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    Fatal Outcome after Embolotherapy for Hepatic Arteriovenous Malformations of the Liver in Two Patients with Hereditary Hemorrhagic Telangiectasia
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    Hereditary hemorrhagic telangiectasia(HHT)is an autosomal dominant vascular disease, characterized by recurrent nosebleeds(epist axis), multiple telangiectases and arteriovenous malformations(AVMs). In this paper, the comprehensive treatment of the latest research progress at home and abroad, provide a new treatment strategy for Hereditary hemorrhagic telangiectasia expansion strategy. Key words: Telangiectasia, Hereditary Hemorrhagic; Vascular Endothelial Growth Factors
    Telangiectases
    ACVRL1
    Introduction: Hereditary hemorrhagic telangiectasia (HHT) or Rendu–Osler–Weber disease is an autosomal dominant disorder characterized by epistaxis, mucocutaneous telangiectases and visceral arteriovenous malformations. Cutaneous telangiectases are the most obvious sign of this disorder and are not a merely cosmetic problem owing to their risk for bleeding, which may constitute an authentic matter of concern to these patients. Methods: Three patients with type‐II HHT disease who presented cutaneous and labial lesions were treated with an intense pulsed light (IPL) system associated with a long‐pulsed Nd:YAG laser (Photoderm‐Vasculight, Lumenis). Labial lesions were treated with the IPL system and cutaneous lesions were treated with the IPL system and the long‐pulsed Nd:YAG laser. All treatments were accomplished on an outpatient basis, without anesthesia. Results: All three patients experienced a reduction in the frequency and severity of bleeding episodes and a great cosmetic improvement, with total lesion clearance. Side effects, such as purpura, hypopigmentation, hyperpigmentation or textural changes, were not observed. Recurrences were not detected after a maximum period of 24 months of follow‐up. Conclusion: The combination of an IPL system and a long‐pulsed Nd:YAG laser is efficient and safe for the treatment of cutaneous and labial telangiectases in patients with HHT disease and constitutes an important tool in improving their quality of life.
    Telangiectases
    Intense pulsed light
    Mucocutaneous zone
    Hypopigmentation
    Inframammary fold
    Hypertrichosis
    Citations (31)
    Hereditary hemorrhagic telangiectasia, also known as Rendu-Osler-Weber syndrome, is a familial disease in which telangiectases occur in the skin, mucosal surfaces, and solid organs1,2. Small telangiectases are a mild cosmetic problem, but larger lesions can be a source of chronic blood loss, systemic emboli, hypoxemia, hepatic dysfunction, and high-output cardiac failure. The treatment of troublesome telangiectasia in patients with this disease has always been difficult, because bleeding sites may be many and scattered. Treatment often requires multiple blood transfusions, large doses of iron, and various invasive procedures in order to make the diagnosis, staunch bleeding, or prevent recurrent . . .
    Telangiectases
    Rare disease
    Hereditary hemorrhagic telangiectasia, also known as Osler-Weber-Rendu disease, is an autosomal dominant disorder involving vascular abnormalities of various organs. Telangiectases are frequently observed, predominantly on the nasal and oral mucosa. We present a case a of 53-year-old man with the tonge hemorrhagic telangiectases and epistaxis. Selective catheterization and embolization of the right lingual artery led to size redution and no bleeding from tongue telangiectases.
    Telangiectases
    Oral mucosa
    Hereditary hemorrhagic telangiectasia (HHT) is an autosomal-dominant disorder. The disease has been formally characterized with epistaxis, cutaneous and mucosal telangiectases, a first-degree relative with HHT, and visceral lesions such as arteriovenous malformations (AVMs). Hereditary hemorrhagic telangiectasia has been underreported for many years. Wider recognition of this disorder in recent years has prompted researchers and physicians to recognize milder cases and focus on earlier treatment. This article highlights different treatments used to control epistaxis and screen for other complications associated with HHT.
    Telangiectases
    Treatment modality
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    To the Editor: Hereditary hemorrhagic telangiectasia is an autosomal dominant disease characterized by epistaxis, cutaneous telangiectases, and visceral arteriovenous malformations.1 Aminocaproic a...
    Telangiectases
    Hemorrhagic diathesis
    Inherited disease
    Citations (72)