Effect of Chorionic Gonadotropin on the Pouch of the Marsupial Trichosurus vulpecula
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Marsupials are viviparous, placental mammals that have evolved independently from the same ancestor as the eutherian mammals, which include humans and the principal laboratory animals. As a result of this evolutionary divergence, marsupial structure and function embody alternative solutions to many of the problems of mammalian existence. This dichotomy between marsupials and eutherian species suggests the use of marsupial models to provide innovative laboratory approaches that may facilitate experimental access to specific aspects of normal and abnormal human anatomy and physiology. Those characteristics that endow marsupials with their unique but largely unexploited biomedical research potential are identified and evaluated.
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The honey possum Tarsipes rostratus , a shrew‐sized marsupial endemic to south‐western Australia, feeds exclusively upon nectar and pollen. Tarsipes has fewer pouch‐young, which remain in the pouch longer, than the young of sympatric insect‐feeding marsupials of comparable size. Tarsipes pouch‐young were recorded in every month of the year. Of all adult females caught, 68% had pouch‐young and 36% of the remainder had recently carried young. This continual reproduction is offset by an average lifespan of only about one year. Although Tarsipes have four teats, only very few of the largest females reared four young to independence. The number of pouch‐young was inversely related to their size, changing, on average, from 3.6 young immediately after birth to 2.4 young at pouch‐exit. Larger females gave birth to larger litters than smaller females and appeared more successful in rearing them. Variation in the initial litter size, and any subsequent reduction in litter size, might allow females to optimize offspring production during their short lifetime in relation to an unpredictable and specialized food supply.
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