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    Sickle beta-thalassemia presenting as orbital compression syndrome
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    Background: The World Health Organization (WHO) estimates that about 2 billion individuals or about 40% of the world's population suffer from anemia. The population groups with the highest prevalence of anemia are: pregnant women and the elderly (about 50%), infants and children 1 to 2 years (48%), school children (40%), non-pregnant women (35%), and preschoolers (25%).Methods: The study was conducted at MediCiti Institute of Medical Sciences. 1007 children were screened clinically and their blood samples collected and analyzed by hemocue instrument. A complete physical examination was done for all these children.Results: The maximum number of subjects belongs to the nine year old category. Boys constituted 46% of the study population while girls constituted 54% of the study population. Anemia is more prevalent in female subjects than males. In the present study, clinical pallor was present in 16.48% of the subjects. In specific, conjunctival pallor was noted in 9.43%, generalized pallor of skin noted in 4.96% and palmar crease pallor was noted in 1.88% of subjects. The sensitivity and specificity of clinical pallor in diagnosing anemia is 94.02% and 93.71% respectively. The sensitivity and specificity of palmar pallor in diagnosing severe anemia is 100% and 98.21% respectively.Conclusions: The clinical finding of pallor in a child is a reliable indicator of anemia. The presence of clinical pallor in any of the body sites (conjunctival pallor, skin pallor, palmar pallor) is a reliable indicator of anemia. The presence of palmar crease pallor is a good indicator of severe anemia in children. By effective implementation of mid-day meal scheme, the incidence of anemia could be brought down effectively.
    Pallor
    Population study
    Clinically significant chemosis occasionally complicates lower eyelid blepharoplasty. In this report, the etiologic components of postblepharoplasty chemosis are discussed. The time course and duration of chemosis vary according to the underlying cause. Early, late, and prolonged chemosis are managed with different strategies. Diagnostic and therapeutic algorithms for chemosis assessment and management are presented.
    Chemosis
    Citations (42)
    To identify a marker associated with poor outcome in severe malaria that requires no technology, the relationship between the presence of pallor and mortality was reviewed retrospectively in 291 Zambian children with cerebral malaria. The mean (S.D.) haemoglobin concentration among the 222 children assessed as having pallor on admission was significantly lower than that among the 69 children not considered to have pallor [6.0 (1.9) v. 9.2 (1.6) g/dl; P < 0.0005]. Thirty-nine (17.6%) of the children presenting with pallor died, compared with only five (7.2%) of those without pallor (P = 0.036). The adjusted odds of death in children with pallor on admission was 2.8 times higher than that in children without pallor (95% confidence interval = 1.03-7.7; P = 0.044). The clinical observation of pallor may therefore identify children with low haemoglobin concentrations and a high risk of mortality. Whether mothers and village health workers can be taught to recognize pallor in a child with malaria and then to seek early medical attention will need to be determined in further studies.
    Pallor
    Cerebral Malaria
    Citations (24)
    OBJECTIVE To explore the relationship between eyeball structure and visual acuity in high myopia. METHODS Totally, 152 people (283 eyeballs) with different levels of myopia were tested for visual acuity, axial length, and fundus. All cases were classified according to diopter, axial length, and fundus. The relationships between diopter, axial length, fundus and visual acuity were studied. The mathematical models were established for visual acuity and eyeball structure markers. RESULTS The visual acuity showed a moderate correlation with fundus class, comus, axial length and diopter ([r] > 0.4, P < 0.000 1). The visual acuity in people with the axial length longer than 30.00 mm, diopter above -20.00 D and fundus in 4th class were mostly below 0.5. The mathematical models were established by visual acuity and eyeball structure markers. CONCLUSION The visual acuity should decline with axial length extension, diopter deepening and pathological deterioration of fundus. To detect the structure changes by combining different kinds of objective methods can help to assess and to judge the vision in high myopia.
    Fundus (uterus)
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    Persistent conjunctival chemosis in patients who have undergone cosmetic eyelid surgery is an uncommon but aesthetically undesirable and potentially debilitating postoperative complication. We attempted to determine if a regional conjunctivoplasty can effectively reduce signs and symptoms of chronic postoperative chemosis in these patients. Three patients with iatrogenic chemosis resistant to conservative management (ie, lubrication, pressure patching, and steroid drops) and persisting for more than 6 months after the initial surgery were included. A limbal peritomy followed by subconjunctival and sub-Tenon's fascia dissection was performed in regions of clinically detectable chemosis. Patients were followed postoperatively for 3 to 9 months to assess clinical response. All patients demonstrated significant objective improvement in clinically observable chemosis as well as symptoms related to ocular surface dryness.
    Chemosis
    Ocular surgery
    Citations (20)
    Critically ill patients cannot complain about eye problems. Eyecare is often overlooked in the intensive care units (ICUs) because treatment is mainly focused on failures of organ which results in eye complications which are preventable. Therefore, we report a case of a patient admitted to the ICU who developed unusual bilateral hemorrhagic chemosis. Although, chemosis has been encountered often in the ICU, hemorrhagic chemosis without prior direct trauma is unusual.
    Chemosis
    Citations (0)
    To identify a marker associated with poor outcome in severe malaria that requires no technology, the relationship between the presence of pallor and mortality was reviewed retrospectively in 291 Zambian children with cerebral malaria. The mean (s.d.) haemoglobin concentration among the 222 children assessed as having pallor on admission was significantly lower than that among the 69 children not considered to have pallor [6.0 (1.9) v. 9.2 (1.6) g/dl; P< 0.0005], Thirty-nine (17.6%) of the children presenting with pallor died, compared with only five (7.2%) of those without pallor (P = 0.036). The adjusted odds of death in children with pallor on admission was 2.8 times higher than that in children without pallor (95% confidence interval = 1.03–7.7; P= 0.044). The clinical observation of pallor may therefore identify children with low haemoglobin concentrations and a high risk of mortality. Whether mothers and village health workers can be taught to recognize pallor in a child with malaria and then to seek early medical attention will need to be determined in further studies.
    Pallor
    Cerebral Malaria
    Chemosis is a common occurrence after orbital reconstruction surgery by the transconjunctival approach. The authors propose an early tarsorrhaphy approach for treating severe conjunctival chemosis following orbital fracture repair.All severe conjunctival chemosis patients following orbital fracture repair were divided into 2 groups: tarsorrhaphy performed immediately when the eyelids could not close completely due to prominent conjunctival edema (early tarsorrhaphy, n = 10); and tarsorrhaphy performed 3 days after the appearance of severe chemosis (delayed tarsorrhaphy, n = 10). Once the conjunctiva subsided, the sutures were immediately removed. The duration of conjunctival edema was recorded.The average time to resolution of severe chemosis was significantly shorter in the early versus delayed tarsorrhaphy group (3.5 ± 0.5 versus 7.2 ± 1.73 days, P < 0.05). No recurrence of conjunctival edema occurred in any patient 4 months postoperatively.Early temporary tarsorrhaphy is a fast and effective method for the treatment of conjunctival chemosis following orbital fracture surgery. The sooner eyelid suturing is performed, the faster conjunctival chemosis will subside.
    Chemosis
    Orbital Fracture