The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome
Ming Yang BiJonathan L. CurryAngela M. ChristianoMaria HordinskyDavid A. NorrisVera H. PriceMadeleine Duvic
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Alopecia areata is a prevalent autoimmune skin disease resulting in the loss of hair on the scalp and elsewhere on the body. It usually starts with one or more small, round, smooth patches on the scalp and can progress to total scalp hair loss (alopecia totalis) or complete body hair loss (alopecia universalis). The scalp is the most commonly affected area, but the beard or any hair-bearing site can be affected alone or together with the scalp. Alopecia areata occurs in males and females of all ages, but onset often occurs in childhood. Over people 147 million worldwide have, had or will develop alopecia areata at some point in their lives. According to Ayurveda, pitta dosha is the primary cause of hair loss. Pitta dosha could be reversed through diet and lifestyle modifications. Ayurvedic medicine for hair loss contains herbs that can arrest hair fall and improve hair growth.
Alopecia universalis
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Alopecia areata (AA) is a disease involving non-scarring hair loss is a common and complex T-cell-mediated inflammatory disorder. Alopecia areata, also known as spot baldness. It brings about a couple of uncovered spots on the scalp, each about the size of a coin. In such cases hair on the scalp or all body hair is and loss can be permanent. Alopecia areata affects males and females. It is an acquired skin disease that can affect all hair-bearing skin. Alopecia areata has a reported incidence of 0.1-0.2%.
The disease can start at any age, but the peak incidence is 20years to 50 years of age. Both the sexes are equally affected; It often first appears during childhood and can be different for everyone who has it. and there is no racial variation reported Clinically, alopecia may present as a single well demarcated patch of hair loss, multiple patches, or extensive hair loss in the form of total loss of scalp hair or loss of entire scalp and body hair.
From resources knowing that alopecia areata is happened by an abnormality in the immune system that damages hair follicles. This particular abnormality leads to autoimmunity, a misguided immune system that tends to attack its own body. So a a result, the immune system attacks particular tissues of the body. In alopecia areata, without any reasons, the body's own immune system attacks the hair follicles and disrupts normal hair formation. Treatment may contains any conditions and includes topical scalp medication. Sometimes it is related with other autoimmune conditions such as: thyroid disease, vitiligo, lupus, rheumatoid arthritis, and ulcerative colitis. The characteristic finding of alopecia areata is one or more well-circumscribed areas of otherwise normal, hairless skin in hair-bearing areas. Occasionally, it may be necessary to biopsy the scalp to confirm the diagnosis. Other findings that may be helpful are the appearance of short hairs that presumably represent fractured hairs, short thin hairs, and gray hair growing in a bald area. Other causes of hair loss are generally excluded from the consideration by history and clinical evaluation.
Androgenetic alopecia is a form of hair loss in both men and women. In men, this condition is also known as male-pattern baldness. Hair is lost in a well-defined pattern, beginning above both temples. Over time, the hairline recedes to form a characteristic M shape. Hair also thins at the near top of the head, often progressing to partial or complete baldness.
The pattern of women baldness differs from male-pattern baldness. In women, the hair becomes thinner all over the head, and the hairline does not recover. Androgenetic alopecia in women rarely leads to total baldness. It is well known that prostaglandin–F is Hair follicle stimulant, and it is used as anti-glaucoma drugs and of the side effect is to have longer eye lashes from here come the idea to mix those kinds of eye drops with P.R.P treatment. PRP is a platelet-rich plasma therapy for hair loss. It is a three-step medical treatment in which a person’s blood is drawn, processed, and then injected into the scalp. PRP is an effective hair loss treatment.
Most PRP therapy requires three treatments 4–6 weeks apart. So we received this 18 years lady with history of 8 years of alopecia universalis and she tried all types of treatment without any response. Now after mixing P.R.P with eye drops for 6 sessions we got this amazing result that we can prove with pictures and for the safety of drug with no systemic side effect except some abdominal cramps. We start to use this treatment as well with androgenic alopecia and we received great result superior to P.R.P alone
Alopecia universalis
Body hair
Hair disease
Cabello
Vellus hair
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Alopecia areata is a condition that causes hair to fall out in small patches, which can be unnoticeable. Often it results in a few bald spots on the scalp, each about the size of a coin. The condition develops when the immune system attacks the hair follicles, resulting in hair loss. Alopecia areata also known as spot baldness. In a few cases, all the hair on the scalp or all body hair is lost and loss can be permanent. The condition can result in total hair loss, called alopecia universalis, and it can prevent hair from growing back. When hair does grow back, it’s possible for the hair to fall out again. The extent of hair loss and regrowth varies from person to person. The main cause is that it is an autoimmune condition in which the body attacks its own anagen hair follicles and suppresses or stops hair growth.
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Alopecia universalis
Vellus hair
Hair disease
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Male-pattern baldness
Pubic hair
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Alopecia universalis
Body hair
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Alopecia universalis
Hair disease
Male-pattern baldness
Body hair
Cabello
Scarring alopecia
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Background: Hair is one of the defining characteristics of mammals. Hair loss may not harm physically that much but it might lead to psychological impact and may cause depression. Alopecia areata (AA) is a condition resulting in localized, nonscarring hair loss. Patches are more common on the scalp without any scaling and inflammation. In Ayurveda texts, a similar condition is mentioned in Kshudrarogas known as Indralupta. The aim of this study was to assess the efficacy of Jalaukavacharana in Alopecia areata. Materials and Methods: It is a single case study of a 22-year-old female patient with a complaint of asymptomatic loss of hair at a single site over the scalp for 5 months. This case of Alopecia areata (Indralupta) was successfully treated with 12 sittings of Jalaukavacharana (leech therapy) for four and a half months and 3 months Ayurveda medication. Result: The patch was immensely filled with lustrous black hairs at the end of the follow-up period. Conclusion: Hence, it can be concluded that Ayurveda provides a promising result in the patient of Indralupta through Jaloukavacharana and Shamana Aushadh. It can be a choice of treatment, keeping in mind its cost-effectiveness and successful management as compared to conservative treatment.
Depression
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Alopecia universalis
Body hair
Cabello
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Body hair
Hair disease
Vellus hair
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Alopecia areata (AA) is a common, immune-mediated, nonscarring hair loss disorder. It typically presents with sharply demarcated round patches of hair loss and can be found in any age. Severe hair loss forms include alopecia totalis and alopecia universalis. AA may significantly affect a patient's quality of life.1 Here, we report a case of AA presenting a linear form of alopecia.
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Purpose: Alopecia aerata is one among the most prevalent human autoimmune diseases, leading to disfiguring hair loss by the collapse of immune privilege in the hair follicle and subsequent autoimmune attack. Generally, hair loss in patches signifies alopecia areata. It typically presents a gradual or sudden loss of hair in head, eyebrows, eyelashes, nasal, ear and other areas of the body causing patches to appear. Alopecia areata or hair loss occurs in one in 1,000 people. Autoimmune-associated alopecia areata has no age boundaries and can affect even children, men and women equally. If left untreated, or if the disease does not respond to treatment, complete baldness can result in the affected area. The two major forms of Alopecia are scarring and non scarring. Highlighting the significance, a study was carried out to evaluate the therapeutic efficacy of Ayurvedic formulations in patients with Alopecia Areata. Method: Fifteen alopecia areata patients of either sex with varying degrees of hair loss were randomly selected for the clinical trial and were treated with Indralupta Bhasma, Malathyadi Tailam and Guduchi tablet for a period of 3-5 months. Subsequently, most of them were observed bi monthly up to a 5 months period. Result: Findings revealed that 8 of the15 patients with patchy progressive hair loss stabilised and showed no additional hair loss. After 3-5 months of treatment hair growth in these patients were partial or full. Of the other 7 patients with stable patchy total hair loss, four had some limited growth, two patients displayed complete growth of eyebrows and eyelashes, but had poor hair growth on scalp while one patient did not show any response. Conclusion: The study vividly indicated the efficacy of Ayurvedic formulations in patients with Alopecia Areata. The trial medicines too proved to be effective minimizing the patchy hair loss.
Alopecia universalis
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Hair transplantation
Hair disease
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