, antiviral therapy may lead to remission. Prior to high-dose immunosuppressive therapy, especially with regimes containing rituximab, chronic or resolved HBV infection must be ruled out or antiviral prophylaxis may be required to avoid a potentially fatal HBV reactivation.Keywords:
Antiviral Therapy
Viral Hepatitis
Antiviral Therapy
Hepatitis C
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目的 通过检测HBV-DNA定量,对慢性乙型肝炎患者抗病毒的疗效观察.方法 125例慢性乙型肝炎患者,其中HBV-DNA定量1.0×105～9.9×106copies/ml 75例为A组,＞1.0×107copies/ml 50例为B组.两组均用干扰素抗病毒治疗,疗程半年.结果 A组治疗效果优于B组,治疗前HBV-DNA高水平复制者,HBeAg转换率低于HBV-DNA低水平复制.结论 抗病毒的疗效与HBV-DNA在体内复制水平相关;动态检测HBV-DNA定量有利于诊断病情、监测、评价抗病毒的疗效,以及指导用药具有重要意义。
Antiviral Therapy
Clinical Significance
Hepatitis B
Antiviral Treatment
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In recent years, chronic hepatitis C antiviral therapy has achieved some breakthroughs both in standard care optimization and direct-acting antiviral agents. This review describes latest progresses in these two aspects and provides a prospect for new development.
Antiviral Therapy
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In the article basic terms of pharmaco-economics are given; 5 main types of pharmaco-economical analysis illustrated with examples are regarded. The detailed cost-effectiveness analysis of six schemes of chronic hepatitis C antiviral therapy with the use of original data is shown.
Antiviral Therapy
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由中华医学会肝病学分会肝炎学组、中华肝脏病杂志编辑委员会主办的第三届慢性乙型肝炎(CHB)抗病毒治疗难点和热点学术会议,于2011年11月25-27日在桂林召开,庄辉院士、中华医学会肝病学分会候任主任委员魏来教授及副主任委员任红教授与陈成伟教授、中华医学会感染病学分会候任主任委员侯金林教授等国内著名专家及来自全国各地的294位代表参加了会议. 关键词：肝炎;乙型;慢性;肝炎病毒;乙型;抗病毒药;会议纪要
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The article represented the prevalence of chronic hepatitis B and chronic hepatitis C in our country and in the whole world, the modern approaches to the antiviral therapy, the diagnostic algorithms in the assessment of indications and contraindications to the antiviral therapy. There is a modern view on the unsolved problems of the antiviral therapy in such patients.
Antiviral Therapy
Antiviral Treatment
Hepatitis B
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Antiviral Therapy
Antiviral Treatment
Hepatitis B
Chinese population
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The article briefly addresses issues pertaining to the problem of complications encountered in antiviral therapy of patients with chronic hepatitis C. Data on the effectiveness of remaxol as a means of preventing the development of complication in patients with chronic viral hepatitis C in early stages of antiviral treatment.
Antiviral Therapy
Viral Hepatitis
Hepatitis C
Antiviral Treatment
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Antiviral Therapy
Hepatitis C
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