EFFECT OF THE SUPPLEMENTATION OF ZINC AND/OR MICRONUTRIENTS ON CHILDREN'S PHYSICAL DEVELOPMENT.
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Objective: In order to investigate the effect of zinc and/or micronutrients compound intervention on the physicaldevelopment in pre-school children. Methods: 480 children were divided into 3 groups: zinc group, micronutrients group, zincplus micronutrients group. During the experiment of 10 weeks, the children were supplied with zinc, micronutrients or zinc plusmicronutrients respectively. Results: The data showed that the increases of children's height and weight were significantly higherin micronutrients and zinc plus micronutrients groups than those in zinc group. Conclusion: it suggests that the supplementationof mieronutrients compound should promote children's growth and development, and that attention should be paid to the supplementation of other nutrients while zinc be supplied for children.Topics:
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Before and after zinc and micro-nutrients supplement the changes of intelligence and growth in 108 healthy children aged 7～8yrs were studied.The children were randomly divided into 3 groups:zinc supplement(Z),zinc+micronutrients supplement(Z+M),and micronutrients supplement(M),Before the supplements,hair Zn contemt of children was 2 28±0 74μmol/g and 22 22% of the hair Zn content was lower than 1 68μmol/g?There was a positive correlation between intelligence quotient(IQ) and hair Zn content .After supplement,there were no significant changes among the 3 groups on hair Zn content .The changes of IQ and cognition in Z+M group and M group were significantly higher than Z group,and there was no significant difference between Z+M group and M group.The change of knee height in Z+M group was markedly higher than M group and Z group,while M group was sgnificantly higher than Z group.The results demonstrated that zinc deficiency might not be the main factor that affects the intelligence and growth children,perhaps other micronutrients deficiency should be paid more attention.The simultaneous supplement of zinc and micronutrients may promote the intelligence and growth of children.
Micronutrient deficiency
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To study the effect of multi-micronutrients supplementation on nutritional status of children, 220 students aged 8-12 years were observed for 6 months. A half of them were given the supplements, another half placebo. The results showed that in comparison with the placebo, the supplemented children had a higher urine excretion of vitamin B2 and vitamin C after loading; a higher concentration of serum 25-OH-D3, a high content of hydroxy-proline and hydroxy-proline/creatinine ratio in fast urine, and a higher bone mineral content and bone mass density of the mid-ulna. The supplemented children performed significantly better than the placebo in reading speed, learning capacity and arithmetic examinations. It is concluded that micronutrients supplementation played a notable rule in resulting better nutritional status and learning ability of school children.
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Childhood zinc deficiency is a common problem in many developing countries where people rely mainly on plant based diets with low zinc contents. Zinc supplementation is one of strategies to combat zinc deficiency and its consequences in children. The aim of this community trial was to examine the effect of zinc supplementation on the linear growth of children 6-24 months of age and to examine the feasibility of its implementation in the context of primary health care (PHC).
Multivitamin
Linear growth
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Carotene
Micronutrient deficiency
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Micronutrient deficiency
Linear growth
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Food fortification
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The Galle Medical Journal is published by the Galle Medical Association. The journal is published quarterly in March, June, September and December each year. The submissions are accepted throughout the year. The aims of the Journal are to foster co-operation among the medical fraternity and to be a forum to make literary contributions, share experiences encountered in medical practice, update their knowledge and have debates on topics related to all aspects of medicine.
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Medical journal
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Regimen
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Fortifying rice with multiple micronutrients could be a promising strategy for combat micronutrient deficiencies in developing countries. We determined the efficacy of extruded rice grains fortified with multiple micronutrients on the prevalence of anemia, micronutrient status, and physical and cognitive performance in 6- to 12-y-old, low-income school children in Bangalore, India. In a randomized, double-blind, controlled trial, 258 children were assigned to 1 of 3 intervention groups to receive rice-based lunch meals fortified with multiple micronutrients with either low-iron (6.25 mg) or high-iron (12.5 mg) concentrations or identical meals with unfortified rice. The meals were provided 6 d/wk for 6 mo. Anthropometric, biochemical, physical performance, and cognitive assessments were taken at baseline and endpoint. At baseline, study groups were comparable, with 61% of the children being anemic. However, only <10% were deficient in iron, vitamin A, and zinc. After 6 mo, plasma vitamin B-12 and homocysteine concentrations (both P< 0.001) as well as physical performance (P< 0.05) significantly improved in the intervention arms. No between-group differences were observed in hemoglobin concentration, anemia, and deficiencies of other micronutrients or cognitive function after 6 mo, but paired analyses revealed a small reduction in anemia prevalence in children in the low-iron group. The fortified rice was efficacious in improving vitamin B-12 status and physical performance in Indian school children.
Biofortification
Micronutrient deficiency
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Objective:To determine effects of zinc intervention on the absorption of dietary iron.Methods:520 pre school children aged 6 to 7 years(equal numbers of boys and girls),who were divided randomly into 4 groups:zinc supplement group,zinc plus micronutrient supplement group,micronutrient supplement group and control group.The experiment lasted for 10 weeks.Before and after zinc and micronutrients supplemented,blood samples were analyzed for haemoglobin(HB).Results:The observations showed that the concentration of HB in micronutrient supplement group is significantly higher than the others( P0 05 ),the absorption of dietary iron is affected apparently by micronutrients.Conclusion:Attention should be paid to the supplementation of other nutrients before choosing some micronutrients be supplied of dietary for child.
Dietary iron
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