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    benign lesions, retrorectal cystic hamartomas should be routinely resected in order to confirm diagnosis and avoid malignant transfor- mation or local complications.
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    Abstract:
    Skin involvement in leukemias may be the consequence of spe-cific infiltration (leukemia cutis), such condition being very rare inacute leukemias; on the contrary, the more frequent secondarynonspecificlesionsdonotcontainleukemiccellsandincludepurpura,maculopapules, erythroderma, herpes zoster or simplex lesions, bul-lae,furuncles,exfoliation,eczema,andEN.Inourpatient,ENwasevidentatdiagnosisofAML,andalthougha causal relationship between the two conditions could not be ascer-tained,thecompleteresolutionofENafterthefirstcourseofchemo-therapystronglysuggestsitscorrelationtoleukemia.
    Keywords:
    Erythroderma
    Cutis
    Leukemia cutis
    Epidermoid cysts are common benign disorders of the skin,which occur frequently in the scalp and in the skin of the neck and back . When they develop in the breast parenchyma they are an uncommon benign con- dition, yet have the potential for malignancy.The diagnosis of this condition may not be straightforward with imaging alone. An epidermoid cyst presenting as an enlarging lump in the breast may mimic a benign breast lesion such as fibroadenoma or malignant lesion with benign imaging features. Excision is recommended for definite histopathological diagnosis and to prevent potential risk of malignant transformation.
    Epidermoid cyst
    Cutaneous cystic lesions have broad differentials ranging from common benign entity to rare malignant lesions. Clinical evaluation of the lesion is the key to differentiation, as some rare malignant entities may simulate benign lesions. A high index of suspicion should be maintained for any aggressive behavior, which may require more thorough evaluation, including histopathology and radiographic imaging studies. We report a rare case of cystic poorly differentiated squamous cell carcinoma (CPDSCC) of the scalp.We report a case of a 37-year-old Filipino expatriate male who presented with a scalp swelling which had been gradually increasing in size for four months and was operated upon with a working diagnosis of sebaceous cyst. On post-op excisional biopsy, it turned out to be poorly differentiated cystic squamous cell carcinoma of the scalp. On further workup, no metastasis or other primary was found. Complete re-excision of the lesion with no evidence of residual tumor was achieved. Long-term follow-up was lost, as the patient left for his native country.Though cystic cutaneous lesions are very commonly encountered in clinical practice, high suspicion for malignancy should be maintained if the lesion shows any aggressive behavior. Prompt investigation should be done before surgery to determine the nature of the disease and the most effective management for the patient. Poorly differentiated cystic squamous cell carcinoma should also be considered in the differential diagnosis of cystic cutaneous lesions show aggressive behavior.
    Wide local excision
    Rare disease
    The most common benign liver tumors are hamartomas and hemangiomas, which both originate in mesenchymal tissue (1, 2). Infan® le myo® bromatosis (IM) is a rare mesenchymal tumor involving musculoske le tal subcutaneous and visceral ® brous tissue (2, 3). It is conside red to be the most common ® brous tumor of infancy (2) and represents a clinically and histologically distinct form of infantile ® bromatosis (4, 5). The term IM was coined by Chung and Enzinge r in 1981 (4). Based on the anatomic distribution of the lesions, two forms are described: (1) solitary lesions involving mainly the skin, muscle, or subcutaneous tissue; and (2) multicentric lesions con® ned to soft tissue s and bone (2, 4). Although both forms are most frequently apparent at birth (2, 3), solitary le sions may also be diagnose d late r in life (2). The prognosis is good when the lesions, e ithe r solitary or multicentric, are con® ned to skin, muscle, and bone. However, when the lesions are multicentric with visceral involvement, death commonly results from cardiopulmonary and gastrointe stinal complications . In addition, all lesions, regardle ss of their form, may recur (2, 4, 5). Isolated hepatic IM is exceptionally rare , and to our knowledge this is only the second reported case. Microscopical ly, it consists of ® broblastic and smooth muscle cell prolife ration and hence is classi® ed as a primary benign hepatic mesenchymal hamartoma (2± 7). Most lesions regress spontane ously (2). However, the anatomic location and the local invasive ness of this tumor remain the most important determinants of its clinical course (2, 4, 5). For this reason, we thought it desirable to report a case of an isolate d hepatic IM where a live r transplant constitute d an important therapeutic approach with excellent longterm prognosis.
    Hamartoma
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    Iwatsuki, S., Todo, S. and Starzl, T.E. (1990) Excisional therapyfor benign hepatic lesions. Surgery Gynecology & Obstetrics; 171 240-246. With the recent advances in imaging techniques, increased numbers of hepatic lesions are found today, and surgeons are asked frequently for the best course of management. Benign hepatic tumors sometimes cause life-threatening complications and more often trigger disabling or annoying symptoms in otherwise healthy individuals. Although various imaging techniques are quite accurate in identifying cysts and hemangiomas, other benign hepatic lesions, such as adenomas, focal nodular hyperplasia and other benign solid tumors, cannot be differentiated from malignant lesions with a high degree of confidence.
    Focal nodular hyperplasia
    Benign tumor
    Citations (0)
    Benign skin tumors are commonly seen by family physicians. The ability to properly diagnose and treat common benign tumors and to distinguish them from malignant lesions is a vital skill for all family physicians. Any lesions for which the diagnosis is uncertain, based on the history and gross examination, should be biopsied for histopathologic examination to rule out malignancy. Lipomas are technically subcutaneous soft tissue tumors, not skin tumors, and controversy exists about whether keratoacanthomas have malignant potential; however, both are discussed in this article because they are common tumors evaluated by family physicians. Diagnosis usually is based on the appearance of the lesion and the patient's clinical history, although biopsy is sometimes required. Treatment includes excision, cryotherapy, curettage with or without electrodesiccation, and pharmacotherapy, and is based on the type of tumor and its location. Generally, excision is the treatment of choice for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, and epidermoid cysts. Cherry angiomas and sebaceous hyperplasia are often treated with laser therapy and electrodesiccation. Common treatments for acrochordons and seborrheic keratoses are cryotherapy and shave excision. Referral is indicated if the family physician is not confident with the diagnostic evaluation or treatment of a lesion, or if a biopsy reveals melanoma.
    Cryotherapy
    Curettage
    Cryosurgery
    Atypia
    Citations (85)
    Papillary lesions of the breast include various benign, atypical, and malignant lesions. These lesions clinically, radiologically and histologically are not only may interfered as benign breast lesions but also can be confused as malignant lesions. However, cause the fact that the treatment methods vary according to the precise diagnosis, definitive diagnosis gain importance. In this article; the clinical, radiological, pathological features, and treatment modalities of papillary type breast lesions was presented with a case report.
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