Beyond Positive Margins and Extracapsular Extension: Evaluating the Impact of Postoperative Chemoradiation Therapy in Locally Advanced Head and Neck Cancer
Daniel M. TrifilettiAlexander LinJohn N. LukensWilliam M. MendenhallNandita MitraPaul W. ReadSamuel Swisher‐McClure
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Adjuvant Therapy
Introduction. Squamous cell carcinoma (SCC) of the larynx accounts for a significant percentage of all head and neck cancers. Aim. In this paper we determine the differences in magnetic resonance relaxation time (MRI) of water in cancerous and healthy larynx tissues. Material and methods. This study is aimed on T2 MRI modalities for monitoring morphology of larynx tissue. Results. Our results showed that T2 MRI relaxation time measured in larynx tissue can be used to assess early cancer condition of larynx tissues. The changes of T2 MRI correspond to tumor growth within normal tissue. Conclusion. The study showed potential of MRI for the non-invasive monitoring of larynx condition.
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CO2 laser surgery is becoming a part of larynx surgery. The authors inform about their experience in benign larynx tumours treatment. They present analysis of concrete therapeutic procedures in individual larynx affections. They conclude that laser surgery is an advantegous method for benign larynx tumours treatment.
Laryngeal Diseases
Laser Treatment
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Other SectionsAbstractINTRODUCTIONHISTORY OF LASER TREATMENT FOR LARYNX CANCERTYPES OF LASER TECHNOLOGIES USED IN LARYNX CANCER TREATMENTBENEFITS AND RISKS OF LASER TREATMENT FOR LARYNX CANCERLIMITATION OF LASER TREATMENT FOR LARYNX CANCERRADIATION AND CHEMOTHERAPY AFTER LASER TREATMENT FOR LARYNX CANCERCOMPLICATION OF LASER TREATMENT FOR LARYNX CANCERLASER TREATMENT FOR LARYNX CANCER: FUTURECONCLUSIONACKNOWLEDGMENTSAUTHOR CONTRIBUTIONSCONFLICT OF INTERESTFUNDINGDATA AVAILABILITYSUPPLEMENTARY MATERIALSReferences
Laser Treatment
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Larynx is a term that refers to the tubular organ that lies between the pharynx and the trachea. The larynx, which appears in most vertebrates, is made up of nine cartilages and is a key piece in the phonation apparatus.
In humans, the larynx is located in the anterior part of the neck and borders it with the upper part of the trachea. Constituted as the organ of phonation, the larynx responds to the needs of voice and phonation by containing the upper and lower vocal cords.
The invasion of a virus or bacteria, the swelling of viruses and cancer are some of the diseases that affect the larynx.
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Benign tumors of the larynx are of interest and importance to the laryngologist, not only because of the symptoms which they produce by interference with the normal functions of the vocal mechanism or by obstruction of the respiratory tract but because of the necessity of distinguishing them from malignant laryngeal lesions. Tumors of a bengin nature do not occur frequently in the larynx. During the past thirty years 722 patients with benign laryngeal growths have been examined at the Mayo Clinic. It is interesting to find that these tumors, apparently, are encountered less often than are malignant neoplasms, as approximately 1,100 malignant tumors of the larynx were observed during this same period. In any discussion of benign tumors of the larynx, there arises the need of defining the term "benign laryngeal tumor." Occasionally, there occur benign new growths, composed of cells which resemble various normal tissue cells but which fulfill
Respiratory tract
Benign tumor
Laryngeal Diseases
Benign neoplasms
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Tuberculoma
Respiratory tract
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Objective To investigate the type and treatment of injury of the larynx.Methods The clinical data of 32 cases of injury in the larynx from 2004 to 2008 were retrospectively analyzed.Results All had satisfactory results.Conclusion Treatment of injury of the larynx should be performed based on different causes and clinical manifestations.
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