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    [50] The efficacy and safety of low-intensity shockwave therapy in erectile dysfunction
    Arab Journal of Urology (2018)
    Riyad Al MousaAbdulrahman AlmuhrijMohammed AlmujhimHassan AlsayeghAbdulmohsin AlfadaghHamed AlaliAdel Aldayel
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    Abstract:
    ObjectiveTo assess the effectiveness and safety of low-intensity extracorporeal shockwave therapy (Li-ESWT) on patients with erectile dysfunction (ED).
    Keywords:
    Extracorporeal shockwave therapy
    Intensity
    Extracorporeal
    Topics:
    Sexual function and dysfunction studies
    Urinary Bladder and Prostate Research
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    Predictors of Successful Erectile Function Using Intracavernosal Injection in Post-Prostatectomy Men with Erectile Dysfunction
    Yotam VeredgornZiv SavinRon MaromHaim HerzbergAmihay Nevo
    Abstract Intracavernosal injections (ICI) are commonly used to treat erectile dysfunction in men following radical prostatectomy (RP). Predictors of treatment success are still unclear. Our objective is to explore the relationship between various clinical and pathological parameters and the achievement of satisfactory erections with ICI following RP. A prospective study of men following RP with bilateral neurovascular bundle preservation who experienced erectile dysfunction refractory to treatment with phosphodiesterase type 5 inhibitors (PDE5I) at a minimum of 6 months after surgery. Three escalating dosages of TRIMIX were used consecutively (5mg Papaverine, 0.5 mg Phentolamine, 10mcg Alprostadil; 10mg Papaverine, 1 mg Phentolamine, 20 mcg Alprostadil; 17mg Papaverine, 1mg Phentolamine, and 30mcg Alprostadil). Erection Hardness Scale (EHS) and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) were used for functional assessments. Thirty four patients were stratified by their EHS scores and Trimix dosages: low dose full responders (N=12), intermediate dose full responders (N=10), high dose partial responders (N=7), high dose failures (N=5). Twenty nine (85%) of the patients reported on satisfactory erectile function with ICI. The ICIQ-SF scores were the only parameter that correlated significantly with successful erectile response with mean scores of 2.58, 4.7, 9.57, and 14.8 for the respective groups above (p=0.001). Multivariate analysis identified ICIQ-SF as the only independent predictor of success (OR 0.74, p=0.002). ICI is an efficient therapy for achieving satisfactory erections following RP in PDE5I-resistant men. Sustainable urinary incontinence is a strong predictor of poor response to therapy.
    Citations (0)
    397 Low Intensity Extracorporeal Shockwave Therapy can Improve Erectile Function in Patients Who Responded Poorly to PDE5 Inhibitors
    The Journal of Sexual Medicine (2016)
    C.C. LiuChia‐Chun TsaiY.C. LeeC.J. WangJiun‐Hung Geng
    Extracorporeal shockwave therapy
    Intensity
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    Low intensity extracorporeal shockwave therapy can improve erectile function in patients who responded poorly to PDE5 inhibitors
    Urological Science (2016)
    Chia‐Chu LiuChia‐Chun TsaiJiun‐Hung GengChii‐Jye Wang
    Extracorporeal shockwave therapy
    Intensity
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    Is Li-ESWT effective in diabetic patients with severe erectile dysfunction?
    Asian Journal of Andrology (2022)
    Müslüm ErgünOsman Akyüz
    Noninvasive low-intensity extracorporeal shockwave treatment (Li-ESWT) has been widely used to treat erection disorders. There is no clear information regarding either the selection of patients for the treatment or the treatment protocol. In this study, we aimed to investigate the efficacy of extracorporeal shockwave therapy in diabetic patients with severe erectile dysfunction (International Index of Erectile Function-5 [IIEF-5] scores of 5 to 7). Sixty-three diabetes mellitus patients with erectile dysfunction having IIEF-5 scores of 5 to 7 and not showing a recovery of potency despite phosphodiesterase type 5 inhibitor therapy for the past 6 months were included in the study. The patients were evaluated based on their IIEF-5 scores and Erection Hardness Scale scores. The IIEF-5 score (mean ± standard deviation [s.d.]) increased from 5.29 ± 1.67 to 5.56 ± 1.85, with a difference of 0.27 ± 0.18 (P > 0.05). The Erection Hardness Scale scores (mean ± s.d.), on the other hand, increased from 1.46 ± 0.50 to 1.48 ± 0.50, with a difference of 0.02 ± 0 (P > 0.05). In conclusion, the response to phosphodiesterase type 5 inhibitors did not change after extracorporeal shockwave treatment in diabetes mellitus patients with severe erectile dysfunction (IIEF-5 scores of 5 to 7).
    Extracorporeal shockwave therapy
    Extracorporeal
    Citations (7)
    The effect of antihypertensive treatment on erectile function
    American Journal of Hypertension (2005)
    Michael DoumasA. TsakirisΣτέλλα ΔούμαAthina HountaAnastasios Papadopoulos
    The aim of our study was to investigate the effect of antihypertensive treatment on erectile function in patients with essential hypertension. From our hypertension outpatient clinic, 358 consecutive young and middle-aged men (31–65 years old, 49.1±5.2 years) with essential hypertension filled a questionnaire regarding erectile function (International Index for Erectile Function). Antihypertensive therapy significantly affected the erectile function of our patients, with patients on combination therapy exhibiting the higher prevalence of erectile dysfunction. Older antihypertensive drugs exhibit worse profile on erectile function than newer drugs, suggesting that this may be another parameter for the proper choice of antihypertensive drug.
    Antihypertensive drug
    Pharmacotherapy
    Essential hypertension
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    Can Low-Intensity Extracorporeal Shockwave Therapy Improve Erectile Function? A 6-Month Follow-up Pilot Study in Patients with Organic Erectile Dysfunction
    Yearbook of Urology (2011)
    A.W. Shindel
    Extracorporeal shockwave therapy
    Extracorporeal
    Citations (25)
    Shockwave Therapy for Erectile Dysfunction
    Deleted Journal (2023)
    Low-intensity extracorporeal shockwave therapy similar to that used to fragment kidney stones or gallstones is a new option for treatment of erectile dysfunction that is now being advertised extensively in the US. It has not been approved by the FDA for treatment of erectile dysfunction.
    Extracorporeal shockwave therapy
    Extracorporeal
    Citations (0)
    The herbal composition Green Love® improves erectile function in patients with erectile dysfunction: A pilot study to evaluate effectiveness and safety
    European Urology Supplements (2017)
    Ralf HerwigJoachim GreilbergerMichaela GreilbergerPeter Weibl
    Citations (1)
    Age-related erectile function differences among erectile dysfunction patients
    The Chinese Journal of Human Sexuality (2014)
    Ka Zhang
    Objectives: To investigate the age-related differences of erectile function and erectile hardness in erectile dysfunction( ED) patients. Method: The data were retrieved in a baseline database on an ED management study which was performed in 46 urological clinics in China. The patients were stratified on the basis of every 10 years( yrs) old. International Index of Erectile Function( IIEF-EF) and Erection Hardness Score were adopted as the scale to evaluate erectile functions and the Erection Hardness Score( EHS). Statistical analysis were then done to make comparisons among different age groups. Results: The study included 4241 ED patients with an age range from 20 to 84 yrs( average 42. 3 ± 12. 3 yrs); 55. 6% patients were between 31 to 50 yrs old. For patients over 30 yrs old,with the increase of age,both scores of IIEF-EF and EHS tended to decrease. Decrease of erectile function and erectile hardness scores were statistically significant between the patients aged over and below 50 yrs, and the conditions were even worse in the patients over 60 yrs. Conclusion: This study suggested that for men below 50 yrs old,prevention and treatment of ED were essential; while for those over 50 yrs old,the treatment of ED and the prevention of its comorbidities were highly recommended.
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