Adenoid cystic carcinoma of the Bartholin gland and pregnancy
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Adenoid Cystic Carcinoma
Based on the review of the literature, this paper summarizes some hot issues in research of salivary adenoid cystic carcinoma: (1) perineural invasion of adenoid cystic carcinoma; (2) metastasis of adenoid cystic carcinoma; and (3) prospective therapy of adenoid cystic carcinoma.
Adenoid Cystic Carcinoma
Perineural invasion
Adenoid
Distant metastasis
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Perineural invasion
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Adenoid cystic carcinoma is a malignant tumor of the major and minor salivary glands. Because it grows very slowly, it is often diagnosed at a late stage. The combination of a delayed diagnosis and the tumor's propensity for early perineural and hematologic spread increases the risk of local recurrence and systemic metastasis, often many years after the primary tumor has been diagnosed and treated. Only 80 cases of adenoid cystic carcinoma of the larynx have been previously reported in the literature. We report a new case of laryngeal subglottic adenoid cystic carcinoma in a 12-year-old boy.
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Minor Salivary Glands
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Pulmonary metastases in a 68-year old male was detected 20 years after the operation for adenoid cystic carcinoma originated from external earway. Adenoid cystic carcinoma metastases was confirmed by fine-needle aspiration biopsy from multiple mass lesions in right chest. The pulmonary metastasis of adenoid cystic carcinoma emerging from external earway after such a long period is a rare case in
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Adenoid cystic carcinomas are rare malignant tumors that commonly arise from major and minor salivary glands and are characterized by slow growth, frequent local recurrences, and high incidence of distant metastasis, especially reported in patients with advanced stage tumors. Adenoid cystic carcinomas can rarely occur in other areas of the head and neck region, notably in the nasal cavity. Moreover, adenoid cystic carcinoma limited to the nasal septum is particularly unusual and has been the subject of a small number of published cases only. We discuss here a case of a 42 year-old woman diagnosed with early stage adenoid cystic carcinoma of the posterior nasal septum, treated solely with surgical resection via endoscopic approach. During five years of follow-up, no local recurrence or distant metastasis has been detected.
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Adenoid cystic carcinoma is a rare tumor arising from the minor salivary glands;, the palate being the commonest site. Distant metastasis and perineural invasion areis common in adenoid cystic carcinoma. Diagnosis of adenoid cystic carcinoma is made usually with the help of clinical features, radiographic features and histologic features. We reported a case of adenoid cystic carcinoma of palate involving left maxillary sinus. The diagnosis of the case and brief review of literature of adenoid cystic carcinoma is discussed. The aim here is to highlight the importance of diagnosis, treatment and long-term follow-up of the patients with adenoid cystic carcinoma.
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Perineural invasion
Adenoid
Distant metastasis
Hard palate
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PURPOSE To study the expression and clinical significance of M-phase promoting factor (MPF) in salivary adenoid cystic carcinoma (SACC). METHODS The expression of MPF was investigated in 40 salivary adenoid cystic carcinomas and 40 normal salivary tissues by immunohistochemistry. The expression of MPF was detected in SACC-83 and SACC-LM with Western blot. Pearson's Chi-square test, paired t test and linear correlation analysis were used to analyze the data with SPSS 11.5 software package. RESULTS The expression of MPF was significantly higher in salivary adenoid cystic carcinoma than in normal salivary tissues(P<0.05). There was significant correlation between the level of MPF expression and pathological type(P<0.05). The expression of MPF was significantly higher in SACC-LM than in SACC-83 (P<0.05). CONCLUSIONS MPF highly expressed in salivary adenoid cystic carcinoma, salivary adenoid cystic carcinoma correlated with the expression of MPF and the abnormal activation of MPF was one of the factors for the proliferation of salivary adenoid cystic carcinoma. Metastasis in salivary adenoid cystic carcinoma correlated with the expression of MPF.
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Adenoid cystic carcinoma formerly called cylindroma is rare tracheal tumor. Characteristics of adenoid cystic carcinoma are infiltrative nature with local recurrence tendency and long natural course of the disease. Adenoid cystic carcinomas develop most commonly in the trachea. Primary resection and end-to-end anastomosis of the involved airway are treatment of choice. And postoperative radiation therapy might be useful, particularly when the surgical margins are not ample. We report two cases of adenoid cystic carcinoma of trachea diagnosed by flow-volume curve.
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