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    The contribution of diastolic dysfunction in patients with preserved left ventricular (LV) systolic function to impaired functional status and cardiac mortality in myocardial infarction (MI) is unknown. In the present study, assessment of LV diastolic function was performed by Doppler analysis of the mitral and pulmonary venous flow, and the propagation velocity of early mitral flow by color M-mode Doppler echocardiography in 183 consecutive patients at day 5-7 following their first acute MI. Patients were classified into four groups: group A: preserved LV systolic and diastolic function (n = 73); group B: LV systolic dysfunction with preserved diastolic function (n = 10); group C: LV diastolic dysfunction with preserved systolic function (n = 60); group D: combined LV systolic and diastolic dysfunction (n = 40). The cardiac mortality rate at 1 year was significantly higher in groups C (13%) and D (38%) compared to A (2%) (p < 0.01). Multivariate regression analysis identified LV diastolic dysfunction (p = 0.001), Killip class >or=II (p = 0.006), and age (0.008) as predictors of cardiac death or readmission due to heart failure. The presence of LV diastolic dysfunction with preserved systolic dysfunction is associated with increased morbidity and mortality following acute MI.
    Killip class
    Systole
    Citations (29)
    This chapter contains sections titled: Introduction Definition and physiology of diastole Echocardiographic techniques for assessing diastolic function Diastolic disease Diastolic function in pediatric patients without heart disease Strategy for the echocardiographic assessment of diastolic function in children Conclusions References
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    Dr. Philip Liebson from Rush Medical College, Chicago, IL, moderated the topic “Evaluation of Diastolic Function: How Practical Is it?” with Drs. Rami Doukky and Melissa Tracy from Rush Medical College, Chicago, IL. The discussion focused primarily on: The interpretation and importance of echocardiogram reports on diastolic function; the difference between diastolic dysfunction and diastolic heart failure; the role of diastolic dysfunction and diastolic heart failure in the management of cardiac patients; and recent advances in the evaluation of diastolic function in echocardiography and other noninvasive measurement of diastolic function. (Med Roundtable Cardiovasc. Ed. 2014;3(4):218–225) ©2014 FoxP2 Media, LLC
    Diastolic heart failure
    Citations (0)
    This chapter contains sections titled: Introduction Phases Of Diastole Non-Invasive Assessment Of Left Ventricular Diastolic Function New Advances In The Echocardiographic Assessment Of Diastolic Function Estimation Of Left Ventricular Filling Pressures Pitfalls And Limitations In The Assessment Of Diastolic Doppler Analysis How To Interpret Left Ventricular Diastolic Filling Patterns In Clinical Practice
    Ventricular filling
    Ventricular Function
    Citations (0)