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    Stents DonÕt Require Systemic Anticoagulation.But the Technique (and Results) Must be Optimal.
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    showed cardiomegaly on chest X-ray.NYHA functional class>2 was found in 42.2% of TGA pts (NYHA class 3 in 9.3%) and in 50.0% of ccTGA pts (NYHA class 3 in 10.0%).Full criteria for CRT were met in 3.1% of the TGA pts and 5.0% of the ccTGA pts.Including pts in NYHA class 2 and without considering ventricular dilatation (ie.criteria similar to CONTAK CD) 6.3% of TGA and 5.0% of ccTGA pts would have been eligible for CRT.Conclusion: in unselected pts with a systemic right ventricle, 3.1% to 6.3% are potential candidates for CRT.If antibradycardia pacing is indicated, electrical resynchronization may also need to be considered.Prospective studies assessing the logistical and anatomical feasibility of CRT in ACHD cohorts with failing ventricles are warranted.
    Purpose: We aimed to investigate if baseline NTproBNP and clinical variables, predict incident atrial fibrillation (AF) in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI). Methods: From a prospective registry, we assessed 984 PPCI patients. In univariate and multivariate regression analysis, we investigated the association of NTproBNP level determined just prior to PPCI, peri-procedural systolic and diastolic blood pressure, infarct size (maximum CK), gender and age, with the incidence of AF. A Kaplan-Meier curve with quartiles of NTproBNP was computed with a log-rank test to assess for significance of differences. Results: NTproBNP was higher (1297 pg/ml versus 570 pg/ml) in patients with versus without incident AF. In univariate analysis, NTproBNP was significantly associated with incident AF (OR 1,11, 95% CI 1,03-1,21, P=0,009). In multivariate analysis, age was the strongest predictor of incident AF (highest quartiles versus lowest quartile OR 7,04, 95% CI 2,77 -17,87, P<0,001). NTproBNP (OR 1,09, 95% CI 1,00 -1,20, P=0,049), systolic blood pressure (OR 0,98, 95% CI 0,97 -1,00, P=0,021) and infarct size (OR 1,18, 95% CI 1,04 -1,33, P=0,01) were also independently associated with incident AF. Gender, target lesion vessel and diastolic blood pressure were not associated with incident AF. Kaplan-Meier curves (Figure 1) depict that higher NTproBNP quartile is significantly (P=0,001) associated with incident AF. Figure 1. Kaplan-Meier curves Conclusion: Age is strongly predictive for incident AF in STEMI patients undergoing PPCI. NTproBNP and infarct size are also independent predictors of incident AF, whereas peri-procedural systolic blood pressure is inversely related to incident AF.
    Background: Arrhythmogenic cardiomyopathy (AC) primarily affects the right ventricle but left ventricular (LV) involvement is common. Nevertheless, 12-lead electrocardiography characteristics of LV involvement have not been studied. Our aim is to assess ECG features of LV involvement in AC. Methods: In a cohort of 51 patients with AC (39 males; mean age 47.6 ± 15.2 years) there were 32 patients with LV involvement (62 %). The association of depolarization and repolarization ECG abnormalities were analysed in patients with or without LV involvement in a cross-sectional design study. Results: As appreciated in the table, T wave inversion in V4-V6 was not associated with the presence of LV affection in the echocardiogram. QRS tended to be wider, and more fragmentated in patients with exclusive right ventricular disease compared to those with LV involvement. We found no ECG feature with clear ability to predict LV disease. Conclusion: Inferior and lateral ECG leads abnormalities do not predict the presence of LV involvement in patients with AC, against previously published diagnostic criteria. Moreover, QRS was slightly wider and more fragmented in V1-V3 in patients with exclusive right ventricular affection, suggesting a possible predominant left ventricular disease in cases of biventricular dysplasia.
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    This study was performed to determine the relation between inducible sustained ventricular tachycardia (ISVT) by programmed electrical stimulation and angiographic, clinical and echographic data in patients with coronary artery disease. The aim of this study was to explore if these inducible arrhythmias are associated with any specific "arrhythmogenic" pattern of coronary artery disease. 129 consecutive patients with coronary artery disease and ISVT were evaluated by left ventriculography and coronary arteriography by standard techniques. The mean age of the patients was 46 years with a range of 21 to 72 years, 74% of them were males. A significant stenosis of the main left coronary artery (>50%) appeared to be more frequent in arrhythmia patients (31%). Also proximal left anterior descending artery stenosis was more frequent in in the arrhythmia patients (48%). "Main left equivalent" lesions, defined as a significant stenosis of the proximal left anterior descending artery and the proximal left circumflex artery was significantly more frequent among the arrhythmia patients (51%). Using the quantitive wall motion analysis, a strong relationship was found between the number of abnormally contracting segments and the presence of inducible sustained ventricular tachycardia. The results of the present study suggest that ISVT in patients with coronary artery disease are more frequently associated with lesions of the main left coronary artery or the proximal left anterior descending artery.
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