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    Vermeidbare Risiken in der medikamentösen Behandlung hochbetagter Patienten
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    Abstract:
    Among 196 patients with a mean age of 80 years there were, at the time of hospitalization, 12.2% who had been prescribed wrong or partly even high-risk medication drugs, some of which carried a high risk. Among 694 prescriptions 4.2% were faulty. The faults consisted of failure to take account of impaired renal function, contraindications, accompanying illnesses, and misinterpretation of side-effects. 80% of these prescriptions were for diuretics, psychoactive and antiarrhythmic drugs, digitalis and hypnotics. The number of faulty prescriptions on discharge was 1.4%. In all, the average number of prescribed drugs had decreased from 3.5 on admission to 2.9 on discharge. This retrospective study demonstrates that the manner of prescribing for elderly patients needs to be handled more critically and rationally.
    Objective To advance prescription quality and standardize prescriptions by analyzing outpatient prescriptions,so as to accommodate the clinic treatment.Methods Judging and analyzing 300 random samples of outpatient prescriptions drew out in the second season in 2010,according to measures for the administration of prescriptions and measures for the administration of prescriptions in hospital.Results There are 144 illogical prescriptions(48.00 percent),114 nonstandard prescriptions(38.00 percent),13 inexact prescriptions(4.33 percent) and 17 excess prescriptions(5.67 percent) in the 300 random samples.Conclusion There is much matter in outpatient prescriptions,and eligible prescriptions are deficient.We shoud study measures for the administration of prescriptions more hard to advance prescription quality and standardize prescriptions,so as to accommodate the clinic treatment.
    Outpatient clinic
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    Digitalis has been used in the treatment of chronic congestive heart failure for 215 years. In this article, numerous clinical studies and trials that have evaluated the efficacy of digitalis in the treatment of patients with congestive heart failure are reviewed. The data indicate that digitalis is a valuable therapeutic agent for relieving symptoms and improving exercise performance and left ventricular function in patients with congestive heart failure. Comparison of the various advantages and disadvantages of digitalis with alternative therapies in patients with congestive heart failure shows an important continuing role for digitalis therapy. (JAMA. 1991;265:2995-2997)
    Whereas the use of digitalis in atrial fibrillation is universally accepted, its administration in patients in sinus rhythm for its inotropic properties has recently been questioned. The risk of digitalis administration is high and may be unavoidable because of the occurrence of changes in sensitivity to digitalis. Benefits of digitalis are poorly defined. Hemodynamically digitalis is a weak inotropic agent. Clinical improvement is difficult to detect; furthermore, the role of long-term maintenance digitalis therapy appears questionable, inasmuch as several studies failed to show deterioration after digitalis therapy has been discontinued.
    Normal Sinus Rhythm
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    OVER one hundred and sixty years ago, Withering1 first described the usefulness of digitalis in the treatment of certain types of "dropsy." About fifteen years later, Ferriar2 first attributed the efficacy of digitalis to its effect on the heart.Early in the twentieth century, the principal use of digitalis was found to be in the treatment of auricular fibrillation (Cushny3 and Lewis.)4 Within the past twenty-five years, however, digitalis has become the drug of choice in the treatment of congestive heart failure of adults with or without auricular fibrillation (Christian,5 Luten,6 Wenckebach7 and Levine8). Digitalizing dosages have been successfully . . .
    Dose
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