ChemInform Abstract: Stereoselective Oxidation of 2‐(4‐Chlorophenyl)‐4a,5‐dihydro‐2H‐(1) benzothiopyrano(4,3‐c)pyridazin‐3(4H)‐one to Sulfoxide.
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Sulfoxide
Abstract The cycloanellation reaction is first studied for some model compounds and thereupon used as starting step in the synthesis of the title compound (VII).
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Allyltitanocene complexes can be generated by reacting pentafulvenes with DIBAL-H and Cp2TiCl2. Their coupling with aldehydes affords homoallylic alcohols in a highly regio- and stereoselective manner. The potential of this method for the stereoselective synthesis of cyclopentane derivatives is illustrated.
Cyclopentanes
Surface Modification
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Synthon
Conjugate
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Moiety
Succinimides
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Tandem
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A remarkably stereoselective reduction of a γ-hydroxyketone with two equiv. of lithium triethylborohydride has been observed and this effect has been suggested to originate from 'chelation control'; the reaction has been utilised in a short stereoselective synthesis of ancistrofuran.
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ALUMINUM HYDRIDE
Diastereomer
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Abstract In the presence of a catalytic amount of several trityl salts, 2,3,5-tri-O-benzyl-d-ribofuranose smoothly reacted with alcohols to give various β-ribofuranosides in high yields with high stereoselectivity while reversed stereoselectivity was observed in the coexistence of lithium perchlolate.
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