Clerodane-type diterpenoids from tuberous roots of Tinospora sagittata (Oliv.) Gagnep
Geng ZhangHaoran MaSong HuHongfeng XuBo YangQuanwei YangYongbo XueCheng LüJie JiangJinwen ZhangFuqian WangYonghui Zhang
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Menispermaceae
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Conducts the systematic observation on leaf venational patterns of 7 general and 13 species of Menispermaceae in Fujian Based on their different characteristics, the menispermaceae leaf venations are divided into three type: actinodromous, palinactinodromous and acrodromous The division of venational patterns don't relate to genera These species venational characteristics distinct from each other in a number of primary vein, ramified, the secondary veins' angle of divergence and behaviour And these distinctive characteristics are steady, which indicate that the leaf venational of menispermaceae have significance for the delimitation of species These paper also provide additional evidence for evolution of menispermaceae
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Jateorhiza macrantha (Hook. f.) Exell and Mendonça (Menispermaceae) is a common medicinal plant found in tropical Africa. Jateorhiza macrantha is used as an anti-hemorrhagic, to combat syphilis and headache [1]. This study was performed to evaluate the analgesic and anti-inflammatory activity of extract.
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Two new morphinane alkaloids named cephamonine (1) and cephamuline (2) were isolated from the tuber of Stephania cepharantha HAYATA (Menispermaceae), cultivated in Japan, along with eleven known alkaloids. By comparison of spectroscopic data with those of sinomenine (3), the structures of 1 and 2 were elucidated to be the 8-methoxy derivative of 3 and its C-14 stereoisomer, respectively.
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Nine isoquinoline alkaloids belonging to the protoberberine, proaporphine and bisbenzyl-isoquinoline series were isolated from Caryomene olivascens (Menispermaceae). Four compounds are new : (-)-2-norlimacine (4), (-)-caryolivine (6), (+)-1, 2-dehydro-2-norlimacusine (9) and N-formylstepharine (3). The last one is the first N-formyl derivative to be reported in the proaporphine group. Its biogenetic origin is discussed. Structures were established on the basis of 360 MHz (FT) nuclear magnetic resonance measurements and also by chemical correlation in the case of 3.
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Nodosin, a new diterpenoid isolated from Isodon trichocarpus KUDO and I. Japonicus HARA, was converted to the keto lactone acetal X via several steps of reactions. The conversion made it possible to propose the structure II for nodosin. The remaining hydroxyl group proved to be located at C-11 and to have the β-configuration on the basis of a detailed NMR investigation. Thus, the structure and absolute configuration of nodosin were established as formula XIX.
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For thousands of years, plant based herbal medicines have been utilized by millions of people all over the world. Plant materials or products are used in different folk/traditional medical systems, such as the Chinese, African and Indian medical systems, like Siddha, Ayurveda, Unani, and Homeopathy. Tinospora cordifolia (TC) is a medicinal plant belonging to the family Menispermaceae. It is a big deciduous, climbing shrub growing prevalently in the tropical part of Indian subcontinent regions such as India, Pakistan, Nepal, Bhutan, Bangladesh and Srilanka, and in Myanmar, and China. Guduchi, Giloy, Shindilkodi, and Amritha are all the common names for this plant. Extracts from different parts of this herbal plant have been used to treat many diseases. In Ayurvedic medicine, extract from this plant is used for preparing “rasayanas”, which is known to cure diabetes, skin diseases, allergic conditions, jaundice, cardiovascular diseases, rheumatoid arthritis, poisoning, and microbial infections. T. cordifolia has a many bioactive phytochemicals that have been isolated from its aerial parts and roots. Many bioactive principles have been reported from this plant which belong to various classes like alkaloids, aliphatic compounds, diterpenoid lactones, phenolics, flavonoids, glycosides, sesquiterpenoids, lignans, steroids and polysaccharides. T. cordifolia possesses medicinal properties such as antioxidant, antiallergic, antiinflammatory, antimicrobial, antiviral, antidote, antitumor, antileprotic, antispasmodic, and antidiabetic properties. The present review will provide a comprehensive therapeutic potential of T. cordifolia.
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Siddha
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