The effects of cervical carcinoma with metastasis of pelvic lymph node
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Objective To study the clinical pathological characteristics of patients with cervix cancer, as well as the relationship between the pelvic lymph node metastasis, find out the risk factors of lymph node metastasis.Methods Through a retrospective analysis of our hospital from January 2010 to January 2010, 156 cases of cervical cancer patients with the clinical pathological data, the relationship between the analysis with the pelvic lymph node metastasis.Results 156 patients occurred in 41 cases of pelvic lymph node metastasis, the incidence was 26.28%.Conclusion Cervical cancer patients with pathological grade, clinical stage and tumor diameter, infiltrating depth are affect the risk factors of pelvic lymph node metastasis, during the radical surgery for cervical cancer patients should pay attention to the impact of these risk factors.
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Uterine cancer
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OBJECTIVE:To investigate the relative factors of cervical carcinoma with metastasis of pelvic lymph node.METHODS:Clinical data were analysed retrospectively in 305 patients with stage ⅠA-ⅡB cervical carcinoma who underwent radical hysterectomy for cervical carcinoma.RESULTS:The metastasic rate of pelvic lympynode in stageⅠA was 0,in stage ⅠB 9 8%,in stage ⅡA 18 52%,in stage ⅡB 57 14%.The metastasic rate of pelvic lympynode in cervical squamous carcinoma was 8 2%,in cervical adenocarcinoma 42 27%.The metastasic rate of pelvic lympynode in cervical carcinoma well differentiated was 0,in moderate differentiated 11 16%,in poorly differentiated 40 62%.The metastasic rate of pelvic lymph node in stromal invasive depth 1/2 was 1 23%,in≥1/2 21 88%.The metastasic rate of pelvic lymph node in erosive type was 17 02%,in exophytic type 13 95%,in endophytic type 18 52%,in ulcerative type 41 67%.The metastasic rate of pelvic lymph node in cervical carcinoma≥4 cm was 20 0%,in4 cm 12 14%.The metastasic rate of pelvic lymph node in preoperative chemotherapy was 7 40%,in no chemotherapy 19 56%,in preoperative radiotherapy 4 76%,in no radiotherapy 19 56%.CONCLUSIONS:The influence of metastasis pelvic lymph node of cervical carcinoma may be directly related to the clinical stage,cell differentiation, pathological,invasive depth of cervical stroma,modality of growth,preoperative chemotherapy or radiotherapy.The size of tumor may be not apparently related to metastasis pelvic lymphnode.
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Objective:To explore the features of pelvic lymph node metastasis,the related prognostic factors and the influence to outcome in stage Ⅰ,Ⅱcervical cancer patients.Methods:We retrospectively analyzed 32 cervical cancer patients with lymph node metastasis and 32 cases without lymph node metastasis,who had undertaken extensive hysterectomy and radical pelvic lymphoadenectomy.Results:The lymph node metastasis rate was 23.35%,and the most common metastasis of cervical carcinoma occurred at the obturator node(59.37%).Pelvic lymph node metastasis was associated with deep cervical stromal invasion,which was not correlated with age,histological classification,the grade of differentiation,parametrial involvement,and lymphovascular invasion.The relevant prognostic factor for cervical carcinoma was number of lymph node metastasis,and was not the depth of cervical stromal invasion,histological classification,the grade of differentiation and lymphovascular invasion.Conclusion:The stromal invasion ≥l/2 is a risk factor of pelric lymph node metastasis in cervical cancer.The prognosis of patients with ≥3 positive pelvic lymph node are quite poor,which is helpful for clinical therapy.
Lymphovascular invasion
Parametrial
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Objective:To study the influential factors of cervical carcinoma with metastasis of pelvic lymph node. Methods: Clinical data were analized retrospectively in 381 patients with stage I~II cervical carcinoma. Results: The metastatic rate of pelvic lymphnode in stage IA was 2%,in stage IB 11.9%, in stage IIA 16%,in stage IIB 18.5%.The metastasis rate of pelvic lymph node related with pathological type,size of tumor , cell differentiation and preoperative chemotherapy(P0.05).The clinical stage and preoperative radiotherapy may be not apparently related to metastasis pelvic lymphnode(P0.05). Conclusion: Metastasis of pelvic node of cervical carcinoma may be related with pathological type, size of tumor and cell differentiation. risk effects of cervical carcinoma befor our operation.
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Objective To investigate the effects of cervical carcinoma with metastasis of pelvic lympy node .Methers Clinical meterials were analized retrospectively in 116 patients with stage I～II cervical carcinoma and metastasis and recurrent carcinoma.Results The metastics rate pelvic lympynode in stage was 6.67%, in stage II was 34.61%, and recurrent and metastasis cancer was 35.29%.The metastasis rate of pelvic lymph node related with clinical stage, pathological type, size of tumor and cell differentiation.Colusion The inflence of metastasis pelvic node of cervical carcinoma may be related with clinical stage, pathological, size of tumor and cell differentiation. We should consider risk effects of cervical cancer in our magement.
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e18005 Background: Evaluation the distribution of nodal metastases in the stage IB1 cervical cancer and the risk factors associated with pelvic lymph node metastasis (LNM) at each anatomic location. Methods: 728 patients with stage IB1 cervical cancer who underwent radical hysterectomies and systemic pelvic lymphadenectomies from January 2008 to December 2017 were retrospectively studied. All removed pelvic lymph nodes were pathologically examined, and the risk factors for LNM at the obturator, internal iliac, external iliac, and common iliac regions were evaluated by univariate and multivariate logistic regression analyses. Results: 20,134 lymph nodes were analysed with the average number of 27.80 (± SD 9.43) lymph nodes per patient. Nodal metastases were present in 266 (14.6%) patients. The obturator was the most common site for nodal metastasis (42.5%) followed by the internal iliac nodes (20.3%) and the external iliac nodes (19.9%), while the common iliac (9.8%) and parametrial (7.5%) nodes were the least likely to be involved. Tumor size more than 2 cm, histologically proven lymphovascular space involvement (LVSI) and parametrial invasion correlated independently significantly with the higher risk of the lymphatic metastasis. Obesity (BMI≥25) was independently significantly negatively correlated with the risk of lymphatic metastases. All the positive common iliac nodes were found in patients with tumors greater than 2 cm. The multivariate analysis showed that tumor size greater than 3 cm was associated with a 16.6-fold increase in the risk for common iliac LNM. Interestingly, tumor size was not an independent risk factor for pelvic LNM in the lower regions, i.e., the obturator, internal iliac and external iliac areas, where LVSI was the most significant predictor for LNM. In addition, parametrial invasion was related to external and internal iliac LNM; deep stromal invasion and age less than 50 years were associated with obturator LNM. Conclusions: The incidence of lymph node metastasis in patients with stage IB1 cervical cancer is low but prognostically relevant. The data offer the opportunity for tailored individual treatment in selected patients with small tumors and obesity.
Parametrial
Lymphovascular invasion
Univariate analysis
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