Contiguous granular cell myoblastoma and squamous cell carcinoma in the oesophagus.
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Granular cell tumour of the lung is a rare benign tumour. We report a case of endobronchial granular cell tumour which occurred in a 70-yr-old male with haemoptysis. Because of the size of the tumour (greater than 8 mm) and the associated pseudoepitheliomatous hyperplasia with marked atypia, surgical resection was performed. No neoplastic relapse has been observed in nearly 4 yrs of follow-up.
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Summary A case of multiple granular cell myoblas‐tomata of the vulva in a 26‐year‐old woman is described. The pathology and possible histogenesis of the condition is discussed. Evidence in favour of a neural origin is increasing. An outline is given of the treatment and prognosis of granular cell myoblastoma.
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A case of multiple granular cell myoblastoma of the tongue is reported; the patient, a woman of 78 years, presented a tumor of the tongue, the characteristic of which differred very much from these of the typical granular cell myoblastoma. In fact, all the typical clinical features of granular cell myoblastoma, like lardaceous aspect, adhesion to the mucosa and absence of ulceration failed to be present. Moreover, this seems to be the only case, reported in the literature, with multiple lesions on the same organ.
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Two patients with multiple intrathorcic granular cell myoblastomas are described. In one case multiple tumours were present in the major airways and oesophagus. The patient presented with recurrent pulmonary infections and stridor due to airway obstruction. In the other case dysphagia caused by multiple oesophageal granular cell myoblastomas was the major symptom. Granular cell myoblastoma is a rare tumour of neurogenic origin with a characteristic histological appearance. The pattern of multiple tracheobranchial and oesophageal tumours is uncommon and forms the basis of this report.
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✓ The clinicopathological features of an unusual granular cell myoblastoma involving the fifth cranial nerve are presented. Evidence incriminating the Schwann cell as the source of the granular cell is also discussed.
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