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    [Maximal tumor thickness in malignant melanoma].
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    Acral lentiginous melanoma is one type of malignant melanoma,and it is a common cause of misdiagnosis and mortality.Clinical characteristic of malignant melanoma misdiagnosed as diabetic foot ulcer was summarized to remind clinicians of misdiagnosis of malignant melanoma.The need for early biopsy of ulcer,even when clinical suspicion is low,cannot be overemphasized to reduce rate of misdiagnosis and improve survival rate in patients with foot ulcer.
    Acral lentiginous melanoma
    Foot (prosody)
    Diabetic foot ulcer
    Citations (0)
    Rationale: Acral lentiginous melanoma (AML) does not exhibit the classic signs of malignant melanoma. ALM is frequently misdiagnosed because of its unusual sites and atypical clinical morphologies, which lead to poor prognosis. Patient concerns: A female patient aged 78 years was presented to our center with two ulcers on her right foot. Diabetic foot ulcer was considered as the primary diagnosis. The ulcers failed to improve after 2 weeks’ therapy. Diagnoses: An incisional biopsy of the lesion revealed malignant melanoma. Interventions: The patient received wide excision, skin grafting as well as biotherapy. Outcomes: The lesion was healed and no other metastasis has been founded until now. Lessons: Clinicians must maintain a high level of suspicion in distinguishing malignant melanoma from other more benign skin lesions of the foot. The need for early biopsy of ulcer, even when clinical suspicion is low, can not be overemphasized. Only in this way can we reduce misdiagnosis rate and improve survival rate in patients with foot ulcer.
    Foot (prosody)
    Acral lentiginous melanoma
    The main surgical treatment for melanoma consists in wide surgical excision of the primary lesion and the sentinel node but in recent times management of melanoma is rapidly evolving with the introduction of new systemic therapies, like BRAF inhibitors, MEK inhibitors and antibodies anti-PD-1 that show good results in controlling even advanced stages of the disease. This review aims to present data for the optimal surgical management of patients with malignant melanoma.
    Surgical excision
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