[Primary osteochondroma of the lung; hamartoma].
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Hamartoma
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Abstract Spinal harmatoma is an extremely rare tumor, and only 16 cases have been reported previously. We report on a 73‐year‐old woman with low back pain because of spinal hamartoma. To our knowledge, the current report is the first published case of a spinal hamartoma without other systemic diseases in the aged.
Hamartoma
Spinal Surgery
Back Pain
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Hamartoma
Nasal vestibule
Orbit (dynamics)
Ethmoid sinus
Vestibule
Sinus (botany)
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骨軟骨腫は原発性骨腫瘍の中では発生頻度が高い良性腫瘍で，四肢長幹骨の骨幹端部に好発するが，脊椎に発生することはまれである．今回胸椎に発生し脊髄症状を呈した骨軟骨腫の1例を経験したので報告する．症例は16歳男性である．野球の練習中に左膝崩れを生じ，当院の救急外来を受診された．初診時は膝半月損傷を疑い，精査を行ったが，膝関節に異常を認めなかった．その後両下肢に脱力感を生じ歩行困難となった．脊髄疾患を疑い精査を行ったところ，第8胸椎上関節突起に骨腫瘍を認めた．腫瘍は脊柱管内に突出し，脊髄を高度に圧迫していた．歩行障害が進行し，腫瘍切除を施行した．術後は両下肢の痙性は残存しているが，歩行障害は徐々に改善している．病理診断は骨軟骨腫であった．
Thoracic spine
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Intraspinal osteochondroma is rare. Only 29 intraspinal osteochondromas were reported in the Bone Tumor Registry in Japan from 1972 to 1992 and this accounts for 0.4% of all osteochondromas.We report a case of intraspinal vertebral osteochondroma causing thoracic myelopathy. An 8-year-old boy was noticed to fall down easily on gait by his mother. He showed spastic gait, and one week later he had difficultly in walking progressively. Neurological examination revealed hyperreflexia of both lower extremities, right ankle clonus, positive Babinski signs, and sensory change under the level of Th4. A myelogram demonstrated a right lateral extradural mass with complete spinal block at Th1. Computed tomogram (CT) demonstrated an osseous mass arising from the right facet of Th1/2. A right hemilaminectomy of Th1 was carried out, and the osseous mass including the right superior articular facet of Th2 was excised. No spinal fusion was performed. Histopathologically, it was determined to be a benign osteochondroma. Eight months after surgery, neither recurrence of the tumor nor instability of the spine was seen.
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Exostosis
Thoracic spine
Hyperreflexia
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Hamartoma
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Objective Summarize the clinic features, the experience of surgical treatment and prognosis of the pulmonary hamrtoma. Method A retrospective study of 30 cases treated by operation, clinical characteristics, imaging for pulmonary hamartoma confirmed by pathology and operation characteristics of the experience. Result 30 cases of 20 patients without clinical symptoms, all groups underwent operation treatment, follow-up of 20 cases without recurrence and malignant change of a case.The misdiagnosis rate was 80%(24/30).Conclusion Pulmonary hamartoma is a better a benign tumor prognosis, confirmed by pathological diagnosis. Minimally invasive thoracoscopic operation than conventional open chest operation has more advantages in tumor.
Hamartoma
Benign tumor
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Background: Anatomical lung resection offers the best chance of cure for patients with localized lung cancer.Very often late diagnoses, advanced stage of the disease limit radical anatomical surgical resection.Use of neoadjuvant chemotherapy made some of the cases operable, and later they were surgically treated.Aim: to evaluate early (surgical) complications at patients with neoadjuvant therapy. Material and Methods:We compare 36 patients surgically treated with lung resection, before treated with neoadjuvant chemotherapy (3 to 6 cycles with platinum based regiments under protocol) with 42 patients surgically treated without neoadjuvant chemotherapy, in the same period, in the 2009 and 2010.Results: At the group with neoadjuvant chemotherapy we register more intraoperative and early postoperative complications as: bleeding 10 vs. 7, p=0.63, changes in lung vessels 3 vs.0, p=0.8, prolonged air leak 9 vs. 6, p=0.63, stump fistula (at pneumectomy patients) 2 vs. 0, p=0.76, pneumonia 9 vs. 3, p=0.86,wound infection 2 vs 0, p=0.73, atelectasis 8 vs. 2, p=0.88, prolonged pleural drainage 10 vs. 4, p=0.87.There, also, was no difference in 30 days mortality rate between groups. Conclusions:Neoadjuvant therapy increased theperioperative complications in this group of patients compared with a similar group undergoing anatomical lung resection in the same institution.The most common complication in patients receiving induction chemotherapy was detected at the group with neoadjuvant chemotherapy.Strategies to prevent these complications will be important, especially if chemotherapy before resection becomes the standard for all patients with non-small cell lung cancer. OPEN
Neoadjuvant Therapy
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