A cluster of inflammatory rheumatic diseases in a moisture-damaged office.
26
Citation
12
Reference
10
Related Paper
Citation Trend
Abstract:
To describe a cluster of inflammatory rheumatic diseases in an office workplace that suggests the presence of an environmental trigger.There had been an indoor air problem in the workplace since the early 1990s. Large areas of the outer walls of the building were found to be moisture-damaged and contaminated by microbial growth. Case histories of the personnel were studied, and their working areas were related to the areas with highest microbial contamination. The incidence of inflammatory rheumatic diseases was compared with the statistics of the same geographic area.Ten patients with inflammatory rheumatic diseases (3 rheumatoid arthritis, 4 ankylosing spondylitis, 2 Sjögren's syndrome, and one of psoriatic arthritis) entitled to specially reimbursed medication were diagnosed in 1987-2000 (seven cases in 1995-1998). The incidence density ratio computed for the period 1987-2000 was 6.8 (95% confidence interval 3.6-13.0) for all office personnel and 13.2 (6.0-29.0) for those working close to the wall sustaining the worst damage.The accumulation of chronic inflammatory rheumatic diseases in a single workplace suggests that some environmental exposure in this damp office had triggered the diseases.Cite
Cite
Citations (76)
Primary tuberculosis
Primary (astronomy)
Cite
Citations (0)
Evidence of postoperative complications associated with smoking has varied. We conducted this study to clarify the relationships between tobacco smoking and postoperative complications following craniotomy.A retrospective cohort analysis identified 800 patients who underwent cranial surgery with general anesthesia at a medical center with 2700 beds in Seoul, Korea between January and December 2011.Prior smokers (34.8%) and current smokers (35.1%) were hospitalized for at least 11 days longer than never smokers (25.5%) (x2 = 6.74, P=0.036). There were no statistically significant differences in the incidence of postoperative complications among never smokers (5.2%), prior smokers (9.6%), and current smokers (9.6%). The incidences of postoperative complications among prior smokers (9.6%) and current smokers (9.6%) were similar. Comparisons between never smokers (25.5%) and current smokers (34.9%) showed smokers had longer hospital stays and a higher incidence of complications (χ2=6.74, P=0.012). The incidence of major complications (χ2=5.27, P=0.024) and overall complications (χ2=4.84, P=0.033) were also significantly higher among smokers than never smokers. The impact of smoking status on postoperative complications was not identified.We found significant associations between smoking status and postoperative complications. The incidence of major complications was twice as high among smokers as among never smokers. Therefore, it is recommended to continuously monitor current smokers to prevent postoperative complications after craniotomy.
Cite
Citations (0)
Cite
Citations (32)
Rheumatic disease
Cite
Citations (3)
Caesarian section
Cite
Citations (0)
Perforation
Rheumatic disease
Gastrointestinal perforation
Safety profile
Cite
Citations (83)
Univariate analysis
Cite
Citations (0)
Abstract Introduction Rheumatic diseases (RDs) are associated with different cancers; however, it is unclear whether particular cancers are more prevalent in certain RDs. In the present study, we examined the relative incidence of several cancers in a single homogeneous cohort of patients with different RDs. Methods Patients ( N = 3,586) diagnosed with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc), dermatomyositis (DM) or polymyositis were included. Cancer diagnosis was based on histopathology. The 2008 Korean National Cancer Registry served as the reference for calculating standardized incidence ratios (SIRs). Results During the follow-up period of 31,064 person-years, 187 patients developed cancer. RA and SLE patients showed an increased risk of non-Hodgkin’s lymphoma (SIR for RA patients = 3.387, 95% confidence interval (CI) = 1.462 to 6.673; SIR for SLE patients = 7.408, 95% CI = 2.405 to 17.287). SLE patients also had a higher risk of cervical cancer (SIR = 4.282, 95% CI = 1.722 to 8.824). SSc patients showed a higher risk of lung cancer (SIR = 4.917, 95% CI = 1.977 to 10.131). Endometrial cancer was increased only in patients with DM (SIR = 30.529, 95% CI = 3.697 to 110.283). RA patients had a lower risk for gastric cancer (SIR = 0.663, 95% CI = 0.327 to 0.998). The mean time between the RD and cancer diagnoses ranged from 0.1 to 16.6 years, with the shortest time observed in patients with DM (2.0 ± 2.1 years). Conclusions Different RDs are associated with particular cancers. Thus, cancer surveillance tailored to specific RDs might be beneficial.
Cite
Citations (51)
Journal Article Incidence, aetiology, diagnosis, and prognosis of closed abdominal injuries, A study of 265 consecutive cases Get access David H Wilson David H Wilson Research Assistant The Casualty Department of the General Infirmary at Leeds Search for other works by this author on: Oxford Academic Google Scholar British Journal of Surgery, Volume 50, Issue 222, January 1963, Pages 381–389, https://doi.org/10.1002/bjs.18005022206 Published: 06 December 2005
Etiology
Cite
Citations (22)