Accuracy of endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) of solid pancreatic tumours
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Abstract:
EUS is one of the most important tools in the staging of pancreatic tumours and with the linear-array instruments FNA can be performed if malignancy is suspected. We prospectively investigated the diagnostic accuracy of the EUS FNA in our series.Keywords:
Endoscopic Ultrasound
Endoscopic Ultrasound
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Aims It is still unclear whether endoscopic ultrasound (EUS) contrast-enhanced Harmonic fine-needle aspiration (CH-EUS-FNA) determines superior results in comparison to standard EUS-FNA in tissue acquisition of pancreatic masses. The aim was to compare the pooled diagnostic performances of these two techniques.
Endoscopic Ultrasound
Pancreatic mass
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Endoscopic Ultrasound
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Since the development of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the early 1990s, its application has been extended to various diseases. For pancreatic cancer (PC), EUS-FNA can obtain specimens from the tumor itself with fewer complications than other methods. EUS-FNA can also be more useful for TNM staging than other imaging modalities. Furthermore, EUS-FNA can contribute to precision medicine by obtaining tissue for immunohistochemical or genetic studies from primary or metastatic sites of diseases. This paper will focus on the role of EUS-FNA in PC.
Endoscopic Ultrasound
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Purpose: Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is a potential method to diagnose pancreatic mass, but factors associated with the accurate cytological result of EUS-FNA in pancreatic solid tumor are not well known. The aim of this study was to evaluate the yield of EUS-FNA and clinical factors which might have influence on the accuracy of the result of EUS-FNA, such as physicians, location of mass, the number of needle passage attempts and size of mass.
Endoscopic Ultrasound
Pancreatic mass
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Endoscopic Ultrasound
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The aim of the study is to evaluate the extent to which patients acquired necessary knowledge about pancreatic endoscopic ultrasound-guided fine needle aspiration and assess what should be more focused on in the informed consent process.Adult patients enrolled in this study had pancreatic lesions confirmed by regular imaging and planned to undergo the first pancreatic endoscopic ultrasound-guided fine needle aspiration. These patients were asked to complete a questionnaire, including indications, possible results, downstream events, the risk for false-negative and malignant lesions, and so on. Then we conducted a longterm follow-up of these patients to obtain the final results.Most people (94.25%) correctly recognized that the indication of pancreatic endoscopic ultrasound-guided fine needle aspiration was to exclude malignant lesions. Almost all patients knew that the results could be benign or malignant, while the number of people who were aware of non-diagnostic (22%), indeterminate (18%) outcomes, and the possibility of further testing (20%) after the endoscopic ultrasound-guided fine needle aspiration has decreased significantly. Finally, we got that the false-negative rate and percentages of malignancy were 17.81% and 83.91%, while 98% of participants did not recognize that there is a false-negative risk of endoscopic ultrasound-guided fine needle aspiration and more than 2/3 of participants did not know how much risk they might have for malignant lesions.A high proportion of patients who received endoscopic ultrasound-guided fine needle aspiration could identify the indication for this procedure but remained unaware of possible outcomes, downstream events, especially the risk for false-negative and malignant lesions. It is necessary to improve the quality of dialogue between clinicians and patients, and the information about the risk of false-negative and malignancy may need to be emphasized in the informed consent process.
Endoscopic Ultrasound
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Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a standard procedure for precise histological diagnosis of pancreas tumors, but it is sometimes difficult to obtain adequate specimens. EUS Sonopsy CY® is a newly designed needle with original features. This randomized study will compare the tissue collection rate of EUS Sonopsy CY® to that of a conventional needle in EUS-FNA. The major eligibility criteria are as follows: Patients with a pancreatic mass referred for EUSFNA; age 20 years, and performance status＜4. The primary outcome is the tissue collection rate. This study will elucidate the efficacy of EUS Sonopsy CY®.
Endoscopic Ultrasound
Pancreatic mass
Fine needle biopsy
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Endoscopic Ultrasound
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Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is widely performed to diagnose pancreatic masses. Recently 25-gauge needle (25G) is available, which is thinner and more flexible than 22-gauge needle (22G) for EUS-FNA. Smaller needle, like a 25G might provide less bloody component, less complications and more safe and easier to maneuver than using larger needle. The aim of this study was to compare efficacy of 25G with 22G in EUS-FNA for pancreatic tumor.
Endoscopic Ultrasound
Pancreatic mass
Bloody
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