Effect of Enalapril on Left Ventricular Diameters and Exercise Capacity in Asymptomatic or Mildly Symptomatic Patients With Regurgitation Secondary to Mitral Valve Prolapse or Rheumatic Heart Disease
Roney Orismar SampaioMax GrinbergJoão J. LeiteFlávio TarasoutchiWilliam Azem ChalelaMarisa IzakiGuilherme Sobreira SpinaE RossiCharles Mady
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Mitral valve regurgitation
Mitral valve prolapse
Mitral valve prolapse
Abnormality
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The diagnosis of mitral valve prolapse (MVP) should depend on the presence of significant mitral regurgitation or mitral complex abnormality as far as MVP is a diseased status. Concerning the echocardiographic diagnosis, the site of prolapse is difficult to determine correctly. In this study, Doppler color flow mapping was used to detect mitral regurgitation, and to decide the site of prolapse. Our new criteria of MVP include: (1) Phonocardiographic or auscultatory findings suggestive of mitral regurgitation or mitral complex abnormality. (2) A systolic bulging or an apparent systolic ballooning of the mitral valve by two-dimensional echocardiography. (3) A mitral regurgitant signal with an acceleration flow at the site of prolapse by Doppler color flow mapping.
Mitral valve prolapse
Color doppler
Abnormality
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Mitral valve regurgitation
Mitral valve prolapse
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Objective To evaluate the localization of mitral valvular(MV)prolapse by transthoracic echocardiography(TTE),transesophageal echocardiography(TEE)and explore the interrelationship between the different subregions of MV prolapse and mitral regurgitation(MR).Methods Total of thirtythree patients with MV prolapse and more than moderate MR were included.TEE was used to further judge the location of scallop lesions and the result of both TTE and TEE were compared with the surgical findings respectively.The relationship between the different subregions of MV prolapse and MR was analyzed.Results Compared with the surgery findings,the accuracy rate of TTE and TEE in diagnosis of MV prolapse was 100％ qualitatively,80％ for TTE and 94％ for TEE in localizing the diseased region with the anterior and posterior MV,the result of TEE was significantly different from TTE(P＜0.05).MR level was related to the location of MV prolapse.Conclusions Compared with the TTE,TEE had more advantages in localizing the position of the MV prolapse.Mitral regurgitation is related to the location of MV prolapse.
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Echocardiography; Echocardiography,transesophageal; Mitral valve prolapse; Anatomical regions
Mitral valve prolapse
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Abstract: The Framingham Heart Study group has described the non-diagnostic variants may evolve into mitral valve prolapse over time. These non-diagnostic variants include minimal systolic displacement, and abnormal anterior coaptation which is measured on surface echocardiography. Computed tomography and cardiac magnetic resonance imaging are evolving and can assess the degree of mitral regurgitation (MR); imaging techniques aside, genetic and proteomic detection of mitral prolapse is also evolving. However, the genetic basis for mitral prolapse is complex and likely involves multiple genetic loci. The same is also true for work determining possible biomarkers associated with mitral prolapse. The present study may be useful in counseling patients with a family history of mitral prolapse. Registry data is therefore of paramount importance in providing unbiased insight into this common disease.
Mitral valve prolapse
Mitral annulus
Framingham Heart Study
Chordae tendineae
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Mitral valve prolapse
Parasternal line
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Abstract Abstract Ynaraja, E., Caro, A. and Montoya, J.A. 2002. Effect of treatment with enalapril, frusemide and a low-sodium diet on dogs with mitral regurgitation. J. Appl. Anim. Res., 22: 219–224. Thirty-five dogs with congestive heart failure due to chronic mitral valve disease were treated with frusemide (1 mg/kg bid), enalapril (0.4 mg/kg bid) and a low-sodium diet to evaluated the effects produced by combination of these drugs and to ascertain the possible negative effects following the use of these drugs. The treatment was safe, effective and well tolerated. No major side effects and no significant changes in haematological and biochemical variables were observed. Keywords: Dogmitral diseasefrusemideenalaprillow-sodium dietcardiologyCHF
Low sodium diet
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