Burden of isolation for multidrug-resistant organisms in a tertiary public hospital in Southern Brazil

Infection with carbapenem-resistant Enterobacteriaceae (CRE) or carbapenemase-producing Enterobacteriaceae is emerging as an important challenge in health-care settings. Currently, carbapenem-resistant Klebsiella pneumoniae (CRKP) is the species of CRE most commonly encountered in the United States. CRKP is resistant to almost all available antimicrobial agents, and infections with CRKP have been associated with high rates of morbidity and mortality, particularly among persons with prolonged hospitalization and those who are critically ill and exposed to invasive devices (e.g., ventilators or central venous catheters). This report provides updated recommendations from CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC) for the control of CRE or carbapenemase-producing Enterobacteriaceae in acute care (inpatient) facilities. For all acute care facilities, CDC and HICPAC recommend an aggressive infection control strategy, including managing all patients with CRE using contact precautions and implementing Clinical and Laboratory Standards Institute (CLSI) guidelines for detection of carbapenemase production. In areas where CRE are not endemic, acute care facilities should 1) review microbiology records for the preceding 6-12 months to determine whether CRE have been recovered at the facility, 2) if the review finds previously unrecognized CRE, perform a point prevalence culture survey in high-risk units to look for other cases of CRE, and 3) perform active surveillance cultures of patients with epidemiologic links to persons from whom CRE have been recovered. In areas where CRE are endemic, an increased likelihood exists for imporation of CRE, and facilities should consider additional strategies to reduce rates of CRE. Acute care facilities should review these recommendations and implement appropriate strategies to limit the spread of these pathogens.

Carbapenem-resistant enterobacteriaceae

Acute care

Carbapenem

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Citations (217)

Hospital-acquired Infection Control and Prevention for SARS: Effects of Disinfection and Isolation

Chinese Journal of Nosoconmiology (2004)

Xitao Ma

OBJECTIVE To evaluate the effects of disinfection and isolation measures on hospital-acquired infection and control and prevention for SARS. METHODS Based on the problems of hospital-acquired infection control and prevention for SARS in Henan Province, the prevention measures including intensive training, standardized precautions, and management were strengthened in all hospitals in Henan. RESULTS There were no any infection for health care workers and no spreading of SARS cases in Henan, no exporting cases from Henan, and no any death cases. CONCLUSIONS The hospital-acquired infection of SARS can be prevented and controlled by means of the effective measures such as disinfection and isolation.

Isolation

Hospital-acquired infection

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Citations (1)

Isolation Rooms for Tuberculosis Control

Infection Control and Hospital Epidemiology (1993)

Mark Nicas Joan E. Sprinson Sarah Royce Robert J. Harrison Janet M. Macher

Isolation

Patient isolation

Tuberculosis control

10.1086/646653

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Citations (4)

Isolation needs and control of infection in NZ hospitals.

PubMed (1981)

Lang Wr

The purpose of this paper is to discuss infections in New Zealand hospitals under two headings: 1. Isolation needs. 2. Control of infection as it pertains to prophylaxis. An assessment of modern needs in terms of numbers of isolation beds is made on the basis of present-day infections. Brief reference is made to the epidemiology of hospital infections and to the principles of isolation according to categories of infection -- the Card System -- and to specification of the facilities required. The importance of a Control of Infection Nurse is emphasised and suggested members of a Control of Infection committee are enumerated. The proposed methods for preventing and dealing with infections apply particularly to base hospitals. It is hoped however that the principles enunciated are sufficiently obvious that they can be readily adapted to smaller community hospitals. It is concluded that all New Zealand hospitals should have a formal control of infections system instituted.

Isolation

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Citations (0)

Isolation for the Control of Staphylococcal Infection in Surgical Wards

BMJ (1962)

R. E. O. Williams W. C. Noble M. P. Jevons O. M. Lidwell R. A. Shooter

Isolation

Patient isolation

Cross infection

10.1136/bmj.2.5300.275

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