Increased Endothelial Apoptotic Cell Density in Human Diabetic Erectile Tissue—Comparison with Clinical Data
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Erectile tissue
Objective To study the clinical characteristics of erectile dysfunction(ED). Methods 140 erectile dysfunction patients were evaluated by the erectile function(EF)domain of the international index of erectile function(IIEF). Results There were 22 cases of psychologic ED ,56 cases of organic ED and 62 mixed ED cases.61 patients were under 50 years old ,whose average ED duration was 51.4 months,and EF score 12.1±4.5,only 18 cases had risk factors.Whereas there were 79 patients over 50 years,their average ED duration was 76.3 months,and their average EF score 9.1±4.1,48 of them had risk factors.Statistic analysis showed there were significant difference in ED duration、IIEF score and risk factors between the two groups( P 0.01). Conclusions The results indicated that patients over 50 years had more risk factors,and they intended to get worse erectile dysfunction.The EF domain is a simple and practical means to evaluating erectile dysfunction.
Statistic
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Doxazosin
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A total of 76 patients with chronic abacterial prostatitis (CAP) in combination with erectile dysfunction were divided into two groups. Clinical symptoms of CAP and severity of erectile dysfunction were the same in both groups. Patients of the study group (n = 36) received pathogenetic treatment (vitaprost plus physiotherapy) and impase. The control group (n = 40) received vitaprost and physiotherapy. The results of the treatment showed that impase addition to combined treatment of CAP patients with erectile dysfunction significantly improves erectile function: 80.6% patients given impase raised their score by International Index of Erectile Function Scale to normal (26 points and higher). Impase efficacy increased with prolongation of the treatment from 4 to 12 weeks.
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The aim of our study was to investigate the effect of antihypertensive treatment on erectile function in patients with essential hypertension. From our hypertension outpatient clinic, 358 consecutive young and middle-aged men (31–65 years old, 49.1±5.2 years) with essential hypertension filled a questionnaire regarding erectile function (International Index for Erectile Function). Antihypertensive therapy significantly affected the erectile function of our patients, with patients on combination therapy exhibiting the higher prevalence of erectile dysfunction. Older antihypertensive drugs exhibit worse profile on erectile function than newer drugs, suggesting that this may be another parameter for the proper choice of antihypertensive drug.
Antihypertensive drug
Pharmacotherapy
Essential hypertension
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A cross-sectional study was carried out with 288 male blood donors, aged between 40 and 60 years old, with the aim of comparing the prevalence of erectile dysfunction (ED) as defined by the International Index of Erectile Function (IIEF) and that resulting from the simple questioning of the presence of ED. Socio-demographic, clinical, and behavioral factors that are associated with the presence of ED were considered. Erectile dysfunction prevalence in the IIEF was 31.9%, while self-reported ED prevalence was 3.1%. The factors associated to ED, as reported by the IIEF were: professional inactivity, suspected depression and/or anxiety, reduced sexual desired, and self-reported ED.
Depression
Cross-sectional study
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Objectives: To investigate the age-related differences of erectile function and erectile hardness in erectile dysfunction( ED) patients. Method: The data were retrieved in a baseline database on an ED management study which was performed in 46 urological clinics in China. The patients were stratified on the basis of every 10 years( yrs) old. International Index of Erectile Function( IIEF-EF) and Erection Hardness Score were adopted as the scale to evaluate erectile functions and the Erection Hardness Score( EHS). Statistical analysis were then done to make comparisons among different age groups. Results: The study included 4241 ED patients with an age range from 20 to 84 yrs( average 42. 3 ± 12. 3 yrs); 55. 6% patients were between 31 to 50 yrs old. For patients over 30 yrs old,with the increase of age,both scores of IIEF-EF and EHS tended to decrease. Decrease of erectile function and erectile hardness scores were statistically significant between the patients aged over and below 50 yrs, and the conditions were even worse in the patients over 60 yrs. Conclusion: This study suggested that for men below 50 yrs old,prevention and treatment of ED were essential; while for those over 50 yrs old,the treatment of ED and the prevention of its comorbidities were highly recommended.
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