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    The analysis on drug resistance of mycobacterium tuberculosis for tuberculosis patients in Sichuan province
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    Abstract:
    Objective To understand the status on drug resistance of mycobacterium tuberculosis in Sichuan,and to provide the evidence for tuberculosis treatment and control.Methods The tuberculosis patients were investigated by face to face interview and the clinical isolates of patients were collected.Mycobacterium tuberculosis were identified,and absolute concentration method was used to test the drug-resistance of isoniazide(INH),rifampicin(RFP),streptomycin(SM),ethambutol(EMB).The status on drug resistance of mycobacterium tuberculosis were analyzed.Results The total rate of drug resistance and the rate of multi-drug resistance were respectively 21.39% and 11.35%,and there was statistical significance between the total rate of drug resistance and multi-drug resistance of primary treatment patients and that of re-treatment patients.Conclusions There is a decrease in the drug resistant status of Sichuan,but it is still an importance of tuberculosis control and prevention,and we should further strengthen on its surveillance and control.