Vaginal Endometriosis: An Enigma for Clinicians
1
Citation
6
Reference
10
Related Paper
Citation Trend
Keywords:
Diathermy
Эндометриоз как эстрогензависимый доброкачественный воспалительный процесс наблюдается приблизительно у 6-10% женщин. Трудности с зачатием имеют от 30 до 40% пациенток с эндометриозом. На сегодня доказана связь между эндометриозом и субфертильностью, раскрываются механизмы негативного влияния на репродуктивную функцию. Однако все еще не до конца решенными и недостаточно изученными остаются вопросы течения беременности у женщин с эндометриозом и влияния эндометриоза на акушерский результат. Данная статья освещает основные вопросы патогенеза и патофизиологии негативного влияния эндометриоза на репродуктивную функцию. Приведены основные механизмы субфертильности при эндометриозе. Особое внимание уделено вопросам взаимосвязи между эндометриозом и осложнениями беременности, патофизиологическим механизмам неблагоприятного влияния эндометриоза на течение беременности и акушерский результат. Endometriosis, as an estrogen-dependent, benign, inflammatory process, is observed in approximately 6-10% of women. Difficulties with conception have from 30 to 40% of patients with endometriosis. To date, the connection between endometriosis and subfertility has been proven, the mechanisms of a negative effect on reproductive function have been revealed. However, the issues of the course of pregnancy in women with endometriosis and the effect of endometriosis on obstetric outcome are still not fully resolved and insufficiently studied. This article highlights the main issues of the pathogenesis and pathophysiology of the negative impact of endometriosis on reproductive function. The main mechanisms of subfertility in endometriosis are presented. Particular attention is paid to the relationship between endometriosis and complications of pregnancy, the pathophysiological mechanisms of the adverse effect of endometriosis on the course of pregnancy and obstetric outcome.
Pathophysiology
Pathogenesis
Cite
Citations (0)
Cite
Citations (46)
Endometriosis is defined as the existence of endometrial tissue outside the uterine cavity, and it includes a chronic, inflammatory reaction associated with female infertility and pelvic pain. Endometriosis occurs in 7 to 10% of women. Although it has been studied for more than 50 years, the pathogenesis and development of endometriosis are still poorly understood. There is no curative therapy for endometriosis, which often recurs after surgical or medical treatment. There is a consensus that the adverse current of menstrual blood plays a crucial role in the development of endometriosis. This places a major limitation on research using rodent models of endometriosis, although these are still widely employed, because rodents do not menstruate and endometriosis does not occur spontaneously in these animals. In fact, menstruation and spontaneous endometriosis only occur in women and some non-human primates, making models that employ non-human primates the best animal models for research into the pathogenesis, pathophysiology, spontaneous onset, and treatment of endometriosis. This review assesses the effectiveness and potential of the non-human primate models of endometriosis. It also describes the current findings and theories on the pathogenesis of endometriosis that have been obtained by research using non-human primates.
Pathogenesis
Uterine cavity
Menstruation
Cite
Citations (31)
Of 132 women with endometriosis, almost one-fifth had peritoneal pockets. Two-thirds of the structures had endometriosis either around the rim or inside. Since one-third of the pockets lacked endometriosis and fibrosis was not present as a possible cause, endometriosis does not seem to have been the likely primary cause. Rather, such peritoneal invaginations and endometriosis may be ontologically related to a separate codevelopmental factor.
Peritoneal fluid
Peritoneal diseases
Cite
Citations (17)
Endometriosis a painful disorder that stripes the uterus both inside and outside. Endometriosis can be diagnosed by the medical practitioners with the help of traditional scanning procedures. Laparoscopic surgery is the authentic method for identifying the advanced stages of endometriosis. The statistical approach is a state-of-art method for identifying the various stages of endometriosis using laparoscopic images. The paper focuses on a well-known statistical method known as chi-square and correlation coefficients are implemented for identifying the symptoms that are correlated with various stages of endometriosis. Chi-square analysis performs the association between symptoms and stages of endometriosis. With these analysis, an algorithm was proposed known as endometriosis prediction factor algorithm (EPF). The EPF algorithm predicts the presence of endometriosis if the derived value is greater than 1. From the chi-square analysis, it is identified that mild endometriosis is influenced 34% by menstrual flow, minimal endometriosis is influenced 40% by dysmenorrhea, where moderate endometriosis is influenced 31% by tenderness and deep infiltrating endometriosis is influenced 22% by adnexal mass.
Cite
Citations (15)
The recognition of endometriosis - the past and the present clinical assessment morphology of the evolution of pelvic endometriosis non-pigmented endometriosis morphology age-related evolution in appearance of endometriosis microscopic endometriosis microscopic endometriosis pelvic peritoneal defects in endometriosis infiltrating endometriosis - infiltrations, retraction or adenomyosis externa? rectovaginal endometriosis ovarian endometriosis ovarian cystoscopy visual appearance of endometriosis of the bowel surgical management of gastro-intestinal endometriosis tubal endometriosis look-alike lesions.
Adenomyosis
Cite
Citations (11)
Cite
Citations (39)
Cite
Citations (18)
Introduction: Endometriosis is a common disease, especially in young women. Inthis article, we reviewed the epidemiology, symptoms, and various options for thetreatment of endometriosis.Material and methods: The work was based on medical articles collected inPubMed, websites and medical books. The research was conducted by looking atkeywords such as: "endometriosis", „endometriosis treatment”, „endometriosis andnew methods"Results: There are many methods of treating endometriosis, ranging fromhormonal therapy to surgical treatment.Conclusions: Endometriosis is difficult disease to treat. We need more researchesand experience to find the perfect way treatment without side effects.
Medical treatment
Cite
Citations (0)
Endometriosis remains one of the most mysterious and controversial diseases in modern gynecology. Contemporary statistical data demonstrate the extreme relevance of actively implementing effective therapeutic approaches into the clinician’s everyday practice. However, a significant challenge associated with endometriosis is the pain syndrome. The question of so-called atypical algological manifestations of endometriosis, which previously seemed unrelated to the pathogenesis of the primary disease, is increasingly raised. In this regard, the aim of this article was to propose a three-level pathogenetic concept capable of linking the primary manifestation of endometriosis (pelvic pain) with other often distant algological patterns, as well as to create an algorithm for managing these patients based on their pathogenetic staging.
Relevance
Clinical Significance
Clinical Practice
Cite
Citations (0)