Incorporation of ability‐based pharmacology education in an integrated medical school curriculum
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Clinical Pharmacology & Therapeutics (2003) 73 , P95–P95; doi:Keywords:
Clinical Pharmacology
Molecular Pharmacology
Clinical Pharmacology
Molecular Pharmacology
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Clinical Pharmacology
Molecular Pharmacology
Safety pharmacology
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Clinical Pharmacology
Molecular Pharmacology
Disposition
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Translational Pharmacology is a newly evolved branch as an extension of clinical pharmacology. Translational Pharmacology aims to move the results of the molecular pharmacological research to the patient level, which is focussed on developing the new drug that correlates with the patient needs. The basic objective is to study the changing trends from experimental to clinical pharmacology. It also helps to gather data from the preclinical studies, so as to have accurate and effective dosing in the critical clinical trials. Thus, we can conclude that Translational Pharmacology tries to bridge the gap between the basic molecular research studies in pharmacology to the clinical trials. This also reduces the time and economic burden on research. Thus, it helps in translating the knowledge from the basic animal studies to the bedside patient studies.
Clinical Pharmacology
Translational Research
Molecular Pharmacology
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Translational Medicine
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Clinical Pharmacology
Molecular Pharmacology
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The title of this article may raise a smile from colleagues in the field of basic pharmacology. To them, pharmacology has always been about molecular interactions, and this title may simply confirm a suspicion that clinical pharmacology is mainly about semi-quantitative observations that have only a limited foundation in hard science. They are partly right, at least regarding a communication problem. In a discussion about systems biology, an exasperated engineer once remarked that biologists and physicians do not even use the same routine software packages that engineers do. Similarly, a basic pharmacologist might note that, whereas he measures drug concentrations in micromoles, the clinical pharmacologist uses micrograms per milliliters. Nevertheless, as clinical pharmacologists seek to make more quantitative observations at the molecular level in living humans, our colleagues in basic pharmacology are delving into cellular signal transduction systems governed by complex protein-protein interactions and regulated by positive and negative feedback loops. In seeking to understand these systems, they face problems that are similar to the challenge of measurement in intact humans.
Clinical Pharmacology
Molecular Pharmacology
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Clinical Pharmacology
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Pharmacometrics and systems pharmacology are emerging as principal quantitative sciences within drug development and experimental therapeutics. In recognition of the importance of pharmacometrics and systems pharmacology to the discipline of clinical pharmacology, the American Society for Clinical Pharmacology and Therapeutics (ASCPT), in collaboration with Nature Publishing Group and Clinical Pharmacology & Therapeutics, has established CPT: Pharmacometrics & Systems Pharmacology to inform the field and shape the discipline.
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Clinical pharmacology is an essential discipline in the development of new medicines, but the closely specified requirements of pharmaceutical industry protocols and regulatory reviewers have limited the opportunities for curiosity-driven research. Realization is growing that there is so much that is not known about the mechanisms underlying human disease and the actions of medicines on them that research of a more exploratory kind, namely, investigative clinical pharmacology, is a priority.
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International Journal Of Pharmacology And Therapeutics well known high impact journal of Earth Journals publisher. It is open Access journals devoted to pharmacology disciplines in science . Journal covers the pulmonary, gastrointestinal and urogenital pharmacology, endocrine, neuro-pharmacology , analgesia, cardiovascular pharmacology, pharmacology, immune-pharmacology and inflammation and molecular cellular pharmacology and behavioral pharmacology.
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