Analyzed the treatment effect of advanced gastric cancer about S-1 and Capecitabine combined with oxaliplatin
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Abstract:
Objective Comparative analysis the treatment effect of postoperation recurring gastric cancer about S1 and Capecitabine combined with Oxaliplatin. Methods The 26 patients which were postoperation recurring gastric cancer received and cured.Observed group (12 cases)cured with Oxaliplatin 30 mg/m2,D1, intravenous drip,S-1 selected 40mg～60mg/times about body surface area, 2 times/d, oral administration, D1~D14.Matched group (14 cases)cured with Oxaliplatin 30 mg/m2, D1, intravenous drip; Capecitabine applied 1500mg/times, 2 times/d, oral administration, D1~D14.Both the methods remedy cycles were 21 days.Effected assessment one times with two cycles, and follow-up visited the patients' condition.Results All the patients can be evaluated, the observed group's RR was 50% and the matched group's RR was 42.8%, they had no significant differences, but adverse effects and serious reactions of observed group were clearly under the matched group.Conclusion S-1 combined with Oxaliplatin was effective on advanced gastric cancer, and the adverse effects were tolerable.Keywords:
Tegafur
Body surface area
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