Usage of ultrasonography in gallbladder lesions. Analysis of 85 cases: a single centre study
1
Citation
0
Reference
10
Related Paper
Citation Trend
Keywords:
Histopathology
Gallbladder Cancer
Abdominal ultrasonography
Common hepatic duct
Background: Gallbladder polyps are now increasingly detected by ultrasonography. There are many studies reporting theprevalence of gallbladder polyp, however there is no report in Jeju island. The purpose of this study is to research prevalenceand clinical characteristics of gallbladder polyps in adults living in Jeju island.Methods: We have evaluated 3,471 populations who underwent abdominal ultrasonography for health screening examinationat Jeju National University Hospital in Jeju, Korea from January 2011 to June 2012.Results: Prevalence of gallbladder polyp in Jeju island is 10.1%. Prevalence in males is 11.6% and that in females is8.2%(P<0.001). The size of gallbladder polyps mostly are less than 5mm in diameter. 216 subjects (61.5%) have single polypand 135(38.5%) subjects have multiple gallbladder polyps which means 2 or more polyps.Conclusions: The prevalence of gallbladder polyp in Jeju island has found to be higher than the pre-existing reports and theprevalence is higher in males than females. Most polyps are small and single.
Abdominal ultrasonography
Cite
Citations (0)
Abdominal ultrasonography
Cite
Citations (1)
Ciliated foregut cyst of gallbladder is a very rare benign cystic lesion. A 39-year-old woman was referred to our hospital after abdominal ultrasonography revealed a cystic lesion of gallbladder. On abdominal ultrasonography and computed tomography, a unilocular cystic lesion was found at right upper quadrant with attachment to the gallbladder neck. The gallbladder with cystic lesion was resected through laparoscopic cholecystectomy. The cystic lesion revealed a unilocular cyst with ciliated cuboidal or columnar epithelium and abundant goblet cells. Pathologic examination is essential to distinguish from other cystic lesions of the gallbladder and avoid unnecessary additional treatment. In the current case report, we presented the clinico-pathologic findings of the ciliated foregut cyst of the gallbladder and review of literature.
Foregut
Abdominal ultrasonography
Quadrant (abdomen)
Cite
Citations (0)
Adenomyomatosis (ADM) of the gallbladder is a condition characterized by the proliferation of Rokitansky-Aschoff sinus (RAS), in which the epithelium of the gallbladder extends into the muscular layer, causing a thickening of the gallbladder wall. Although ADM is generally considered not to be a precancerous lesion of gallbladder cancer, there are some reports of cases of gallbladder cancer from ADM. Therefore, the relationship between ADM and gallbladder cancer remains controversial. We herein report a case of early-stage gallbladder cancer, BilIN3 (high grade), arising from ADM that was positive for ALDH1A1, an important marker of stem cells and cancer stem cells.
Adenomyomatosis
Gallbladder Cancer
Cite
Citations (0)
Objective To investigate the clinical value of contrast-enhanced ultrasound(CEUS) in the diagnosis of gallbladder cancer.Methods Twenty patients with gallbladder cancer and thirty-seven patients with benign gallbladder disease underwent conventional ultrasound and real-time CEUS.The enhancement patterns including types of time-intensity curve,centripetal fill-in,homogeneity and intensity of enhancement were analyzed.Results The focus and gallbladder wall in gallbladder cancers were enhanced at the same time,hepatic artery phase was mainly highly enhanced,hepatic portal vein phase was mairdy lowly enhanced.The percentages of those lesions that exhibited hyper-enhancement or iso-enhancement in the early phase and turned to hypo-enhancement within 35 s after contrast agent administration were 95.0%(19 /20) in gallbladder cancers and 16.2%(6 /37) in benign lesions(P = 0.000).Inhomogeneous enhancement was found 80.0%(16 /20) in gallbladder cancers and 23.3%(7 /30) in benign lesions (P =0.000).Destruction of the integrality of gallbladder wall was found 85.0%(17/20) in gallbladder cancers and none(0.0%,0 /37) in benign lesions(P = 0.000).The diagnose accordance rate、sensitivity and specificity of benign and malignant gallbladder diseases by CEUS was were 92.98% 、95.00% and91.83%,respectively.Conclusion CEUS can improve the diagnosis rates of gallbladder cancer and the ability of differentiating diagnosis between benign and malignant gallbladder diseases compared with conventional ultrasound.
Contrast-enhanced ultrasound
Gallbladder Cancer
Gallbladder disease
Adenomyomatosis
Cite
Citations (0)
Objective To evaluate endoscopic ultrasonography (EUS) in the diagnosis of gallbladder carcinoma. Methods To compare the results of EUS and abdominal ultrasonography, CT/MRI in 18 cases of gallbladder carcinoma. Results Among these cases, 17, 15 and 5 cases of gallbladder carcinoma were diagnosed by EUS, CT/MRI and abdominal ultrasonography respectively. The sensitivity and accuracy of EUS was higher then those of abdominal ultrasonography, but similar to CT/MRI. The diagnosis of 13 operated patients were compared with the histological examination, the diagnostic accuracy were 92％ , 76.9％ (P 0.05) and 41.6％ (P 0.01) in EUS, CT/MRI and abdominal ultrasonography examinations respectively. Conclusion EUS had significant value in the diagnosis of gallbladder carcinoma.
Abdominal ultrasonography
Endoscopic ultrasonography
Cite
Citations (0)
Gallbladder cancer (GBC) has a high incidence in certain geographical regions. Morphologically, GBC presents as a mass replacing the gallbladder, a polypoidal lesion, or wall thickening. The incidence of preoperative diagnosis of wall thickening type of GBC is less well studied. The patterns of mural involvement and extramural spread are not well described in the literature. Additionally, wall thickening in the gallbladder does not always indicate malignancy and can be secondary to inflammatory or benign gallbladder diseases and extracholecystic causes and systemic pathologies. Objective reporting of gallbladder wall thickening will help us appreciate GBC's early features. In this review, we illustrate the imaging patterns of wall thickening type of GBC.
Gallbladder Cancer
Cite
Citations (10)
Lumen (anatomy)
Adenomyomatosis
Abdominal ultrasonography
Cite
Citations (22)
Ciliated foregut cyst of gallbladder is a very rare benign cystic lesion. A 39-year-old woman was referred to our hospital after abdominal ultrasonography revealed a cystic lesion of gallbladder. On abdominal ultrasonography and computed tomography, a unilocular cystic lesion was found at right upper quadrant with attachment to the gallbladder neck. The gallbladder with cystic lesion was resected through laparoscopic cholecystectomy. The cystic lesion revealed a unilocular cyst with ciliated cuboidal or columnar epithelium and abundant goblet cells. Pathologic examination is essential to distinguish from other cystic lesions of the gallbladder and avoid unnecessary additional treatment. In the current case report, we presented the clinico-pathologic findings of the ciliated foregut cyst of the gallbladder and review of literature.
Foregut
Abdominal ultrasonography
Quadrant (abdomen)
Choledochal Cysts
Cite
Citations (6)
The similarity of gallbladder cancer and benign gallbladder lesions brings challenges to diagnosing gallbladder cancer (GBC). This study investigated whether a convolutional neural network (CNN) could adequately differentiate GBC from benign gallbladder diseases, and whether information from adjacent liver parenchyma could improve its performance.Consecutive patients referred to our hospital with suspicious gallbladder lesions with histopathological diagnosis confirmation and available contrast-enhanced portal venous phase CT scans were retrospectively selected. A CT-based CNN was trained once on gallbladder only and once on gallbladder including a 2 cm adjacent liver parenchyma. The best-performing classifier was combined with the diagnostic results based on radiological visual analysis.A total of 127 patients were included in the study: 83 patients with benign gallbladder lesions and 44 with gallbladder cancer. The CNN trained on the gallbladder including adjacent liver parenchyma achieved the best performance with an AUC of 0.81 (95% CI 0.71-0.92), being >10% better than the CNN trained on only the gallbladder (p = 0.09). Combining the CNN with radiological visual interpretation did not improve the differentiation between GBC and benign gallbladder diseases.The CT-based CNN shows promising ability to differentiate gallbladder cancer from benign gallbladder lesions. In addition, the liver parenchyma adjacent to the gallbladder seems to provide additional information, thereby improving the CNN's performance for gallbladder lesion characterization. However, these findings should be confirmed in larger multicenter studies.
Gallbladder Cancer
Cite
Citations (6)