ChemInform Abstract: A Convenient Catalytic Asymmetric Conjugate Addition Reaction to Enones Using Alkylzirconium Reagents.
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Abstract Alkylmetal species generated in situ from alkenes and the Schwartz reagent undergo enantioselective 1,4‐conjugate addition to enones in the presence of a chiral copper complex as catalyst.Keywords:
Conjugate
Addition reaction
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Abstract Review: 284 refs.
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Conjugate
Camphor
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ALUMINUM HYDRIDE
Lithium aluminium hydride
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Abstract The tripeptide D‐Pro‐Pro‐Glu‐NH 2 is highly efficient for the title reactions.
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This chapter contains sections titled: Introduction Additions to Aldehydes and Ketones Additions to Imines and Iminium Ions Additions to Carboxylic Acids and Their Derivatives Conjugate Addition to α,β-Unsaturated Carbonyl Compounds Synthesis of Heterocycles References
Iminium
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Carbonyl group
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Abstract The cyclohexenecarboxylate (I) reacts with the butylcuprates (II) to produce the 2‐butylcyclohexanecarboxylate (III) whereas treatment of (I) with (V) or (VI) yields the cyclohexyl butyl ketone (IV) as the main product.
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Abstract The methyleneimidazolidines (I) react with the electron‐deficient olefins (II) to give the adducts (III) which are hydrolyzed and decarboxylated to form the imidazolidines (IV).
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ChemInform Abstract: Conjugate Addition Reactions of α‐Aminoalkylcuprates with α,β‐Enones and Enals.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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This chapter contains sections titled: Introduction Conjugate Reaction of α,β-Unsaturated Ketones, Amides, and Nitriles Conjugate Addition of Nitroalkenes Conjugate Addition of Vinyl Sulfones and Vinyl Phosphates Cyclopropanation and Other Related Reactions Conclusions References
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Nucleophilic Addition
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Abstract The unsaturated lactones (I) and (X) and the unsaturated lactam (XIII) undergo conjugate addition reaction with the phenyldimethylsilylcuprate (II) or the Grignard reagent (VII) to give the trans‐products (III), (VIIIa), (XI), and (XIV).
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