Avaliação da função renal de cães submetidos a administração de Flunixin Meglumine durante a anestesia geral
Renato Silvano PulzJussara Zani MaiaBianca do P. L. PetrucciFabiana SchiochetRodrigo Fiori S. SilveiraQueti Ferrari
0
Citation
0
Reference
0
Related Paper
Abstract:
The administration of non steroid antiinflammatory (AINEs) to guarantee the post – operation analgesia is a common practice in veterinary medicine. These agents constitute a group of drugs of wide application in analgesia of small sized animals. The AINEs reduce the inflammation by blocking the enzynes which are responsible for the transformation of arachnoidal acid into a series of substances that cause the inflammatory process, such as the prostaglandins. Flunixin Meglumine is one of the most used analgesics to control the post operation and acute pain. The main focus of this study was to check the effects on to the renal function of dogs that undergo the administration of Flunixin Meglumine during the general anaesthesia. Twenty four adult dogs without a defined race and weighing between 5 and 20 Kg were evaluated. The animals were kept under inhalant general anaesthesia and received an administration of 1,1 mg/ kg of Flunixin Meglumine via intravenous during the trans-anaesthetics. The medium arterial pressure and cardiac frequency were measured the moment of administration and blood level of urea and creatinine were evaluated 24 hours later. The media valves obtained from the medium arterial pressure and the cardiac frequency ranged from 118,9 ±18,1 and 88,5±12,4 respectively. The media valves obtained after the treatment of urea was 15,52 ± 4,9 and creatinine was 0,7 ± 0,13. With the above data we can conclude that the administration of these drugs performed in dogs under general anaesthesia and with medium arterial pressure kept normal has not produced any alteration to the renal function.Keywords:
Meglumine
Cite