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    A Study on the Stimulated Salivary Flow Volume of Cerebrovascular Accident Patients : 2 : Comparison among Groups of Healthy and Elderly Subjects and Cerebrovascular Accident Patients
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    Accident (philosophy)
    Ischaemic stroke
    Stroke
    Citations (13)
    Cerebral blood flow in relation to change in arterial pressure was measured in 11 elderly patients with postural hypotension. Seven patients with symptoms showed bilateral or unilateral failure of cerebral autoregulation, while the four asymptomatic patients did not. Variations in cerebral autoregulation would explain why some elderly people with minor falls of systemic arterial pressure develop clinical signs of cerebral ischaemia whereas others with greater falls in blood pressure remain asymptomatic. Elderly patients with impaired autoregulation may be at risk of brain damage from minor falls in blood pressure.
    Cerebral autoregulation
    Cerebral ischaemia
    Pure autonomic failure
    Citations (130)
    Medical examinations were used to classify 271 adults aged 18-77 into 6 groups: normotensive, treated and untreated hypertensive, coronary heart disease (CHD), transient ischemic attack (TIA), and recovered stroke. They were also divided by age into 3 groups: 18-36, 37-55, and over 55 years. Each subject completed 12 reaction time (RT) tasks which involved making 16 consecutive responses without interruption. Serial RT increased with age throughout the lifespan. RT was also increased in treated hypertensive patients; this slowing was unrelated to type of drug treatment. Patients with cerebrovascular disorders showed greater slowing and also made more errors; TIA patients showed greatest impairment. No significant performance deficits were observed in untreated hypertensive or CHD groups. However, a trend toward slowing among untreated hypertensive patients with high plasma renin activity was observed. Behavioral deficits associated with both aging and diagnosed vascular disorders were interpreted as evidence of impaired brain function.
    Stroke
    Hypertensive disease
    Hypertensive heart disease
    Citations (54)
    31例のパーキンソン病において, 脳MRI上ラクネの頻度を明らかにし, 同時にラクネの関連因子である年齢, 随時血圧, 24時間平均収縮期血圧, ドップラー法による総頸動脈血流を検討した. ラクネの定義は, T1強調画像で低信号かつT2強調画像で高信号を示す直径1cm以下の病巣とした.パーキンソン病31例中19例 (61%) にラクネを認めた. ラクネの部位としては, 大脳深部白質, 基底核, 脳幹部の順に頻度が高かった. ラクネを有するP (+) 群は, ラクネを認めないP (-) 群に比して有意に年齢が高かった. 両群間に重症度, L-dopa 服用量に有意差はなかった. P (+) 群とP (-) 群の間に, 随時血圧については有意差を認めなかったが, 24時間平均収縮期血圧は, 年齢とは独立に, P (-)群に比してP (+) 群で有意に高値を示した. また, ドップラー法による総頸動脈血流も, P (-) 群に比してP (+) 群が有意に低値を示したが, これは血圧よりもむしろ加齢の影響が示唆された.以上の結果より, 老年者パーキンソン病でも, 潜在性のラクネが予想以上に認められ, アルツハイマー型老年痴呆でいう「混合型」のような概念の存在が想定された. その危険因子としては, 加齢の影響と, 随時血圧ではなく24時間平均収縮期血圧が影響している可能性が示唆された.
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    Cerebral blood flow (CBF) was studied at normocapnia and after a challenge with 5% CO2 in 59 diabetic patients and 28 controls. There was a significant age-related decline in CBF in both groups, which suggests that diabetes does not affect the rate of decrease of CBF with age. After CO2 challenge CBF increased in most of the controls; in the patients CBF increased in 23, decreased in 26, and remained stable in 10. Thus the reactivity of cerebral blood vessels in diabetics is altered. Diabetics have diminished cerebrovascular reserve and are thus at increased risk of cerebrovascular disease because they are unable to compensate when necessary with an increased CBF.
    Normocapnia
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    뇌졸중의 발생빈도가 증가하는 추세에 따라 뇌출혈과 뇌경색, 마비부위 그리고 성별을 중심으로 신체조성 변화의 차이를 조사해 뇌졸중 유형에 미치는 영향을 분석하여 뇌졸중 환자의 발병 원인과 특성에 알맞는 중재를 실시하기 위한 기초 자료를 제공하는데 연구의 의의가 있으며, 물리치료를 실시하여 뇌졸중 환자의 체성분 변화를 검증한 결과 물리치료 실시 후 남자 환자 집단과 좌측 부위 마비 환자 집단에서 근육량의 변화를 보여, 뇌졸중 환자의 신체조성의 변화를 위해서는 물리치료를 적용하고, 앞으로의 연구에 기초자료로 활용되기를 바라며, 지속적인 물리치료 재교육 프로그램을 실시하는 것이 중요하다. Purpose of this study was to investigate the effect of cerebrovascular accident patients who divided cerebral hemorrhage and cerebral infarction as a result of body composition. cerebral infarction patients of cerebrovascular accidents were observed the higher ratio than cerebrovascular hemorrhage patients. Experimental group were sixteen subjects who had received. We used experimental instruments such as inbody to measurement body composition. The result were as follows; 1. There was no significant difference between two groups regarding Change in body composition according to the come of onset. 2. Change in body composition according to the sex, the soft lean mass were significantly different (p<.05). But the other variations were not significantly different between two groups. 3. Regarding the change in body composition according to the region of paralysis, the soft lean mass differ significantly(p<.05). But the other variations did not differ significantly between two groups.
    Stroke
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    Increased incidence of orthostatic hypotension and presyncopal symptoms in young women could be related to hormonal factors that might be isolated by comparing cardiovascular and cerebrovascular responses to postural change in young and older men and women. Seven young women, 11 young men, 10 older women (>1 yr postmenopausal, no hormone therapy), and 9 older men participated in a supine-to-sit-to-stand test while measuring systemic hemodynamics, end-tidal Pco(2), and blood flow velocity of the middle cerebral artery (MCA). Women had a greater reduction in stroke volume index compared with age-matched men (change from supine to standing: young women: -22.9 ± 1.6 ml/m(2); young men: -14.4 ± 2.4 ml/m(2); older women: -17.4 ± 3.3 ml/m(2); older men: -13.8 ± 2.2 ml/m(2)). This was accompanied by offsetting changes in heart rate, particularly in young women, resulting in no age or sex differences in cardiac output index. Mean arterial pressure (MAP) was higher in older subjects and increased with movement to upright postures. Younger men and women had higher forearm vascular resistance that increased progressively in the upright posture compared with older men and women. There was no difference between sexes or ages in total peripheral resistance index. Women had higher MCA velocity, but both sexes had reduced MCA velocity while upright, which was a function of reduced blood pressure at the MCA and a significant reduction in end-tidal Pco(2). The reductions in stroke volume index suggested impaired venous return in women, but augmented responses of heart rate and forearm vascular resistance protected MAP in younger women. Overall, these results showed significant sex and age-related differences, but compensatory mechanisms preserved MAP and MCA velocity in young women.
    Supine position