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    Evidence for the propagation of the virus of serum hepatitis in the chick embryo
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    Neonatal jaundice is the most common problems in clinic and International health. Neonatal jaundice trends to rise in the hospital. There have many complications and causes of neonatal jaundice. for developing neonatal jaundice. Neonatal jaundice can prevent and curative. Objective: Aim to evaluated incidence of neonatal jaundice and determined causes of neonatal jaundice in Phukieochalermprakiat hospital Material and methods: Neonate with a diagnosis of neonatal jaundice in Phukieochalermprakiat hospital between June 1st, 2017 - May 31th, 2020 were retro descriptive study reviewed. Demographic data, age at onset, blood microbilirubin, cause of neonatal hyperbilirubinemia and re-admission for phototherapy were reviewed and recorded into a standard case record form. Descriptive statistics were reported as frequency and percentage for categorical variables. Results: A total of 3,480 live births at Phukieochalermprakiat hospital. The prevalence of neonatal jaundice was 546 (15.6%). Cause of neonatal jaundice, 55.5% were Breast feeding jaundice, 15.7% were G6PD deficiency, 14.8% were ABO incompatibility, 7.8% were Breast milk jaundice, 3.1% were Jaundice of prematurity and 2.1% for neonatal sepsis. All neonatal jaundice get phototherapy and no one get blood exchange. Forty-two cases were re-admitted due to neonatal jaundice and needed phototherapy. Conclusion: The incidence of neonatal jaundice was common found at Phukieochalermprakiat hospital. The most common cause of neonatal jaundice was breast feeding jaundice, G6PD deficiency and ABO incompatibility.
    Neonatal Sepsis
    Exchange transfusion
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    Objective: Correct infant jaundice effectively early in order to prevent the brain disease damaged by jaundice Methods: 78 cases of infant jaundice were randomly divided into two groups The control group people are cured normally and the experiment group are cured by potenlini Results: The jaundice declining of the experiment group is obviously, which accounts for 5017±2526 μmol/L every day There is a great significance between the control and experiment groups Conclusion: Potenilin can be used to cure jaundice and which can reduce the infant jaundice value
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    Results The results of this study demonstrate that hepatitis E virus (HEV-RNA) infection to be rare (6.25%) in HBVDNA positive cases. Surface antigen (HBsAg) for hepatitis B virus was positive in 18 cases (45%) and IgM Anti HEV was positive in 16 cases (40%). Hepatitis B virus infections, as the predominant causes of liver diseases, HBV-DNA was detected in 32 cases out of 40 cases and HEV-RNA was detected in 2 cases out of 32 HBV-DNA positive cases respectively. Co-infection of both HBV and HEV were reported in acute and chronic liver diseases in more than 18% cases by ELISA and 6.25% cases by real time PCR.
    Medical microbiology
    Hepatitis E Virus
    Infectivity
    Acute hepatitis
    Hepatitis E
    This study aimed to determine the gaps of knowledge and practices of care of neonatal jaundice among Malaysian mothers. It was a cross sectional study of 400 mothers who attended the obstetric clinics or were admitted to the obstetric wards of a general hospital. They were surveyed with a structured set of questionnaire. The results showed that a majority (93.8%) of them knew about neonatal jaundice, and 71.7% knew that jaundice lasting more than 2 weeks was abnormal. However, only 34.3% of them were aware that jaundice appearing during the first 36 hours of life was abnormal. Less than 20% knew about glucose-6-phosphate dehydrogenase deficiency and that fetal-maternal blood group differences could cause jaundice. Although 71.7% and 69.7%, respectively, of the mothers knew that severe jaundice could cause death and brain damage, only 38.4% of them were aware that severe jaundice could result in hearing impairment. A very low proportion (27.1%) of them was aware that putting jaundiced infants under the direct sun could result in dehydration and worsening of jaundice. Out of a maximum score of 15, the mean maternal knowledge score was 7.4 (95% confidence intervals: 7.1, 7.7). Majority (83.1%) of the multiparous mothers with a past history of having children developing neonatal jaundice (n = 154) practiced placing their infants under the direct sun. This study revealed that there was a wide knowledge gap among Malaysian mothers on care of neonatal jaundice. Placing infants under the direct sun was still a common practice.
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    Objective To investigate the influence of neonatal jaundice on cochiea and clinical significance of hearing screening in aundiced neonates by otoacoustic emission(OAE). Methods Two hundred and twenty-three cases of neonatal jaundice were divided into three groups by serum bilirublin between February 2003 to May 2007, 44 cases in the mild jaundice group,92 cases in the intermediate jaundice group and 87 cases in the severe jaundice group.The first OAE were given when the patients were taken to hostipal,and the second test before leaving.The patients who didn't pass the test were tested once again with these ocedures after 4 weeks.Those who failed to pass the third hearing screening were followed up until 6 months old by OAE,and coustic brain-stem response(ABR)was used to monitor the hearing. Results The first time: 81.8% passed in the mild jaundice group, 65.2% passed in the intermediate jaundice group, 49.4% passed in the severe jaundice group,and there was statistical significance between the mild jaundice group and the intermediate jaundice group, the intermediate jaundice group and the severe jaundice group(P<0.05). The second time: 100.0% passed in the mild jaundice group, 88.0% passed in the intermediate jaundice group,74.7% passed in the severe jaundice group.3 months old: 100.0% passed in the intermediate jaundice group,88.5% passedin the severe jaundice group.The passed didn't reach 100.0% in the severe jaundice group in their 6 months old,and those failured to pass were determined with hearing loss. Conclusions Neonatal jaundice can cause hearing loss of neonates and the presence of OAE is closely related to its degree.The influence of severe jaundice and severe jaundice on cochiear is reversible.The OAE test has been found to be practical and quick enough to be performed in jaundiced neonates. Key words: Neonatal jaundice;  Otoacoustic emission
    The Diagnosis and Treatment of Jaundice According to the Morbid Pulse in the Chapter 15 of Synopsis of Golden Chamber sets forth the classification, symptom, method of treatment, formula, prognosis of jaundice. The contents of this chapter can be induced by(from) yellowing and jaundice These two disease patterns assume various aspects of disease cause, pathomechanism, symptom, prognosis, and treatment. Jaundice was at first classified into liquor jaundice,dietary irregularly jaundice, black jaundicem abd sextual taxation jaundice, later classified into liquor jaundice, dietary irregularly jaundice, black jaundice, sextual tatation jaundice, and yellow sweat. the disease cause and pathomechanism of jaundice are said to be said to be due to the damp-heat, which is attacked with the evil of wind and dampness to affect the spleen-stomach and the liver. and to the inveterate drinking, damage by food, sextual taxation jaundice, sextual taxation, and vacuity taxation. This chapter mainly refers to jaundice as damp-heat, so that it lays down fundamental principles of clear heat and disinhibit dampness. In the prognosis of jaundice, ingibited urination shows symptoms of jaundice, and neither urination nor damp-heat develops symptoms of jaundice. and jaundice with thirst is difficult to cure, and that the symptoms of the abdominal fullness is also difficult to cure, while jaundice without thirst is ease to cure. Of the 18 days of suffering from jaundice, the symptoms of jaundice get better before and after 10 days. I think, however, that getting worse of its symptoms makes more meaningful clinically.
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    OBJECTIVE: The authors’ goal was to determine the concentration of antidepressants in amniotic fluid during maternal treatment of depression. METHOD: Women treated with antidepressants undergoing amniocentesis for obstetrical reasons were enrolled. Antidepressant concentrations in amniotic fluid and maternal serum were determined with high-performance liquid chromatography. RESULTS: Amniotic fluid was obtained from 27 women, and the amniotic fluid’s antidepressant concentrations were highly variable. For the parent compounds, the amniotic fluid concentrations of selective serotonin uptake inhibitors averaged 11.6% (SD=9.9%) of maternal serum concentrations (N=22). Amniotic fluid to maternal serum ratios were higher for venlafaxine: 172% (SD=91%) (N=3). Of interest, the amniotic fluid to maternal serum ratios for the metabolites (N=19) did not demonstrate a consistent pattern compared to the parent compound ratios. In 10 subjects, the amniotic fluid to maternal serum ratio for the metabolites was higher than the parent compound and lower in the remaining nine subjects. CONCLUSIONS: The pattern of antidepressant concentrations in amniotic fluid is similar to recent data for placental passage. Although the significance of amniotic fluid exposure remains to be determined, these results demonstrate that maternally administered antidepressants are accessible to the fetus in a manner not previously appreciated.
    Amniocentesis
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    Background TT virus (TTV) hepatitis is an infectious disease which can have both hepatic and extrahepatic manifestations, and it is transmitted prevalently parenterally, and rarely by enteral way. The prevalence of TTV in donors in the USA is 1%, from 1.9-10% in Great Britain, in Japan 12%, in Thailand 7-30%, in Russia 10-20%, and in Brazil 62%. In patients with cryptogenic cirrhosis, the TTV was revealed in 15% of the cases, and 27% in fulminant hepatitis, 40% in hemophiliacs, 47.9% in those with hemodialysis. Case report We present a clinical case with viral TTV hepatitis revealed in a young person born in 1987, from a village in the northern part of Moldova. He fell ill at the beginning of January 2012 being absolutely healthy when a rash appeared, an erythematic eruption on the cheeks and the nasal pyramid, moderate pains in the joints and abdominal discomfort. At the moment of falling ill he worked in Russia at the construction of the Olympic Complex in Soci. He consulted a doctor which suspected him of systemic lupus erythematosus, but it was not confirmed in the laboratory, and no treatment was administered. The symptomatology of the disease disappeared. But in May (5 months from the time the first symptoms appeared) the pains in the joints reappeared, mostly in the big joints. He addressed the Infectious Diseases Clinic of the State Medical and Pharmaceutical University “Nicolae Testemițanu” and during the objective examination, a moderate hepatomegaly was confirmed at an ultrasound examination: the right lobe
    Fulminant hepatitis
    Medical microbiology