Adenoid cystic carcinoma of breast
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Adenoid Cystic Carcinoma
Breast carcinoma
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Abstract A review of submaxillary gland neoplasms over a 21 year period revealed 15 malignancies and 7 benign tumors. All of the malignancies occurred in females, and 11 of these were adenoid cystic carcinoma. Two of the 11 were found to have infiltrating ductal carcinoma of the breast (1 pre and 1 postdiagnosis of the submaxillary carcinoma) and 3 had benign breast disease. While previous reports have suggested an association of parotid gland neoplasia and breast cancer, this is the first known report of an association between adenoid cystic carcinoma of the submaxillary gland and cancer of the breast. The discussion of adenoid cystic carcinoma of the submaxillary gland emphasizes the increased frequency of this disease in females, its association with breast disease, and also experimental submaxillary gland neoplasia.
Adenoid Cystic Carcinoma
Submaxillary gland
Breast carcinoma
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An example of a cribriform intraductal carcinoma that closely resembled adenoid cystic carcinoma is described. The true nature of the tumor was revealed by electron microscopy and the case is used to demonstrate that the diagnosis of this tumor cannot be safely made by routine histologic techniques alone. Review of conflicting views othe value of mucin histochemistry expressed in the literature suggest that ultrastructural examination is a useful alternative tool in the differentiation of adenoid cystic carcinoma of the breast from cribriform intraductal carcinoma.
Adenoid Cystic Carcinoma
Cribriform
Breast carcinoma
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乳腺伴有癌的腺肌上皮瘤属于罕见肿瘤，该文报道1例70岁女性病例。乳腺单发病灶，界不清；镜下肿瘤细胞向周围脂肪组织内浸润性生长，呈现多种细胞形态，主要是典型腺上皮及肌上皮增生形成的双层套管结构，并可见实性巢状及筛状结构；部分区域细胞异型增生，核分裂象增多，>10个/10 HPF，可见坏死。免疫表型：雌激素受体、孕激素受体、HER2均阴性；Ki-67阳性指数20%；广谱细胞角蛋白在腺细胞强阳性，而肌上皮细胞弱阳性；细胞角蛋白5/6、Calponin、平滑肌肌动蛋白、S-100蛋白、p63在肌上皮阳性表达。乳腺伴有癌的腺肌上皮瘤具有一定的组织学特征。诊断主要依靠病理形态学及免疫组织化学标记。.
Adenoid Cystic Carcinoma
Breast carcinoma
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Invasive carcinoma in the axilla may arise from skin appendage glands or ectopic breast tissue or it may be a metastasis. Carcinomas of the skin adnexal glands and breast can be difficult to distinguish from each other as they often display the same patterns of growth. Tubular, cribriform, papillary, apocrine, mucinous, and adenoid cystic are histologic types of carcinoma seen in the breast and skin appendage glands. To our knowledge, secretory carcinoma, the most common form of mammary carcinoma in children, has not yet been described as a morphologic pattern of skin adnexal carcinoma, although we cannot exclude the possibility that such a case was reported with a different diagnosis. We report a case of a young girl with secretory carcinoma that seems to have arisen from skin appendage glands in the skin of the axilla in the absence of demonstrable ectopic breast tissue.
Apocrine
Axilla
Adenoid Cystic Carcinoma
Breast carcinoma
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Adenoid Cystic Carcinoma
Breast carcinoma
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Three cases of adenoid cystic carcinoma have been identified in a 10-year review of 2686 cases of breast carcinoma. The criteria necessary for diagnosis have been reviewed with particular reference to cribriform intraduct carcinoma and adenocarcinoma of the breast with small, dark, 'basaloid'-cell pattern. The most important single diagnostic criterion of adenoid cystic carcinoma is a biphasic cellular pattern which may be aded by the demonstration of two types of mucin stromal acid mucopolysaccharide and ductal neutral mucopolysaccharide. This tumour most frequently presents as a painful or tender mass near the areola, and it carries a uniquely favourable prognosis when compared with similar tumours elsewhere in the body. Actomyosin has been demonstrated in all three tumours by an immunofluorescent method, and this supports a predominantly myoepithelial origin.
Adenoid Cystic Carcinoma
Histogenesis
Cribriform
Breast carcinoma
Adenoid
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Abstract Triple-negative breast carcinomas constitute a wide spectrum of lesions, mostly being highly aggressive. Nevertheless, some special histologic subtypes can have low malignant potential. The purpose of the present paper is to review diagnostic criteria and prognostic parameters of breast neoplasms of special histotypes. Specifically, adenoid cystic carcinoma, adenomyoepithelioma, acinic cell carcinoma, mucoepidermoid carcinoma, tall cell carcinoma with reverse polarity, and secretory carcinoma will be discussed. For each tumour, definition and morphological and molecular features, together with prognostic parameters, will be presented. Paradigmatic cases will be illustrated.
Acinic cell carcinoma
Adenoid Cystic Carcinoma
Breast carcinoma
Metaplastic Carcinoma
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Metaplastic Carcinoma
Adenoid Cystic Carcinoma
Spindle cell carcinoma
Breast carcinoma
Adenoid
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Adenoid Cystic Carcinoma
Chromogranin A
Synaptophysin
Breast carcinoma
CD117
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ReportSUMMA RY: Adenoid cystic carcinoma of the br east is a maligna nt tumour of significant incidence with a better prognosis than histoiogica ll y identical tumours occurring in other sites and as compared to other malignant tumours of the breast.The recognition of the tumour is important especially in the management of the individual patient but also in further ing understanding of gr owth , spr ead and biological behaviour of tumours.
Adenoid Cystic Carcinoma
Breast carcinoma
Adenoid
Breast Tumours
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