logo
    Properties of Bovine Thyroid Ribosomes and Polyribosomes
    Endocrinology (1968)
    Yusuke KondoP. De NayerL. W. LabawJohn B. RobbinsJ. E. RALL
    9
    Citation
    1
    Reference
    10
    Related Paper
    Abstract:
    Ribosomes and polyribosomes were prepared from bovine thyroid glands. Single ribosomes were similar to those from other mammalian tissues. The distribution of polyribosomes was also similar to that in other tissues. Despite attention to problems of mechanical, enzymatic and chemical breakage, bovine thyroid cells were found to have very few polyribosomes larger than 35 ribosomes, determined by electron microscopy. The heavy fractions consisted in the main of polyribosomes composed of 20 to 30 ribosomes, which are substantially smaller than predicted from the chain molecular weight of the thyroglobulin subunit (165,000) and the MW/ribosome ratio of 3–4000 estimated for other proteins. (Endocrinology83: 1117, 1968)
    Keywords:
    Polysome
    Thyroglobulin
    Topics:
    RNA modifications and cancer
    RNA and protein synthesis mechanisms
    Dissociation of Ribosomes on Polypeptide Chain Termination and Origin of Single Ribosomes
    Nature (1970)
    Raymond Kaempfer
    Polysome
    Eukaryotic Ribosome
    Polypeptide chain
    Citations (70)
    Purification, identification, and functional analysis of polysomes from the human pathogen Staphylococcus aureus
    Methods (2016)
    Régine BrielleMarie-Laure Pinel-MarieSophie ChatReynald GilletBrice Felden
    Polysome
    Translational regulation
    Ribosomal protein
    Citations (4)
    Significance of the free 70 s ribosomes in Escherichia coli extracts
    Journal of Molecular Biology (1968)
    Robert Ε. KohlerEliora Z. RonBernard D. Davis
    Polysome
    Puromycin
    Citations (117)
    Stability of free ribosomes, derived ribosomes and polysomes of the sea urchin
    Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis (1971)
    Anthony A. InfantePeter N. Graves
    Polysome
    Nuclease
    Citations (32)
    Rotational diffusion of Escherichia coli ribosomes
    Biochimie (1977)
    François PochonB. AmandDaniel Lavalette
    Polysome
    30S
    Rotational diffusion
    Citations (5)
    Ribosomes from HeLa cells
    Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects (1964)
    D. WinckelmansM. HillM. Errera
    Polysome
    HeLa
    Differential centrifugation
    Eukaryotic Ribosome
    Citations (14)
    Synthesis of high molecular weight thyroglobulin peptides by thyroid polysome in vitro
    Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis (1979)
    Yew Phew SeeGerard N. Burrow
    Polysome
    Thyroglobulin
    Molecular mass
    Sodium dodecyl sulfate
    Citations (4)
    Destruction by RNase of 30 s and 50 s ribosomes from Streptococcus pyogenes
    Journal of Molecular Biology (1964)
    Eugene L. HessRichard Horn
    Polysome
    Eukaryotic Ribosome
    Citations (10)
    Polyribosome metabolism in bacteriophage T4 infected Escherichia coli
    Archives of Biochemistry and Biophysics (1974)
    Marcia L. WalshPaul S. Cohen
    Polysome
    Deoxyribonucleases
    Citations (4)
    Properties of Bovine Thyroid Ribosomes and Polyribosomes
    Endocrinology (1968)
    Yusuke KondoP. De NayerL. W. LabawJohn B. RobbinsJ. E. RALL
    Ribosomes and polyribosomes were prepared from bovine thyroid glands. Single ribosomes were similar to those from other mammalian tissues. The distribution of polyribosomes was also similar to that in other tissues. Despite attention to problems of mechanical, enzymatic and chemical breakage, bovine thyroid cells were found to have very few polyribosomes larger than 35 ribosomes, determined by electron microscopy. The heavy fractions consisted in the main of polyribosomes composed of 20 to 30 ribosomes, which are substantially smaller than predicted from the chain molecular weight of the thyroglobulin subunit (165,000) and the MW/ribosome ratio of 3–4000 estimated for other proteins. (Endocrinology83: 1117, 1968)
    Polysome
    Thyroglobulin
    Citations (9)