Vulvar hidradenoma papilliferum (HP) is located on the sites of mammary-like anogenital glands (MLAGs): Analysis of the photographs of 52 tumors
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Hidradenoma
Vulvar neoplasm
Anogenital distance
We report a case of hidradenoma papilliferum of the vulva. A 70-year-old woman was admitted to our hospital with a vulvar tumor. Cytologic smear examination revealed seat-shaped tumor cells. The nuclei contained uniformly distributed fine granular chromatin. Around the seat, cells with thin concentrated chromatin were detected. Subsequently, local excision was performed. Histological findings of the resected specimen showed that the tumor was composed of cells organized in tubular and papillary structures. The tumor contained epithelial cells with apical snouts and p63-positive myoepithelial cells were observed on immunostaining. Apocrine metaplasia was detected. No mitotic figures or atypical nuclei were observed.
Hidradenoma
Papillary tumor
Vulvar neoplasm
Immunostaining
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Hidradenoma
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Hidradenoma
Benign tumor
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Hidradenoma
Apocrine
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Benign and malignant tumours may arise from eccrine and apocrine sweat glands. Hidradenocarcinoma is a rare malignant eccrine sweat gland tumour representing <0.01% of all skin cancers. There are 6 case reports in the literature of hidradenocarcinoma arising on the vulva, none of which are classified as poroid hidradenocarcinoma. Hidradenocarcinoma is thought to be an aggressive tumour with poor prognosis and high levels of local recurrence and systemic metastases. Conversely, hidradenoma papilliferum is a common benign apocrine sweat gland tumour found on the vulva. The prevalence and significance of atypical changes, however, is unknown. Distinguishing between these tumour types can be difficult. The authors present two cases, a poroid hidradenocarcinoma and an atypical hidradenoma papilliferum with necrosis and increased mitotic activity, to illustrate the diagnostic challenges associated with rare tumours of the vulva in the absence of an established histopathological classification system.
Hidradenoma
Apocrine
Eccrine sweat gland
Vulvar neoplasm
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The hidradenoma of vulva is a rare tumor. After description histogenesis and microscopic appearance demonstrated histological difficulties. An exact microscopic diagnois is necessary because the hidradenoma is a benign tumor.
Hidradenoma
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Hidradenoma
Labia Minora
Apocrine
Intraductal papilloma
Labia
Vulvar neoplasm
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Abstract Malignant nodular hidradenoma (MNH) of vulva is a rare entity. It is a malignant primary skin tumour of eccrine sweat glands and is aggressive in nature. We are reporting this case of 28-year-old primigravida with 38 weeks pregnancy who presented with a vulval swelling and histopathology report of malignant nodular hidradenoma of vulva. Imaging studies showed metastatic disease. Patient was managed with chemotherapy after three weeks of vaginal delivery followed by surgery and chemotherapy, but tumour recurred and is planned for second line chemotherapy. Malignant nodular hidradenoma (acrospiroma) is a rare vulval tumour. Early diagnosis and excision with adjuvant chemotherapy is imperative. Keywords: Vulva, Hidradenoma, Metastasis, Chemotherapy
Hidradenoma
Histopathology
Vulvar Carcinoma
Vulvar neoplasm
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Five cases of hidradenoma of the vulva are reported. The differential diagnosis is discussed. Painstaking microscopic diagnosis is very important since the hidradenoma may be confused with an adenocarcinoma. Local excision of the small tumour is the only treatment necessary.
Hidradenoma
Vulvar neoplasm
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