Pseudo-Gaucher plasma cells in the bone marrow of a patient with monoclonal gammopathy of undetermined significance.

Journal Article Monoclonal Gammopathy in Gaucher's Disease Get access Paul Wolf Paul Wolf Search for other works by this author on: Oxford Academic PubMed Google Scholar Laboratory Medicine, Volume 4, Issue 8, 1 August 1973, Pages 28–29, https://doi.org/10.1093/labmed/4.8.28 Published: 01 August 1973

Monoclonal gammopathy

Paraproteinemias

Gammopathy

10.1093/labmed/4.8.28

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Citations (12)

IgM monoclonal gammopathy/Waldenström's macroglobulinemia: a morphological and immunophenotypic study of the bone marrow.

PubMed (1990)

Feiner Hd Rizk Cc Finfer Michael Bannan Gottesman

Paraproteins

Lymphoplasmacytic Lymphoma

Immunophenotyping

Macroglobulinemia

Hematopathology

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Citations (30)

Monoclonal gammopathy of undetermined significance: a morphologic and immunophenotypic study of the bone marrow.

Modern Pathology (1992)

Feiner Hd Michael Bannan Elaine Marsh Chuba Jv Edith C. Espiritu

Paraproteins

Plasma cell neoplasm

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Citations (5)

Bone-marrow plasmocytosis ? An immunohistological study

Blut Zeitschrift für die gesamte Blutforschung (1986)

F Eckert L. Schmid D. Kradolfer U Schmid

10.1007/bf00320578

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Citations (15)

Monoclonal gammopathy of undetermined significance: a morphologic and immunophenotypic study of the bone marrow.

PubMed (1992)

H D Feiner M Bannan E Marsh J V Chuba E Espiritu

Paraproteins

Plasma cell neoplasm

Immunophenotyping

Plasma Cell Myeloma

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Citations (0)

Diagnostic and Prognostic Value of the MB2 Monoclonal Antibody in Paraffin-Em bedded Bone Marrow Sections of Patients with Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance

American Journal of Clinical Pathology (1990)

Marie‐Françoise Dehou Rik Schots Patrick Lacor Nicole Arras Pascal Verhavert

Routinely processed bone marrow biopsies of 59 patients with untreated multiple myeloma (MM) and of 41 patients with monoclonal gammopathies of undetermined significance (MGUS) were immunocytochemically studied with the MB2 monoclonal antibody. In 54 of 59 biopsies of patients with MM, most neoplastic plasma cells showed strong cytoplasmic positivity to MB2. In contrast, only three biopsies of patients with MGUS contained highly MB2-positive plasma cells, whereas the plasma cells in the remaining biopsies were either negative (18 of 41) or revealed a weak dot-like staining of the cytoplasm (20 of 41). Plasma cells in tonsillar tissue, gastric and duodenal mucosae, and bone marrow with reactive plasmacytosis were not stained with MB2. These findings suggest that MB2 helps to distinguish between MM and MGUS. Because the five MB2-negative patients with MM were all in stage III and had very short survival time, neoplastic plasma cell staining with MB2 could also have a prognostic significance.

Plasmacytosis

10.1093/ajcp/94.3.287

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Citations (4)

The relationship between proliferation and apoptosis in patients with monoclonal gammopathy of undetermined significance or multiple myeloma.

Haematologica (2005)

Vlastimil Ščudla M Ordeltová Jaroslav Bačovský M Vytřasová Pavel Horák

Multiple myeloma (MM) is a clonal neoplastic lymphoproliferative disease affecting terminally differentiated B cells i.e. plasma cells characterized by slow proliferation activity and different resistance to apoptosis with latent accumulation of myeloma cells in the bone marrow. This process is induced by failure of normal tissue homeostatic mechanisms. We compared plasma cell proliferation and apoptic indices in various phases of MM and in monoclonal gammophaty of untetermined significance.

Plasma Cell Myeloma

Homeostasis

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Citations (10)